Mark Ebell
Primary Care Update
Four healthily skeptical primary care physicians discuss the latest in primary care medicine. Join Essential Evidence Editor Mark Ebell MD, Rush University's Kate Rowland MD, MSU Professor of Medicine Gary Ferenchick MD, and POEMs co-founder Henry Barry MD, MS for this fast-paced weekly update on evidence-based primary care.
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Episodes
Episode 185: resistant HTN tx, mirtazepine for sleep, baloxav for prevention, PRP for OA 16.07.2025 32:59
This week our intrepid primary care docs discuss 4 new POEMs: spironolactone vs amiloride for resistant hypertension, mirtazapine for insomnia in older adults, baloxivir for influenza post exposure prophylaxis, and platelet-rich plasma injections for knee osteoarthritis. We've got opinions! Show notes: Spironolactone vs amiloride for resistant hypertension: pubmed.ncbi.nlm.nih.gov/40366680/ Mi...
Episode 184: new UTI antibiotic, fibromyalgia tx, trial of an MCED, and the best time for HTN meds 02.07.2025 38:15
Join Mark, Kate, Henry and Gary as they discuss 4 new POEMs: a new and very hard to pronounce antibiotic for uncomplicated UTI, the best drugs for relieving pain in adults with fibromyalgia, a clinical trial of a multicancer detection test in asymptomatic persons, and bedtime vs morning administration of antihypertensives. Gepotidacin for uncomplicated UTI: https://pubmed.ncbi.nlm.nih.gov/38342126...
Episode 183: triple inhaler for COPD, managing pain in kids, and suzetrigine for pain 18.06.2025 26:24
This week, join Kate, Mark and Henry as they discuss all in one triple inhalers for COPD, the best medication for pain management in children and suzetrigine, a new medicine for acute pain in adults. Gary is off this week, working on his French lessons. And we add intro music! Yay!
Episode 182: atrial appendage occlusion for AF, oral semaglutide, and epidural steroidsand 04.06.2025 28:47
Join Mark, Henry, and Gary (we are Kate-less unfortunately this week) for discussion of epidural steroid injections for adults with radicular back pain, post a fib ablation management, and oral semaglutide for high-risk patients with Type 2 DM
Episode 181: wipes to prevent foot ulcer, tirzepatide efficacy, 21.05.2025 31:08
This week, Kate, Mark, Gary and Henry discuss 4 great new POEMs: foot care wipes for patients at risk of diabetic foot infection, resuming DOACS following intracerebral hemorrhage in adults with a fib, treating prediabetes with tirzepatide, and more on intermittent fasting. Show links BMJ Magic Evidence interactive review of diabetes medications. A great practice and teaching tool: https://matchit...
Episode 180: dance benefits, POCUS for clavicles, treating BV, and prehab 13.05.2025 31:13
This week, Kate, Gary, Mark and Henry chat about the health effects of dance for older adults, POCUS for diagnosing clavicular fractures, treating male partners of women with BV, and prehabilitation before elective surgery . Links: Dance for older adults: https://pubmed.ncbi.nlm.nih.gov/39480190/ POCUS for clavicle fractures: https://pubmed.ncbi.nlm.nih.gov/39626455/ Oral + topical treatment of m...
Episode 179: novel migraine tx, safety of albuterol in infants, new UTI antibiotic, and vitamin K2 for leg cramps 22.04.2025 32:06
This week join our intrepid primary care physicians Kate, Gary, Henry and Mark as they discuss 4 new studies: an experimental treatment for chronic migraines, safety of albuterol in wheezy kids under 2, oral gepotidacin for uncomplicated UTI, and vitamin K2 and Leg Cramps. Here are the links: Lukas' Fund supporting the Piedmont Athens and Grady Atlanta NICUs: https://www.lukasfund.org Essentia...
Episode 178: tapering benzos, neuro testing for athletes, vonoprazan for PUD, and zoster-dementia link 08.04.2025 34:24
This week Kate, Gary, Mark and Henry discuss discontinuation of benzodiazepines and treatment of insomnia, the value of baseline cognitive testing of college athletes, vonoprazan vs PPI for preventing and treating ulcers, and whether herpes zoster vaccine reduces dementia risk. Show links: Essential Evidence Plus: www.essentialevidenceplus.com Tapering benzos: https://pubmed.ncbi.nlm.nih.gov/39374...
