TT HealthWatch

Program notes: 0:40 Online prescribing of GLP1s 1:44 Physician asks a number of questions 2:44 Interaction to approval about five minutes 3:30 Respiratory outbreak mitigation in nursing homes 4:30 Using PCR-based test in the nursing home 5:30 No difference in outbreak number or size 6:35 Avoid 64,000 ED transfers in U.S. 7:32 Residents reap many benefits 8:00 Inhalation treatment for pulmonary fib...

This week's topics include technology to improve stroke outcomes, adult use of social media and health decisions, impact of social media ban on Australian youth, and an LLM to augment clinical management in a low resource setting.

Program notes: 0:40 Electronic patient messaging 1:40 Not baked into the usual workday 2:40 Managing patient expectations 3:33 Tranexamic acid in noncardiac surgery 4:33 Almost 9,000 patients enrolled 5:30 Does it increase VTE? 6:31 UK attempted 10 years ago 7:00 CAR-T cell outcomes 10 years later 8:01 Somewhere between 10-15% would have relapsed 9:03 Patellar resurfacing in total knee replacement...

This week's topics include SES and brain development in kids, lifestyle changes and multimobidity, food labeling and childhood obesity, and prehabilitation in elders.

This week's topics include visceral fat and CVD risk factors, delirium and cognitive decline and hospitalization, caps on insulin price, and factors involved with IBD.

Program notes: 0:35 Cell-free DNA screening for cancer and diagnosis delays 1:35 Populations-based screening 2:35 24 different companies offer liquid biopsy 3:01 Can we prevent chronic back pain after acute back pain? 4:01 Impact score on chronic back pain 5:01 Real-world setting lacks impact 6:01 Primary care role 7:01 Individual should assess their own back pain 7:25 Resistance training and mort...

This week's topics include duration of dual anticoagulation following bypass grafting or stents, how has management of miscarriage changed, at home rehab after an ICU stay, and weight loss for atrial fibrillation.

Program notes: 0:37 Prehospital resuscitation with whole blood 1:37 Compared with blood components 2:35 Easier to store  3:19 Azithromycin in wheezing kids 4:19 Treated for five days 5:26 Name change from PCOS to PMOS 6:26 Consensus build 7:28 Improved accuracy of pathophysiology 8:30 Adjust policy, change international classification 9:15 Biomarkers to direct lung cancer screening 10:15 Part...

Program notes: 0:36 24 hour ambulatory blood pressure and exercise 1:36 Aerobic, combined and HIT helped 2:36 Some combined with other things known to be beneficial 2:54 Medium sized vessel thrombectomy 3:54 Thrombectomy or medical management 4:54 Carefully selected patients benefit 5:55 About fifty to sixty percent end up with minimal impact 6:40 Digoxin as fifth pillar of congestive heart failur...

Program notes: 0:40 Transcranial stimulation for ASD 1:40 Used evoked potential and quick pulses 2:41 Motor cortex associated with speech and language 3:27 A model for benefits from GLP-1 use 4:27 Discern who would be most likely to develop obesity complications 5:27 Target to those more likely to have comorbidity 6:10 GLP-1 and AUD 7:10 Followed for 26 weeks 8:10 Side effects when someone doesn't...

Program notes: 0:35 Factors regarding vaccine uptake 1:35 Adolescents didn't like human to human 2:35 Free vaccines helpful 3:00 Treating osteoarthritis of the knee 4:00 Dose response to reduce pain score 5:00 Does it elicit an immune response 5:35 Factors in increasing cancer rates in younger people 6:35 Things other than patient attributable factors 7:35 Unregulated growth with exposure 8:00 Tre...

Program notes: 0:30 Controlling HTN after intracerebral hemorrhage 1:30 Triple pill or placebo 2:30 Only effective treatment is lowering blood pressure 3:32 Serum creatinine levels 4:15 Is there a role for Paxlovid? 5:15 Did not reduce hospitalization or death 6:10 Fast antimicrobial susceptibility test for gram negative 7:10 Desirability of outcome ranking or DOOR 8:10 Median time to effective th...

Program notes: 0:34 Chronotrope type and timing of exercise 1:36 Sedentary adults and morning or evening type 2:36 Acting as your own control 3:10 Stenting for post thrombotic syndrome 4:10 Severity lower with endovascular therapy 5:10 Patent in 2/3 at six months 6:10 Very diverse patient populations 6:28 Estimating kidney function 7:28 Currently underestimate compromise 8:27 Deprescribing proton...

Program notes: 0:36 How low should cholesterol be targeted in secondary prevention? 1:40 33% reduction with target to 55 2:36 Able to do it with statin and other drugs 3:03 Deprescribing levothyroxine 4:06 Were able to discontinue in many 5:05 Thyroid not as responsive with aging 6:05 Barriers to deprescribing? 6:31 Treatment of HTN in low-income patients 7:31 75% unemployed 8:31 Patient participa...

