Modern Healthspan

Dr. Valter Longo explains how fasting-mimicking diets make cancer cells vulnerable to treatment while protecting healthy tissue, plus the clinical evidence, safety protocols, and why oncologists remain skeptical. Dr. Valter Longo, author of "Fasting Cancer," breaks down decades of research on using fasting-mimicking diets (FMD) alongside conventional cancer therapies. Cancer cannot be st...

Dr. Luigi Ferrucci reveals what 60 years of Baltimore Longitudinal Study data shows about aging, inflammation, mitochondria, and the biomarkers that predict your health trajectory. In this conversation, Dr. Luigi Ferrucci, Scientific Director of the National Institute on Aging and director of the Baltimore Longitudinal Study of Aging, shares insights from the longest-running scientific study of hu...

Dr. DanPardi explains why creatine supplementation may help preserve cognitivefunction during sleep deprivation, aging, and high mental demand, plus thespecific dosing strategies most people miss.   In thisconversation, Dr. Dan Pardi breaks down the emerging science of creatine forbrain health. While creatine is famous for athletic performance, new researchshows it may help maintain cognitive func...

Dr. Allen Taylor spent 40 years at Tufts discovering how diet affects vision. Learn why high glycemic foods accelerate macular degeneration and cataracts—and what you can do to protect your eyes. Dr. Allen Taylor directed the Laboratory for Nutrition and Vision Research at Tufts University for four decades, pioneering groundbreaking discoveries about how nutrition impacts age-related eye diseases....

Your ferritin test doesn't measure what you think. Dr. Douglas Kell explains iron dysregulation, dormant microbes, and his controversial theory about chronic disease Dr. Douglas Kell, systems biologist at the University of Liverpool, presents his research on iron dysregulation and its potential role in chronic inflammatory diseases. In this conversation, he explains why ferritin in blood is ac...

Dr. Eric Plaisance explains how exogenous ketones may provide fasting benefits without dietary restriction - the hormetic effects of mimicking starvation while fed. Plus: ketone salts vs esters, his personal protocol, and why performance claims don't hold up. Dr. Eric Plaisance, Associate Professor at University of Alabama Birmingham, has spent over a decade studying exogenous ketone esters. H...

Dr. Mary Newport shares groundbreaking research analyzing cholesterol profiles across 40 years of studies, challenging conventional wisdom about saturated fat and heart health. We discuss her findings on MCT oil for brain health, the 288 caregiver reports showing cognitive improvements, and practical protocols for using coconut oil and ketones. Dr. Mary Newport, physician and Alzheimer's resea...

DESCRIPTION Leading hairrestoration surgeon Dr. Alan Bauman reveals the science behind hair loss,graying, and the evidence-based treatments that actually work—from medicationsto regenerative therapies. Dr. Alan Baumanis a board-certified hair restoration physician who has treated over 30,000patients and performed 14,000+ hair transplants in his 28-year career. In thisconversation, we explore the b...

Dr. Henry Mahncke reveals how an NIH-funded study showed brain training reversed brain aging markers by 10 years, why speed-based training is uniquely effective, and the future of brain health interventions. Dr. Henry Mahncke, CEO of Posit Science and creator of BrainHQ, discusses the groundbreaking INHANCE study that used PET scans to show brain training can reverse brain aging by 10 years. In th...

Dr. John Cramer, 92-year-old nuclear physicist, discusses participating in the first mitochondrial transplant trial for aging and his longevity theory. Dr. John Cramer is a 92-year-old emeritus professor at the University of Washington who has spent decades researching nuclear physics and quantum mechanics. Now, he's turned his attention to longevity, and he's not just theorizing. Dr. Cram...

Mayo Clinic's Dr. Sundeep Khosler discusses findings from the first major randomized controlled trial of senolytics in humans, revealing why cellular aging varies dramatically between individuals and what this means for longevity interventions. Dr. Sundeep Khosler, a physician-researcher at the Mayo Clinic, leads some of the first human clinical trials testing senolytics for aging and age-rela...

Professor Charles Brenner challenges the NAD decline myth and reveals why nicotinamide riboside (NR) works for metabolic stress, not aging. Learn about the Northwestern trial showing NR improved walking speed in peripheral artery disease while metformin failed, eight clinical trials proving anti-inflammatory effects, and why popular biomarker tests are measuring the wrong thing. In this conversati...

