TT HealthWatch

Program notes: 0:38 Childhood vaccinations nationally 1:30 Across 45 states and DC 2:34 Level of vaccine protection 3:34 Professional societies stepping in 3:51 Skilled nursing facilities  4:51 Estimated operating capacity 5:51 Backups into hospitals 6:51 Staffing not returned to pre-pandemic levels 7:35 Prescribing patterns of CNS active meds in older adults 8:36 Several classes of medi...

Program notes: 0:35 Global pain burden 1:35 Prevalence increased in 15 countries 2:35 Higher prevalence in older people but not consequence of aging 3:02 Tertiary patents 4:03 in the Orange Book 5:05 Prolonged patent protection and higher prices 6:07 Focused on high revenue products 6:50 Detecting DVT better 7:51 Age specific D-dimer cutoffs 8:51 Age and morbidity factors 9:23 Infant screen t...

Program notes: 0:40 IVF clinics and private equity 1:40 Provide over 54% of all IVF cycles in U.S. 2:41 Perhaps a more positive result 3:30 EKGs and liver cirrhosis 4:30 New diagnosis of advanced liver disease 5:30 Most physicians didn't follow up 6:18 Management of acute back pain 7:18 Did it improve pain or disability? 8:18 Four- to eight-hour-long sessions to teach 8:46 Lay health worker led in...

Program notes: 0:40 Saturated fat and CVD 1:40 When it was reduced in diet only helped in those with high risk 2:40 Obesity, diabetes and metabolic syndrome also important 3:30 Diagnostic follow up after lung CT 4:30 Less intensive than recommended in non-Hispanic blacks 5:31 Herpes antiviral and Alzheimer's 6:30 Followed for five years 7:30 80-90% of population exposed 8:30 Change screening crite...

Program notes: 0:37 Breast density knowledge outcomes 1:37 Breast density notification and education 2:37 Can't assess the import individually 3:30 CV outcomes with tirzepatide 4:30 HbA1c 8.4 5:30 GLP-1s have many benefits 6:30 No difference in adverse events 7:10 Covid vaccination in pregnancy 8:10 20K women included 9:10 Initial benefit is it durable? 9:30 Complex regional pain syndrome treatmen...

Program notes: 0:35 Should surgery efficacy 1:30 10-year follow of ASD surgery 2:30 Exercise does relieve pain 3:00 Association of pain with intrinsic capacity and inflammation 4:00 Domains including locomotion and others 5:01 Pain impacts a number of capacities 6:01 Aspirational to figure out pain 6:30 Scheduling birth at term to avoid preeclampsia 7:30 High-risk pregnancy delivered at term 8:35...

Program notes: 0:35 Update on RSV, flu and COVID-19 vaccines 1:35 500 studies included 2:35 Rare myocarditis 3:35 Flu vaccine in older adults 4:30 Tai chi or CBT-I for chronic insomnia 5:30 Trained in one or the other 6:30 Inexpensive and accessible 7:30 $150 billion cost of chronic insomnia 7:45 GLP-1s and WHO guidance 8:50 Multimodal approach required 9:45 Prevention is important 9:55 Corticoste...

Program notes: 0:40 CVD risk factors and texting 1:40 How many undergo screening? 2:41 Impact of personalized messaging 3:25 Decentralized trials versus centralized  4:25 Decentralized much larger 5:25 Does the trial move in one way or another? 6:15 Two studies related to use of peripregnancy GLP-1 use 7:15 Stopping at pregnancy 8:15 Is overweight worse than stopping? 9:00 Machine learni...

Program notes: 1:25 mRNA flu vaccine 2:25 Phase three trial 3:25 Preventing infection with a respiratory virus 4:25 Prophylaxis with NSAID? 4:45 Umbrella review of acetaminophen in pregnancy, ASD and ADHD 5:42 Confidence was low to critically low 6:45 Other factors such as environmental exposures 7:22 Increasing potassium to prevent heart arrythmias 8:33 Increase with supplements or dietary a...

Program notes: 0:50 Fish oil supplements and hemodialysis 1:50 1200 individuals to fish oil or not 2:50 Needs another study 3:11 PCSK9 inhibitor in people without MI or stroke 4:13 3- or 4-point MACE 5:11 Getting LDL down helps 6:11 Addition of more than one oral agent 6:50 Right therapy for afib and a stent 7:50 Noninferiority trial 8:50 After 12 months single agent works 9:27 Anticoagulation aft...

Program notes: 0:37 An oral med for obesity 1:37 Five to 10% stopped medication 2:35 Need head-to-head trials with injectable 3:00 Stem cell infusion after MI and heart failure 4:01 Reduced heart failure in recipients 5:01 Twice as many in the control arm 6:01 Moving past BMI in predicting atherosclerosis 7:01 Especially in overweight but not obese 8:01 Almost 3000 participants in Brazil 8:25 Bloo...

Program notes: 0:45 Steps, more and longer? 1:45 8,000 steps or less 2:45 Nothing on intensity 3:30 Mediterranean diet for IBS 4:30 Reduction in IBS symptom severity scale 5:30 Easy to accommodate with high compliance 6:30 Exercise for knee osteoarthritis 7:30 All types of exercise examined 8:30 Initiated exercise to try to address 9:00 AI intervention in prediabetes 10:00 Based on diabetes p...