Episode 177: steroids and CV risk, dementia guideline, fezolinetant for VMS, and osteoporosis screening 26.03.2025 31:11
This week Gary, Mark, Kate and Henry discuss: adverse effects from inhaled steroids in asthma, Italian dementia guideline, fezolinetant for treatment of vasomotor symptoms, and updated USPSTF recommendations for osteoporosis screening. Show notes and links: Asthma and risk of CV events: https://pubmed.ncbi.nlm.nih.gov/39088770/ GINA 2024 guidelines: https://ginasthma.org/2024-report/ Italian demen...
Episode 176: bright lights, fever in kids, new anticoagulant for AF, and antibiotics for appendicitis 12.03.2025 28:15
Join Kate, Gary, Mark and Henry as they discuss 4 new POEMs relevant to primary care: bright light therapy for non-seasonal depression, fever control in children, abelacimab for atrial fibrillation, antibiotics vs surgery in children with nonperforated appendicitis. Get all of the POEMs (a new one every day) by going to Essential Evidence Plus and subscribing. Links from today's podcast: Brigh...
Episode 175: RSV monoclonals, acupuncture for sciatica, zoledronate in low risk women, and measuring BP at home. 26.02.2025 32:41
This week, Gary, Kate, Henry and Mark discuss 4 new studies relevant to primary care practice: the effectiveness of RSV monoclonals in infants, acupuncture for sciatica associated with disk herniation, zoledronate every 5 years for low risk women, and the effect of arm position on blood pressure readings. Plus a quiz! Please see below for show notes and links: Learn more about Essential Evidence P...
Episode 174: sexual dysfunction, GLP-1 benefits, surveillance for DCIS, episodic migraine prevention 12.02.2025 31:12
Join Kate, Mark, Gary and Henry as they discuss 4 new POEMs on treatment of sexual dysfunction, the benefits and harms of GLP-1 agonists, active surveillance vs usual care for ductal carcinoma in situ, and medications to prevent episodic migraine headache. Henry mentioned AAFP's uncensored resources: www.aafp.org/family-physician/patient-care/clinical-recommendations.html www.aafp.org/family...
Episode 173: prenatal cannabis use, fluids in sickle crisis, single or dual tx for AF plus CAD, and exercise for weight loss. 03.02.2025 29:02
This week, join Kate, Mark, Gary and Henry as they discuss 4 new studies: prenatal cannabis exposure, fluid resuscitation during acute sickle crises, edoxaban or edoxaban + ASA for afib with CAD, and the impact of aerobic exercise on weight loss in adults
Episode 172: mindfulness for pain, methotrexate and resveratrol for OA, and eradicating HP 15.01.2025 23:55
Join Henry, Kate, Mark and Gary as they discuss 4 new POEMs: an RCT of mindfulness for chronic pain, use of methotrexate (huh?) for pain relief in adults with knee DJD, a new way to eradicate H., and oral resveratrol for adults with painful DJD of the knee (you know, the stuff from red wine). And a quiz: what actually are the benefits of lower BP targets? Links Mindfulness for chronic pain: htt...
Episode 171: obesity in babies, DOACs after stroke, semaglutide for OA, and thunderclap headaches 06.01.2025 28:12
This week join our intrepid team of skeptical primary care doctors as Kate, Mark, Henry and Gary discuss a web- and text-based intervention to prevent obesity in babies, the best timing of DOAC initiation after ischemic stroke in adults with atrial fibrillation, using semaglutide for knee osteoarthritis, and the differential diagnosis of thunderclap headaches. Plus the BEST quiz ever. Links: Preve...
Episode 170: yoga for incontinence, muscle relaxants for pain, maternal cannabis use, and GLP-1 v. surgery 16.12.2024 29:24
This month Kate, Mark, Gary and Henry discuss yoga for treating urinary incontinence in older women, benefits and harms of muscle relaxants for adults with chronic pain, maternal prenatal cannabis use and developmental delays, and bariatric surgery vs. glucagon-like peptide 1 receptor agonists in obese adults with T2DM. Links: Yoga for incontinence: https://pubmed.ncbi.nlm.nih.gov/39186785/ Muscle...
