Modern Healthspan

In this video Professor Sebastiano discusses how the timing of the therapy might work, concerns of whether the "point of no return" might be crossed and what aspects of aging are not covered by partial cellular reprogramming. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bi...

In this episode Professor Sebastiano discusses the three most advanced interventions that Turn Bio is working on, for skin, immunology and muscles and when they will be available for human trial. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to...

In this episode Professor Sebastiano discusses the results that he and his team have had in rejuvenating human cells and how the process could be applied as well as their experience rejuvenating a muscle in an old mouse. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is...

In this episode Professor Sebastiano discusses the results that he and his team have had in rejuvenating human cells and how the process could be applied as well as their experience rejuvenating a muscle in an old mouse. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is...

In this video Professor Sebastiano discusses how the mRNA is delivered to the specific cells and how the recent explosion of mRNA interest has changed the development landscape. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this tec...

In this episode Professor Sebastiano introduces ERA, Epigenetic Reprogramming of Age technology and talks about his thoughts on some of the causes of aging Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical...

In this episode Dr Newman talks about ketones as a fuel for the brain and how this becomes more important as we age and the brain can become less able to use glucose. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence o...

In this episode Dr Newman talks the ITP lifespan trials that used butanediol but did not see a significant result. He covers what might have caused this and some of the chemistry behind butanediol and butyrate. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therap...

In this episode Dr Newman talks ways of boosting ketones through ketone supplements, what the different types are and what has been seen with them in human trials. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of o...

In this episode Dr Newman talks about experiments that he and other teams have run on mice lifespan and healthspan while they were on ketogenic diets. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults....

In this episode Dr Newman discusses ketones and their impact on aging. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the molecular details of how diet regulate the...

In this episode Dr Davidsohn discusses the next generation therapies that Rejuvenate Bio are working on. We also discuss, klotho, RJB02 and his personal protocol. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebio.com/ Dr Davidsohn's paper mention...

In this episode Dr Davidsohn discusses taking RJB01 to trial with humans for a rare heart disease and how gene therapy is viewed by the FDA. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebio.com/ Dr Davidsohn's paper mentioned in the interview A...

In this episode Dr Davidsohn discusses how the gene therapy helps with heart health and is only required one time. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebio.com/ Dr Davidsohn's paper mentioned in the interview A single combination gene th...

In this episode Dr Davidsohn talks about the first therapy Rejuvenate Bio is working on which restores a more youthful protein expression in the liver which then impacts the rest of the body. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebio.com/...

In this episode we discuss some of Dr Davidsohn's background, the mission of Rejuvenate Bio and the gene therapy that was developed at Dr Church's lab and is now being used to treat companion dogs. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebi...

In this episode Dr Verburgh talks about his personal longevity protocol. Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases And is available here: https://pubmed.ncbi.nlm.nih.gov/25470422/ Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, me...

In this episode Dr Verburgh talks about his theory of aging and why he thinks that epigenetic dysregulation is the most fundamental of the hall marks. Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases And is available here: https://pubmed.ncbi.nlm.nih.gov/25470422/ Dr Kris Verburgh is a medical doctor and research...

In this episode Dr Verburgh talks about his thoughts on the escape velocity of aging and what it might mean for humanity. Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases And is available here: https://pubmed.ncbi.nlm.nih.gov/25470422/ Dr Kris Verburgh is a medical doctor and researcher at the Free University of...

In this episode Dr Verburgh talks about developments in using mobile phones as a diagnostic device. Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is the Longevity Code. Dr Verburgh is a co-founder of NOVOS labs and is a partner and head...

In this episode Dr Verburgh talks about some of the upcoming technologies which will impact the longevity space in the coming years, including improvements in gene editing and epigenetics. Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is...

In this episode Dr Verburgh talks about how to optimise our micronutrient intake. This is not simple as it is sometimes difficult to know whether you have sufficient of certain micronutrients just by looking at the blood. Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book...

In this episode Dr Verburgh talks what are the key elements of a longevity diet. Dr Verburgh first wrote a paper on this subject in 2015, which introduced the term Nutrigerontology. The paper is: Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases And is available here: https://pubmed.ncbi.nlm.nih.gov/25470422/ Dr K...

In this episode Dr Verburgh talks about his three (well, he cheats a bit and squeezes in 5!) supplements for aging. Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is the Longevity Code. Dr Verburgh is a co-founder of NOVOS labs and is a p...

In this episode Dr Verburgh talks about the founding of NOVOS and why NMN was their choice for the NAD booster Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is the Longevity Code. Dr Verburgh is a co-founder of NOVOS labs and is a partne...