Mark Ebell

Primary Care Update

Health EN ↓ 219 episodes

Four healthily skeptical primary care physicians discuss the latest in primary care medicine. Join Essential Evidence Editor Mark Ebell MD, Rush University's Kate Rowland MD, MSU Professor of Medicine Gary Ferenchick MD, and POEMs co-founder Henry Barry MD, MS for this fast-paced weekly update on evidence-based primary care.

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Author

Mark Ebell

Category

Health

Podcast website

podcasters.spotify.com

Latest episode

Oct 30, 2026

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Episodes

Episode 219: antihistamines for eczema, POC tests for COPD, interval for polyp f/u, and retatrutide for weight loss 30.10.2026

Primary care faculty Gary Ferenchick, Kate Rowland, Henry Barry and Mark Ebell talk about 4 new studies: antihistamines for atopic dermatitis, point of care testing and antibiotics for COPD exacerbations, how long after polyp to do colonoscopy, and retatrutide triple agonist for weight loss 

Episode 218: multicancer early detection RCT, vit D for cancer, placebo for migraine, and anticoag for low risk AF, 20.10.2026

This week, primary care docs Gary Ferenchick, Kate Rowland, Mark Ebell and Henry Barry discuss 4 important new studies: Vitamin D for metastatic colon cancer, placebo effectiveness in adults with acute migraine, a huge RCT evaluation of Galleri multicancer early detection test, and a simpler approach to selecting which adults with AF to anticoagulate.

Episode 217: AI therapists, theta-bursts for depression, finerenone for CKD, and GLP-1s causing vision loss. 07.10.2026

This week, Henry, Kate, Gary and Mark talk about 4 great new studies: is using an AI chat therapist really that bad for youth, theta-burst stimulation for adults with major depressive disorder, finerenone in adults with CKD but not DM, and GLP-1 agonists and vision loss risk.

Episode 216: low back pain, nasal saline for URI, non-gated CTs for CAC, and statins after 70, 22.09.2026

Join our intrepid primary care experts Kate Rowland, Mark Ebell, Henry Barry and Gary Ferenchick as they tell you about 4 new primary care relevant studies: self-management and manipulation for low back pain, nasal saline for treating adults with URIs, non-gated CT scans and coronary calcium measurement, and statins after age seventy. Links: Low back pain: https://pubmed.ncbi.nlm.nih.gov/42223934/...

Episode 215: self collected HPV, AI skin cancer app, electroacupuncture for neuralgia, and asymptomatic cardiac plaque 09.09.2026

This week, primary care experts Drs. Kate Rowland, Gary Ferenchick, Mark Ebell and Henry Barry discuss 4 new studies: The post-Papanicolau era of HPV self collection, electroacupuncture for post-herpetic neuralgia, AI-based app for melanoma detection, and the onset age of silent atherosclerosis. Links: Self-collected HPV: https://pubmed.ncbi.nlm.nih.gov/42509175/ Electroacupuncture: https://pubmed...

Episode 214: hyperemesis treatment, Ca++ and Vit D, oral PCSK-9, and semaglutide for dementia (?) 27.08.2026

Primary care physicians Kate, Mark, Henry and Gary discuss 4 new studies that could change your practice: treatments for hyperemesis gravidarum, calcium and vitamin D to prevent falls and fractures in older adults, the first oral PCSK9 inhibitor, and oral semaglutide to treat dementia . The John Hickner Memorial fund at MSU: https://give.msu.edu/?sid=17374 Hyperemesis gravidarum treatments: https:...

Episode 213: dementia risk factors, COVID-19 vaccines, and shoulder MRIs 11.08.2026

This week, Kate, Gary and Mark discuss 3 new studies: whether we can do anything about modifiable risk factors for dementia, whether COVID-19 vaccines are still useful, and how to interpret abnormal shoulder MRIs.

Episode 212: preventing multimorbidity, high dose vit D, skin cancer screening, and withdrawing a GLP-1 03.08.2026

Primary care docs Kate Rowland, Mark Ebell, Henry Barry and Gary Ferenchick talk about 4 new studies: prevention of multimorbidity in people at high risk of diabetes, high-dose vitamin D in healthy older adults, whether screening for skin cancer reduces melanoma mortality, and tirzepatide withdrawal and weight maintenance .

