Modern Healthspan

Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph. D. (summa cum laude) from University of Buenos Aires, Argentina, for his work o...

In this episode Dr Furman discusses chronic inflammation and how it differs from acute inflammation. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Fu...

In this episode Dr Kaufmann talks about her personal protocol, how many supplements she takes (52) and some of the more advanced therapies that she uses, such as exosomes. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of...

In this episode Dr Kaufmann talks about supplements and eye drops for aging eyes, including carnosine eye drops which may be able to reverse long sight. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufma...

In this episode Dr Kaufmann talks about supplements, that can be used to address loss of hair and loss of hair colour, including Ecklonia Cava a supplement from Japanese seaweed. We also cover sarcopenia where the supplements are leucine, collagen, resveratrol or pterostilbene and a source of nicotinamide, such as NMN or NR. Sandra Kaufmann, is a cell biologist who for the last seven years has bee...

In this episode Dr Kaufmann talks about the her list of required supplements for those who are over 40. This has the 5 from her original book, Pterostilbene, Astaxanthin, Nicotinamide, Carnosine, Curcumin. To which she has now added Quercetin, Lactoferrin and Spermidine. We also discuss some of them in more detail, touching on rapamycin and delivery systems such as liposomes and nano micelles. San...

In this episode Dr Kaufmann talks about her system for rating molecules for their efficacy based on the scientific evidence available. She also discusses her new book which extends from her first book and adds more supplements to the list. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is als...

In this video Dr Kaufmann provides an introduction of what led her to start studying aging and the process that she used to develop her 7 tenets. She then goes through the tenets explaining what each one is. She uses the analogy of a factory to show how the pieces fit together. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe D...

In this episode Dr Longo talks the diet and exercise for longevity and whether it is necessary to exercise when fasting. He also shares his own longevity protocol Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology. Professor Longo has thirty years of expe...

In this episode Dr Longo talks about the best timing for intermittent fasting, which he says is 12/12 and why 16/8 is not optimal. We also talk about eating patterns during the feeding window. Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology. Professor...

In this episode Dr Longo talks about how the fast mimicking diet can be used either in combination with other interventions or on its own to treat the major diseases of aging. He also covers progress towards getting the FMD approved as a drug by the FDA. Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Souther...

In this episode Dr. Longo talks about some of the practical aspects of the FMD, such as how often it should be followed and compares its benefits to those of exercise. Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology. Professor Longo has thirty years of...

In this episode Dr. Longo talks about the benefits of the FMD and who it is most appropriate for. Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology. Professor Longo has thirty years of experience in the field of longevity and healthy nutrition. His most...

In this episode Dr. Longo talks about his views on fasting and provides an introduction of what the FMD is and why it was first created. Valter Longo, PhD, is a professor of gerontology and biological sciences and the director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology. Professor Longo has thirty years of experience in the field of lon...

In this episode Dr Tanzi discusses whether Alzheimer's and other brain diseases are happening at a younger age and why that might be, along with his own protocol to maintaining a young and healthy mind! Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Diseas...

In this episode Dr Tanzi talks about some of the future potential options are to treat Alzheimer's once it has started and neural inflammation has set in. Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Ma...

In this episode Professor Tanzi talks about SHIELD, his acronym for the things that you can do to protect your brain. S - Sleep, H - Handle Stress, I - Interactions with friends, E - Exercise, L - Learn new things and D - Diet and we dive into detail on a few of them. Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-D...

In this episode Professor Tanzi talks about the causes of Alzheimer's, from the plaques and tangles to neural inflammation, and what treatments exist for these symptoms. Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (R...

Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Massachusetts General Hospital, and the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi co-discovered the first thr...

In this episode Professor Harries discusses the attitude of governments to aging, the most promising aging technologies and her personal protocol for staying healthy. Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she leads the RNA-mediated disease mechanisms group. Her group has interests in messenger RNA processing and epigenetic...

In this episode Professor Harries discusses her company Senisca, her theory of aging and getting funded for aging research Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she leads the RNA-mediated disease mechanisms group. Her group has interests in messenger RNA processing and epigenetic gene regulation in the context of ageing an...

In this episode Professor Harries discusses how oligonucleotides can be used for as a very precise way to control gene expression. Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she leads the RNA-mediated disease mechanisms group. Her group has interests in messenger RNA processing and epigenetic gene regulation in the context of a...

In this episode Professor Harries discuss how she and her team used resveralogs initially and later HS2 donors to change the regulation of splicing factors and in doing so, reverse cellular senescence. We also touch on what a therapy based on this might look like in the clinic. Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she lea...

In this episode Professor Harries discuss whether RNA Splicing meets the criteria of a hallmark of aging. To qualify it should i) manifest during normal aging ii) its aggravation should accelerate aging and iii) it amelioration should slow or reverse aging. Prof Harries goes through each of these criteria with respect to RNA splicing. Lorna Harries is Professor of Molecular Genetics at the Univers...

In this episode Professor Harries addresses some of the fundamental questions about RNA splicing and how it regulates gene expression Lorna Harries is Professor of Molecular Genetics at the University of Exeter College of Medicine and Health where she leads the RNA-mediated disease mechanisms group. Her group has interests in messenger RNA processing and epigenetic gene regulation in the context o...