Could a decline in "plasmalogens" be a missing link in Alzheimer's and aging? Dr. Peter Meikle reveals why this critical brain lipid drops as we age and the surprising foods that might help restore it. In this interview, we sit down with Dr. Peter Meikle, Head of the Metabolomics Laboratory at the Baker Heart and Diabetes Institute, to explore the critical role of plasmalogens in hum...

Genetics professor Dr. Jan Vijg explains how DNA damage causes aging and why human lifespan may be limited to 115 years. Learn about the 100,000 DNA hits your cells take daily, breakthrough research on the DREAM gene complex that could slow mutation accumulation, and whether we can extend maximum lifespan. In this conversation, Dr. Jan Vijg, Professor and Chair of Genetics at Albert Einstein Colle...

Holistic dentist Dr. Namrata Patel reveals how your oral microbiome predicts heart disease, Alzheimer's, and cancer 10-13 years before symptoms appear. Learn about saliva testing, the bacteria that cause systemic inflammation, why tongue exercises reduce sleep apnea 30%, and the daily protocol that protects your healthspan. In this conversation, holistic dentist Dr. Namrata Patel explains how...

Clinical psychologist Dr. Lloyd Glauberman reveals why smart, motivated people struggle to maintain healthy habits - and the 3 things you knew as an infant that could transform your health. Learn about lifestyle intelligence, the metabolism changes after 40, and why sustaining change is harder than starting. In this conversation, clinical psychologist Dr. Lloyd Glauberman explains the hidden psych...

Duke Professor reveals how 90-year-olds tripled their muscle strength in just 10 weeks - and why we've been measuring muscle mass wrong for decades. Dr. William Evans explains the revolutionary new test that predicts disability, mortality, and even Alzheimer's risk. Learn the exact protocols for maintaining muscle mass as you age, the truth about protein requirements, and why your doctor i...

44% of supplements FAIL testing! Dr. Glenn, Head of Science at SuppCo, reveals which supplements don't contain what they say, how to spot red flags, and why even expensive brands might be lying about what's in the bottle. Learn the 3 essential rules before buying ANY supplement. Think your supplements contain what they claim? Think again. Dr. Glenn, Head of Science at SuppCo, drops a bombs...

Methylene blue was the first synthetic medicine ever created. 140 years later, we're discovering it might be one of the most powerful tools for brain health and longevity. Here's what the research actually shows. Dr. Francisco Gonzalez-Lima has spent decades researching methylene blue, the first synthetic medicine in history. In this conversation, he explains how this unique compound enhan...

Hearing loss isn't just about your ears—it's about your brain. Dr. Ben Thompson reveals how treating hearing loss can reduce cognitive decline by 48% and shares breakthrough protocols for tinnitus recovery that actually work. Audiologist Dr. Ben Thompson explains the critical connection between hearing health and cognitive function, discussing the landmark ACHIEVE study that showed hearing...

NAD+ Anti-Aging Breakthrough: How This Molecule Could Reverse Aging and Treat Alzheimer's Disease | Clinical Trial Results from Leading Longevity Researcher Dr. Evandro Fang Some links are affiliate links so we will earn a commission when they are used to purchase products. Dr. Evandro Fang from the University of Oslo reveals groundbreaking research on NAD+ and its role in combating aging and...

Could a simple supplement that bodybuilders use to build muscle actually help fight Alzheimer's disease? Dr. Matthew Taylor from the University of Kansas reveals surprising results from her groundbreaking clinical trial testing high-dose creatine in Alzheimer's patients In this episode, Dr. Matthew Taylor discusses his pioneering research on creatine supplementation for Alzheimer's dis...

A potential functional cure for HIV could be just months away from human trials. Dr. Lanna reveals how her company Sentcell is using cellular rejuvenation to eliminate HIV reservoirs—and the surprising anti-aging benefits that come with it. n this groundbreaking interview, Dr. Lanna, founder and CEO of Sentcell, explains how his team has developed a revolutionary approach to HIV treatment that cou...

When someone's LDL cholesterol hits 574 mg/dL, doctors typically expect the worst. But what if everything we think we know about cholesterol and heart disease risk is incomplete? In this episode, I sit down with researchers Nick Norwitz, Adrian Soto-Mota, and Dave Feldman to discuss their groundbreaking study on lean mass hyperresponders - a rare population who develop extremely high LDL chole...

Senescent cells were supposed to be the "easy" target in aging research—clear them out and extend healthspan. But new research reveals the field is far more complex than anyone imagined, with major clinical trial setbacks forcing scientists to completely rethink their approach. Some links are affiliate links so we will earn a commission when they are used to purchase products. In this co...