Episode 211: semaglutide for AUD, preventing post-vax syncope, PCR panel for RTI, fluvoxamine for long-COVID 15.07.2026

Join primary care professors Mark Ebell, Kate Rowland, Gary Ferenchick and Henry Barry as they discuss 4 new studies: semaglutide for alcohol use disorder, a vibrating cool pack to prevent post vaccination syncope, PCR for 23 respiratory pathogens in primary care to reduce antibiotic use, and fluvoxamine for Long-COVID Fatigue. Links Semaglutide for AUD: https://pubmed.ncbi.nlm.nih.gov/42070571/ V...

Episode 210: screen time, stopping levothyroxine, new mRNA flu vaccine, and NAS supplements. 02.07.2026

This week primary care physicians Kate Rowland, Mark Ebell, Gary Ferenchick and Henry Barry discuss four new studies: screentime for children, discontinuing levothyroxine, a new mRNA flu vaccine from Moderna, and nicotinamide adenine dinucleotide (NAD) Supplementation for healthy aging. Links to articles: AAP screen time policy Discontinuing levothyroxine study mRNA flu vaccine from Moderna NAD su...

Episode 209: cocoa, best UTI antibiotic, LAA closure for AF, and evolocumab for primary (sort of) prevention 18.06.2026

Primary care docs Mark Ebell, Kate Rowland, Henry Barry and Gary Ferenchick tackle 4 new studies: health benefits of cocoa supplements, the best antibiotic for managing uncomplicated UTIs in women, left atrial appendage closure for AF with high bleeding or stroke risk, and evolocumab for primary (sort-of) prevention of MACE in patients with diabetes. Essential Evidence Plus: www.essentialevidencep...

Episode 208: drinks with diabetes, new Paxlovid trial, antiplatelet agents in stroke, and dietary advice from the AHA 02.06.2026

This week, primary care doctors Mark Ebell, Kate Rowland, Henry Barry and Gary Ferenchick discuss four new studies: whether water is better than diet drinks in diabetes, a new RCT of Paxlovid for COVID in contemporary patients, to switch or not to switch antiplatelet agents after a stroke, and the latest AHA 2026 dietary advice for heart health. Drinks for diabetes: ttps://pubmed.ncbi.nlm.nih.gov/...

Episode 207: AI, singing for post-partum depression, and new AHA lipid guidelines 20.05.2026

This week Kate, Mark and Henry talk about empathetic robots, mother-baby singing groups for postpartum depression, and new American College of Cardiology lipid guidelines. Indiana AFP POEMs course in French Link: https://www.iafp.org/2026ac Empathetic robots: https://pubmed.ncbi.nlm.nih.gov/41359230/ Weekly singing groups for postpartum depression: https://pubmed.ncbi.nlm.nih.gov/41087020/ ACC/AHA...

Episode 206: biomarkers for dementia, toileting, bleeding risk, and diagnosing volume overload. 06.05.2026

Join primary care faculty Gary Ferenchick, Kate Rowland, Henry Barry and Mark Ebell as they discuss 4 important new studies: the value (?) Of biomarkers in cognitive impairment, toilet training, bleeding risk with apixaban versus rivaroxaban for VTE, and diagnosing volume overload in adults  from the JAMA Rational Clinical Exam series.

Episode 205: inhaled steroid dose, titrating GLP-1s, zoster vaccine and dementia, and trusting AI 29.04.2026

This week, primary care doctors Kate, Gary, Mark and Henry discuss high vs low dose inhaled steroids for high risk patients with asthma, click based semaglutide titration to reduce GI problems, zoster vaccine and dementia risk, and whether we are trusting AI too much.  

Episode 204: lowering triglycerides, cannabinoids for pain, managing AF + stent, and lower LDL targets for CAD 14.04.2026

This week primary care physicians Kate Rowland, Mark Ebell, Gary Ferenchick and Henry Barry tackle 4 new POEM-worthy studies: new therapy for elevated triglycerides, cannabinoids for chronic pain in adults, the best antithrombotic for patients with AF + drug eluting cardiac stent, and lower versus standard LDL targets for patients with heart disease Essential Evidence Plus: https://www.essentialev...