Episode 169: migraine, plantar fasciitis, beta-blocker duration and prostate cancer 04.12.2024 28:37
This week Mark, Kate, Gary and Henry talk about the comparative effectiveness of migraine medications, strategies for adults with plantar fascia pain, whether to continue beta-blocker use after acute MI, and the outcomes of 5-alpha reductase inhibitor use prior to prostate cancer diagnosis. Links Migraine: https://www.bmj.com/content/386/bmj-2024-080107 Plantar fasciitis: https://pubmed.ncbi.nlm.n...
Episode 168: RSV med, colonoscopy by PCP, hair loss drug, and AI for ECGs 18.11.2024 24:25
This week listen in as Kate, Mark, Gary and Henry discuss antiviral treatment for infant RSV, colonoscopy competence by specialty, oral minoxidil for hair loss in men, and artificial intelligence performance on interpreting electrocardiograms . RSV medication: https://www.nejm.org/doi/full/10.1056/NEJMoa2313551#ap2 and https://pubmed.ncbi.nlm.nih.gov/39321361/ Colonoscopy by specialty https://...
Episode 167: laughter, HP eradication, antibiotics for delirium, and MRIs of the knee 06.11.2024 27:49
Join Kate, Gary, Henry and Mark as they discuss a new therapy for dry eye syndrome, antibiotics for suspected UTI in adults with delirium, a new ACG guideline for treating H pylori, and the prevalence of knee pathology in asymptomatic adults. See below for links to the articles and other stuff: Dry eye treatment BMJ: https://www.bmj.com/content/386/bmj-2024-080474 Patient instructions: https://www...
Episode 166: vaping cessation, BP meds and dementia, SGLT-2's, and AI for melanoma 23.10.2024 29:20
Join Gary, Kate, Mark and Henry as they discuss text messages for adolescent vaping cessation, stopping BP meds in nursing home residents with dementia, the benefits of SGLT-2 inhibitors, and mobile phone app–based artificial intelligence for diagnosing melanoma. Click here for transcript, notes and links for this episode.
Episode 165: psychedelics for depression, preventing and treating influenza, and GLP-2 for...sleep apnea? 08.10.2024 34:15
It's biscuit week, oops, I mean flu week here on the Great Primary Care Update. Join our bakers, I mean POETs, as they discuss preventing influenza, treating severe influenza, psychedelics for depression, and GLP-1 agonists to treat sleep apnea of all things.
Episode 164: HTN in kids, steroids for hip OA, drugs for T2DM, and AI to develop guidelines 24.09.2024 32:38
This week, Gary, Henry, Kate and Mark discuss CV events in children with hypertension, intra-articular steroid injections in adults with hip DJD, the best drug classes for treating adults with T2DM, and AI supported development of practice guideline questions. And a quiz, and two sports stories from Henry!
Episode 163: salt substitutes, VR apps for pain, multivitamins, and vitamin D 11.09.2024 29:24
This week join Kate, Mark, Henry and Gary for a discussion of the cardiovascular benefits of salt substitutes, using virtual reality for cancer-related pain, whether multivitamins reduce mortality, and if and when to recommend vitamin D supplements.
Episode 162: PREVENT risk score, UTI prognosis, sinusitis treatment, and biomarkers for SDAT 29.08.2024 33:53
This week, Kate, Mark, Gary and Henry tackle 4 new studies: the updated PREVENT cardiovascular disease risk calculators from the AHA, long-term consequences of UTIs in children, antibiotics for sinusitis in kids, and biomarkers to diagnose Alzheimer’s disease
Episode 161: Antibiotics for CAP, melatonin for delirium, screening for lung disease, and seizures after COVID vaccine 15.08.2024 30:53
This week, join Kate, Gary, Mark and Henry as they discuss screening asymptomatic people for COPD and asthma, the rate of new onset seizures after COVID vaccination, choosing the best oral antibiotic for mild to moderate CAP, and a trail of melatonin for delirium in older, hospitalized adults
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