Modern Healthspan

In this episode Dr. Longo talks about some of the practical aspects of the FMD, such as how often it should be followed and compares its benefits to those of exercise. Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology. Professor Longo has thirty years of...

In this episode Dr. Longo talks about the benefits of the FMD and who it is most appropriate for. Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology. Professor Longo has thirty years of experience in the field of longevity and healthy nutrition. His most...

In this episode Dr. Longo talks about his views on fasting and provides an introduction of what the FMD is and why it was first created. Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology. Professor Longo has thirty years of experience in the field of lon...

In this episode Dr Tanzi discusses whether Alzheimer's and other brain diseases are happening at a younger age and why that might be, along with his own protocol to maintaining a young and healthy mind! Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Diseas...

In this episode Dr Tanzi talks about some of the future potential options are to treat Alzheimer's once it has started and neural inflammation has set in. Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Ma...

In this episode Professor Tanzi talks about SHIELD, his acronym for the things that you can do to protect your brain. S - Sleep, H - Handle Stress, I - Interactions with friends, E - Exercise, L - Learn new things and D - Diet and we dive into detail on a few of them. Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-D...

In this episode Professor Tanzi talks about the causes of Alzheimer's, from the plaques and tangles to neural inflammation, and what treatments exist for these symptoms. Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (R...

Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Massachusetts General Hospital, and the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi co-discovered the first thr...

In this episode Professor Harries discusses the attitude of governments to aging, the most promising aging technologies and her personal protocol for staying healthy. Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she leads the RNA-mediated disease mechanisms group. Her group has interests in messenger RNA processing and epigenetic...

In this episode Professor Harries discusses her company Senisca, her theory of aging and getting funded for aging research Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she leads the RNA-mediated disease mechanisms group. Her group has interests in messenger RNA processing and epigenetic gene regulation in the context of ageing an...

In this episode Professor Harries discusses how oligonucleotides can be used for as a very precise way to control gene expression. Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she leads the RNA-mediated disease mechanisms group. Her group has interests in messenger RNA processing and epigenetic gene regulation in the context of a...

In this episode Professor Harries discuss how she and her team used resveralogs initially and later HS2 donors to change the regulation of splicing factors and in doing so, reverse cellular senescence. We also touch on what a therapy based on this might look like in the clinic. Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she lea...

In this episode Professor Harries discuss whether RNA Splicing meets the criteria of a hallmark of aging. To qualify it should i) manifest during normal aging ii) its aggravation should accelerate aging and iii) it amelioration should slow or reverse aging. Prof Harries goes through each of these criteria with respect to RNA splicing. Lorna Harries is Professor of Molecular Genetics at the Univers...

In this episode Professor Harries addresses some of the fundamental questions about RNA splicing and how it regulates gene expression Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she leads the RNA-mediated disease mechanisms group. Her group has interests in messenger RNA processing and epigenetic gene regulation in the context o...

In this video Professor Robbins discusses reprogramming using the Yamanaka Factors as the most promising technology in aging and its relationship to DNA damage. He also talks about his personal protocol for longevity. Dr. Robbins is a Professor of Biochemistry, Molecular Biology and Biophysics and Associate Director of the Institute on the Biology of Aging and Metabolism (iBAM) at the University o...

In this video Professor Robbins discusses the work his lab is doing with Exosomes or EV (Extra-Cellular Vesicles) and how these can impact senescent cells by suppressing SASP as senomorphics Dr. Robbins is a Professor of Biochemistry, Molecular Biology and Biophysics and Associate Director of the Institute on the Biology of Aging and Metabolism (iBAM) at the University of Minnesota. He was part of...

In this video Professor Robbins discusses the work his lab is doing, investigate what makes centenarians different at the genetic level and then to develop drugs which can mimic these differences. One of these differences is in SIRT6 and he talks about what they are doing to better understand this in collaboration with Prof Vera Gorbunova and colleagues at the Albert Einstein College of Medicine....

In this video Professor Robbins discusses the process by which his and other labs look for possible senolytics. He also talks about fisetin and why he chooses to take it Dr. Robbins is a Professor of Biochemistry, Molecular Biology and Biophysics and Associate Director of the Institute on the Biology of Aging and Metabolism (iBAM) at the University of Minnesota. He was part of a collaborative team...

In this video Professor Robbins discusses cellular senescence in general then dives into cellular senescence in the immune system. As immune cells are present through out the body, embedded in different tissues, their senescence has the ability to impact the system in ways that other senescent cells may not. Dr. Robbins is a Professor of Biochemistry, Molecular Biology and Biophysics and Associate...

In this video Professor Robbins discusses his theory of aging, the Unitary Theory of Fundamental Aging and how that helped his choice to work on aging rather than specific diseases. Dr. Robbins is a Professor of Biochemistry, Molecular Biology and Biophysics and Associate Director of the Institute on the Biology of Aging and Metabolism (iBAM) at the University of Minnesota. He was part of a collab...

In this video Dr Gundry talks about his theory of aging (which involves the gut and mitochondria of course!) and also his longevity protocol. Dr Steven Gundry is a world-renowned heart surgeon, medical researcher, and author. During his 40-year career, Dr Gundry has performed 10,000 heart operations and developed patented, life-saving medical technology. He has published multiple bestselling books...

In this video Dr Gundry discusses other ways of encouraging mitochondrial uncoupling, particularly in brown fat. He also covers thermogenic compounds, like ginger and tumeric and why they make you feel hot. Dr Steven Gundry is a world-renowned heart surgeon, medical researcher, and author. During his 40-year career, Dr Gundry has performed 10,000 heart operations and developed patented, life-savin...

In this video Dr Gundry discusses the top three supplements for healthy aging and also melatonin as a mitochondrial anti-oxidant Dr Steven Gundry is a world-renowned heart surgeon, medical researcher, and author. During his 40-year career, Dr Gundry has performed 10,000 heart operations and developed patented, life-saving medical technology. He has published multiple bestselling books focused on n...

In this video Dr Gundry discusses essential fatty acids, including ALA or alpha linoleic acid and C15. We also discuss the long term impact of the keto diet. Dr Steven Gundry is a world-renowned heart surgeon, medical researcher, and author. During his 40-year career, Dr Gundry has performed 10,000 heart operations and developed patented, life-saving medical technology. He has published multiple b...

In this video Dr Gundry discusses eating windows, which are best and how long we need to be fasting for the generation of ketones to start. We also discuss leaky gut! Dr Steven Gundry is a world-renowned heart surgeon, medical researcher, and author. During his 40-year career, Dr Gundry has performed 10,000 heart operations and developed patented, life-saving medical technology. He has published m...