Program notes: 0:40 Nicotine reduction for various subgroups 1:40 Native American and Alaskan populations benefit most 2:42 Black, rural populations 10 million lives saved 3:40 19-39 million life years saved 4:00 Food insecurity and blood pressure 5:00 Food vouchers most successful 6:00 May be more involved and motivated 6:35 PFAS and infant brain architecture 7:35 Children assessed with MRI 8:30...

Program notes: 0:40 New drug for SLE 1:41 Monitored for a year 2:43 Only one pathway limited 3:00 AI and health care 4:00 How to assure compliance? 5:00 Policy changes needed 6:01 Pessimistic about oversight 6:50 Genetic treatment for ADA deficiency 7:50 Using a viral vector 8:50 A curative treatment 9:30 Social media and cognitive performance in adolescents 10:30 Low and high increasing social me...

Program notes: 0:40 Aldosterone as a risk factor for heart disease 1:40 Spectrum of renin-aldosterone levels 2:40 As many as 25-30% may have 3:11 All pharmacologic interventions for obesity tx 4:14 All effective compared with placebo 5:12 Meta-analysis  6:13 Very little data in overweight or massively obese 6:35 Where do U.S. antibiotics come from? 7:35 India leading country for finished prod...

Program notes: 1:21 Bronchiectasis treatment 2:22 Twenty sites in UK 3:20 Medical imaging and cancer risk in kids 4:20 3000 hematologic cancers 5:20 Consider other types of imaging 6:23 Head CT increases risk by 35% 7:24 Treating pulmonary arterial hypertension 8:24 Improved mortality in another trial 9:25 Antibody prevention of RSV in healthy infants 10:25 Healthy preterm and full term infan...

Program notes: 0:40 Private equity takeover of hospitals 1:40 Reduced salaries or staffing 2:40 Patients likely to cost system 3:30 Use of anti thymocyte globulin to slow down T1D in youth 4:30 Diagnosed within 9 weeks prior 5:30 Serum sickness in 82% of highest dose group 6:30 Incidence increasing by 2% per year over 20 years 7:00 Aspirin in CRC 8:00 1100 patients with mutation 9:00 Can this muta...

Program notes: 0:45 Intimate partner violence and CVD 1:45 12% reported stalking 2:46 Screening in primary care 3:47 Fifty to 200% increased risk 4:00 Number of psychiatric disorders and dementia risk 5:00 Important to be aware when mental health disorders exist 6:03 Anxiety and depression associated 6:33 Lipoprotein(a) and widespread vascular disease 7:31 High risk of extracoronary vascular disea...

Program notes: 0:45 LSD and treatment of generalized anxiety disorders 1:45 Change in anxiety score to 12 weeks post administration 2:45 100 micrograms appear most efficacious 3:45 Require inpatient 12 hours 4:44 Cardiac rehab in older patients after MI 5:44 Frail individuals can improve outcome 6:45 Oftentimes think it won't make a difference 7:10 CT and pregnancy outcomes 8:10 Linear relationshi...

Program notes: 0:53 Who needs a beta blocker after MI 1:53 Those with mild reduction of ejection fraction 2:53 Confined to those with 40-50% ejection fraction 3:15 Revascularization in NSTEMI 4:20 Composite outcome 5:20 Closes gap, do FFR 6:20 May not be physiologically significant 6:40 Is lifelong anticoagulation needed after ablation 7:41 Occurred less in those who stopped 8:30 RSV, cardiac even...

Program notes: 0:44 Drug prices around the world 1:41 German prices as standard 2:40 Wide variation in price and affordability 3:40 Generic pricing  4:20 ADHD meds and behavior choices 5:20 Largely treated with methylphenidate 6:20 Significantly impacted suicidality and other behaviors 6:49 AI assistance and colonoscopy skills 7:49 When you stop AI assistance 8:50 Does this apply to...

Program Notes: 0:44 Spuds are what we call potatoes 1:47 Followed for over 5million person years 2:45 No mechanism for why french fries are problematic 3:25 DASH4D diet for glycemic control 4:25 4 diets compared  5:25 Extends benefits outside hypertension 6:20 A new antibiotic for staph infections 7:20 IV therapy until cultures are negative 8:20 Cost of new therapy, cost effectiveness 8:...

Program notes: 0:40 Alteplase after stroke 1:40 Expand time window 2:40 Imaging crucial in use 3:20 Use of health care and mortality in those with dementia 4:20 Women used much less healthcare 5:20 Focus on prevention in women 5:50 IVF outcomes and weight loss 6:50 Did not appear to increase success with IVF 7:45 Ultraprocessed foods versus minimally processed foods 8:45 Randomized to one diet or...

Program notes: 0:40 Screening young adults for CRC 1:40 Four different screening options 2:41 Awareness issue 3:40 "Yuck" factor associated 4:34 Persistent Covid infections and variants 5:35 Who ends up with variants? 6:35 Did not render more infectious 7:35 Humans as mixing vessels 7:50 How do men and women respond to antithrombotics 8:50 15% reduction in MI 9:58 Long term contraceptives free and...

Program notes: 0:44 Flu consequences for young children 1:44 Fulminant course 2:44 16 kids of total unvaccinated 3:10 HPV, T-cell receptor signaling and SCC 4:10 Unresectable disease 5:10 Thought virus facilitated 6:10 Target in recurrent or metastatic disease 6:26 Nonpharmacologic intervention in older adults to improve cognition 7:26 More intensive program a little better 8:26 Eat better, e...