Program notes: 0:38 Migrating biopharma industry 1:36 Early stage development 2:36 Need to replicate studies 3:23 Treatment for fatigue from long Covid 4:25 Fluvoxamine or metformin 5:25 Only fluvoxamine helped 6:25 Only for fatigue 6:35 How treatments for hepatitis C have been used 7:36 Number of people receiving treatment declining 8:36 Need a better system 9:16 Dulaglutide or tirzepatide and pa...

Program notes: 0:36 High versus standard-dose flu vaccines in older people 1:36 Cardiovascular outcomes 2:26 Also in those with previous CVD 3:10 Cooking and dementia risk 4:10 Cooking frequency and skills assessment 5:10 Tasks relative to preparing a meal at home 6:10 Encourage home cooking 6:30 Asymptomatic aortic stenosis treatment 7:30 Replace valve before symptoms 8:30 Trained cardiologist ca...

Program notes: 0:35 New cholesterol lowering guidelines 1:35 Risk scores new 2:35 Mainstay is behavioral change 3:35 For those with a longer view 4:00 AI based glaucoma screening in primary care settings 5:00 Either AI or pressure 6:00 Fundus photograph and intraocular pressure 7:00 Sensitivity and specificity 7:50 Diet and brain structure 8:50 Brain imaging over ten or fifteen years 9:50 Diet tha...

Program notes: 0:44 Adolescents and sleep duration 1:44 Very short sleep duration 2:44 Increased among all subgroups 3:45 Structural factors more important 4:45 Moving school start later 5:02 GLP1 agonists and various patient characteristics 6:02 Greater weight loss in women 7:06 A blood test to predict onset of symptomatic Alzheimer's 8:06 Median error of 3-4 years 9:06 Window of 11.4 years for a...

Program notes: 0:37 HIV treatment monthly injections 1:37 Long acting and effective 2:37 Some didn't come for monthly injections 3:16 COVID-19 vaccination and preeclampsia rate 4:16 In two successive cohorts during pandemic 5:16 Pre-existing morbidity 58% reduction 6:15 COVID-19 cytokine storm? 6:45 Monkeypox treatment 7:45 Randomized to placebo or smallpox drug 8:50 Menstrual blood to test for HP...

Program notes: 0:37 Hormone therapy and mortality 1:37 Those who used versus those unexposed 2:35 Different types of HT 3:32 Adolescent cannabis use and mental illness 4:32 Screened in physician office 5:32 Action at societal and government levels 6:00 Access to dialysis facilities and SES 7:01 2.3 % of advantaged communities lacked access 8:01 For profit centers consolidate 9:01 Roughly half of n...

Program notes: 0:35 Diabetes and food prescriptions 1:35 Got a food card to purchase nutritious foods 2:32 More than half didn't use it or used it less than 60% 3:00 Adequacy of a planetary health diet 4:00 Micronutrient intake and biomarkers 5:00 Doesn't seem to compromise long-term health 6:12 Statin recommendations and patient preferences 7:00 Benefit/risk analysis for patients 8:00 Patient's d...

Program notes: 0:38 Removal of fallopian tubes to prevent ovarian ca 1:43 129 studies included 2:43 Women who no longer desire pregnancy 3:40 Technically feasible 4:30 New oral PCSK9 inhibitor 5:35 Think it's a slam dunk 6:08 EHR helping deprescribing in older adults 7:08 Two sequential EHR interventions 8:08 40% more likely in one group 9:08 Something in email less effective 9:50 Benefits of knee...

Program notes: 0:50 Rapid recovery of hearts for transplant after circulatory death 1:50 Total ischemic time longer than 4 hours 2:50 Typically reanimate 3:50 Expanded to donors 40 years of age 4:55 Do women with PCOS have increased risk for arrhythmia 5:55 Incidence arrhythmia in these women increased risk 6:50 An LLM to streamline transitions from primary to secondary care 7:50 Used alone, with...

Program notes: 0:45 Impact on kids of parental firearm injury or death 1:46 Eight additional psychiatric diagnoses per 100,000 2:39 Lifetime stress, inflammation and racial disparities in mortality 3:40 Black individuals shorter survival 4:40 Precise number is difficult to understand 5:40 Self-report 6:45 If a woman has known CVD, can she discontinue statins in pregnancy? 7:45 No difference in wom...

Program notes: 0:40 Two MMWR reports on wastewater to detect measles 1:40 Subsequent detection after early identification 2:40 Watch worldwide transition 3:15 Weight regain after medication for weight management 4:16 Cardiometabolic risk factors return in just over a year 5:16 Willingness to use declined with knowledge of regain risk 6:16 Prevention of obesity 6:33 Chronic kidney disease and heart...