Episode 203: melatonin for dementia, new PE guidelies, inhaled steroids for asthma 05.04.2026

This week, primary care physicians Henry Barry, Gary Ferenchick and Mark Ebell discuss several new studies: melatonin for older adults with cognitive impairment, new pulmonary embolism guidelines, and inhaled corticosteroid dosing for children and adults with asthma. Kate has the week off.

Episode 202: Repatha for prevention, baby lotions to prevent eczema, opioids for kid pain, and treatment of appendicitis 18.03.2026

This week, primary care docs Mark, Kate, Henry and Gary discuss skin lotions to prevent eczema, adding an opioid to ibuprofen for kids with acute injuries, evolocumab (Repatha) for very high risk persons, and 10 year follow-up of antibiotics vs surgery for uncomplicated appendicitis.

Episode 201: HPV collection, Tramadol, anticoag after ablation, and COVID vaccines 27.02.2026

This week, we cover a range of topics: urinary vs cervical HPV collection, the benefits and harms of Tramadol, whether patients need anticoagulation after successful ablation for afib, and the ongoing value of COVID vaccines in the omicron era. Plus a quiz: is TAVR now indicated for everyone with severe aortic stenosis? Stay tuned!

Episode 200: implant bleeding, introducing yourself, avoiding LP for infants, anticoag for AF with stroke 16.02.2026

Join primary care faculty Kate Rowland, Gary Ferenchick, Henry Barry and Mark Ebell as they discuss 4 practice changing studies: norethindrone acetate for uterine bleeding with the contraceptive implant, introducing yourself to a new patient, avoiding LPs in febrile infants, and antithrombotic strategies after ischemic stroke with AF and atherosclerosis. And an Olympic quiz!

Episode 199: GIPs, risk based breast CA screening, 1 vs 2 doses HPV vaccine, and surgery for shoulder impingement 04.02.2026

Join primary care physicians Kate Rowland, Gary Ferenchick, Henry Barry and Mark Ebell as they discuss 4 new POEMs (Patient Oriented Evidence that Matters): cardiovascular outcomes of GIPs (vs GLP), risk-based breast cancer screening (WISDOM Trial), whether a single dose of HPV vaccine is as good as two, and surgery (or not) for shoulder impingement syndrome. Plus Kate has a great Groundhog Day qu...

Episode 198: Tirzepatide, using Beers, stent for carotid stenosis, and high dose flu vaccine 22.01.2026

Join Mark, Kate, Henry and Gary as they discuss 4 new POEMs (Patient Oriented Evidence that Matters, studies with the potential to change practice): a summary of the evidence on tirzepatide (Zepbound) for weight loss, using the Beers list with your patients, high vs standard dose flu vaccine and the risk of hospitalization, and whether stent or endarterectomy are better than maximal medical therap...

Episode 197: tirzepatide for kids, new flu vaccine, bathing for eczema and beta-blockers post-MI 07.01.2026

This week, primary care physicians Kate Rowland, Mark Ebell, Gary Ferenchick and Henry Barry tackle 4 new practice changing studies (POEMs): bathing frequency for people with eczema, tirzepatide in obese children and adolescents with T2DM, a new flu vaccine, and whether beta-blockers still matter after MI.

Episode 196: Med diet, pneumonia guideline, coffee for afib, and meds for agitation in elderly 24.12.2025

Join primary care physicians Kate, Gary, Henry and Mark as they discuss 4 new POEM (Patient Oriented Evidence that Matters), chosen for their potential to change practice and improve patient outcomes: Mediterranean diet to prevent diabetes, an update to the community-acquired pneumonia guideline, coffee or decaf for afib, and safety of meds for acute agitation in the elderly. North Dakota Academy...

Episode 195: aspirin or clopidogrel, lipids and dementia, colon CA reminders 09.12.2025

Join Kate, Gary and Mark (Henry has the day off) as we discuss 3 useful new studies: colorectal cancer screening reminders, aspirin or clopidogrel for secondary prevention of CV events, and lipid lowering drugs and dementia risk

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