TT HealthWatch

Program notes: 0:40 Human Phenotype project 1:43 Metabolomics 2:42 25 year follow up 3:43 Two control groups 4:00 CBT via telehealth or online 5:00 2000 people with chronic pain 6:00 Completion rate for videos lower 6:50 RNA analysis in cancer molecular diagnostics 7:50 4.8% failure rate 8:50 CNS or blood cancers primarily 9:25 Middle age exposure to air pollution and later cognition 10:25 Poorer...

Program notes: 0:44 Reanimating hearts for transplant 1:44 Allow heart to sit for two to four minutes 2:34 Outcomes in DCIS without surgery 3:34 Free of breast cancer six months after diagnosis 4:34 Numbers who went on to develop invasive disease low 5:34 May change how we approach DCIS 6:09 Suicidality around the world in older adults 7:09 Guns, pesticides, hanging 8:10 Increase primary care diag...

Program notes: 0:40 AHA risk calculator in various ethnicities 1:40 Works well in all of them 2:40 Women and ethnicities 3:00 Hepatitis C screening in EDs 4:01 Many ethnicities represented 5:01 Identified as having the virus 6:01 Once they tested only 24% were referred 7:01 It was free testing 7:40 Failing US children 8:41 78% more likely to die in the US 9:41 Some of these are preventable 10:24 L...

Program notes: 0:40 A novel way to help aphasia after a stroke 1:40 C7 nerve ligation 2:42 Somatosensory function versus speech processing 3:36 Substandard anticancer medications 4:40 Tested many using HPLC 5:40 Alarming that one in six is impacted 6:40 Paying out of pocket 7:38 New type of medicine for treatment resistant hypertension 8:38 Need to follow electrolytes 9:00 ED boarding for elderly...

Program notes: 0:40 Stem cells for type 1 diabetes 1:40 None had hypoglycemia afterwards 2:40 Autologous stem cells? 3:20 Oral GLP-1 agonist 4:20 Primary endpoint HbA1c reduction 5:20 Weight loss modest 6:20 Injectable GLP-1 plus an amylin analogue 7:20 Both those with diabetes and those without 8:20 No increased safety events 8:40 Mental health hospitalizations in adolescents 9:40 KID database 10...

Program notes: 0:35 Screen time trajectories in adolescents 1:33 31% had increasing addictive use trajectories 2:31 Females more involved in social media 3:06 Cannabis and CV risk 4:06 Smoking or using other products 5:06 Mechanisms include oxidative stress 6:06 Haven't regulated 6:28 Tau PET imaging in Alzheimer's 7:28 90% of tau positivity concurs with AB 8:30 Will blood test obviate? 9:30 Imagi...

This week's topics include family affluence and telomeres in children, gut bugs and respiratory illness in children, heat illness and homelessness, and low potassium diets and hypertension and diabetes. Program notes: 1:05 Heat illness and homelessness 2:05 No access to water 3:05 More likely in southern states 3:20 Telomere length, family affluence and cortisol 4:20 High affluence had longer telo...

This week's topics include treating hot flashes in breast cancer survivors, a blood test for detecting colorectal cancer, exercise to improve survival after colorectal cancer treatment and CAR-T therapy for solid tumors. Program notes: 0:40 CAR-Ts for solid tumors 1:40 Advanced gastric or gastroesophageal cancer 2:40 Cytokine release syndrome 3:22 Exercise after treatment for colorectal cance...

This week's topics include the worldwide burden of skin cancers, risk of a second stroke when a person is taking anticoagulants, patients supporting each other for weight loss maintenance, and imaging for dense breasts. Program notes: 0:45 Dense breast tissue imaging 1:40 MRI and contrast enhanced mammography superior 2:40 Giving IV contrast with mammography 2:53 Burden of skin cancer in olde...

This week's topics include treating resistant hypertension, gabapentanoids and the risk of self harm, risk for depression after diagnosis of a medical condition, and fatty liver and pregnancy. Program notes: 0:35 Depression after medical condition diagnosis 1:36 Any of a number of medical conditions 2:37 A much lower risk in comparison group 3:37 Major depressive disorder could be number one cause...

This week's topics include USPSTF on screening for syphilis in pregnancy, when to take blood pressure medicines, comparing weight loss drugs, and a narrative intervention for PTSD after an ICU stay. Program notes: 0:40 NEJM publication of comparison of obesity medications 1:40 Tirzepatide versus semaglutide for 72 weeks 2:41 Also had reduction in blood pressure 3:26 Rise in congenital syphilis and...

Program notes: 0:40 Covid and flu vaccine 1:40 More immunogenic response 2:40 Female urinary incontinence treatment 3:40 Mid urethral sling or botox 4:40 Doesn't require surgery 5:40 Combined therapy group 6:10 Large language models and discharge summaries 7:10 100 hospital encounters  8:10 Maybe provides a draft 9:00 AI and diagnosing diabetic kidney disease 10:01 Large number of retinal ima...

Program notes: 0:47 Gun injuries and deer hunting season 1:47 Other associated injuries 2:47 Coincidence of hunting? 3:48 Restrict hunting guns to that use 4:10 Can we avoid surgery in some with cancer? 5:10 Dostarlimab treatment 6:10 Can help avoid surgery in few who have this mutation 7:10 Look at specific pathways 7:30 Lung cancer treatment 8:32 71% responded 9:12 Impact of Pepfar funding...

Program notes: 0:40 Polygenic risk score for prostate cancer 1:40 90th percentile or higher 2:40 Genetic risk for cancer 3:41 Avoid false positives 4:00 Cervical artery dissection and subsequent stroke risk 5:00 High in older people, Black and Hispanic people 6:00 Nonspecific symptoms may predict 7:00 Preventing clotting in patients with cancer 8:00 Standard dose followed by half dose 8:44 USPSTF...

Program notes: 0:33 TAVR outcomes improved 1:33 Dapagliflozin  2:33 Looked at comorbidities 3:00 Tolebrutinib for relapsing MS 4:00 Annualized relapse rate 5:00 Works in the CNS 6:00 First endpoint wasn't proven 6:20 Invasive group A strep 7:20 Become more resistant to antibiotics 8:01 Not a single type of group A strep 8:25 Hearing loss and heart failure 9:25 Psychological distress...

This week's topics include aging and diet, blood based biomarkers for dementia, ten and thirty year risk for cardiovascular disease, and global effect of cardiovascular risk factors. Program notes: 1:00 Five factors and cardiovascular disease 2:00 Additional life years free of CVD 3:00 Irrespective of where you live 3:27 Optimal dietary patterns for healthy aging 4:28 Higher intake of fruits,...

This week's topics include a better way to treat A-fib, managing bleeding in cardiac surgery, penicillin for strep infections, and treating pulmonary hypertension. Program notes: 0:55 Ablation for afib 1:51 Pulsed field ablation PFA 2:55 Training physicians 3:23 Prothrombin complex versus frozen plasma 4:24 Noninferiority outcome 5:24 Documented bleeding issue 6:25 New treatment for pulmonary hype...

This week's topics include cell signatures in PCOS, a new technique for prostate biopsies, improving the safety of carotid endarterectomy, and long term risk after TIA. 0:41 Long term risk of stroke after TIA 1:39 About one in five over the next ten years 2:40 Need to continue antiplatelet agents 3:33 New technique for prostate biopsy 4:36 Biopsy naive men 5:35 Microultrasonography used 6:35...