Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast

This is a not-to-be-missed episode!  Dr. Dempsey discusses the use of GLP-1 medications for MCAS, including her most recent observations and recommendations.  This is a follow-up to Dr. Dempsey's free online GLP-1 Masterclass , which covers all the basics.  If you have questions for Dr. Dempsey about mast cells and related topics, you can send them to research@standinguptopots.org . Dr. Dempsey's...

Dr. Melanie Stein, ND  is a licensed Naturopathic Physician in Portland, Oregon and a recognized leader in Cell Membrane Therapy for the treatment of complex and chronic illness. She specializes in restoring health at the cellular level—repairing and revitalizing cell membranes to improve energy production, enhance detoxification, and restore healthy communication between cells. In this episode, s...

Dr. Dempsey is always looking for new ways to help her complex patients.  In this episode Dr. Dempsey discusses how she incorporates treatments with Methylene Blue, peptides, and the Nanovi breathing device.  For each one she explains what it is, how it works, the risks and benefits, who is a good candidate, and more. More information about Dr. Tania Dempsey and her clinic can be found at https://...

Dr. Casey Kelley is Board Certified in family and integrative medicine, teaches on the faculty of the Northwestern Medical School, and her care is informed by her own past experience having complex chronic invisible illness.  Now she treats some of the very toughest cases, including Lyme, POTS, PANS/PANDAS, MCAS and more.  In this episode she and Dr. Dempsey discuss cutting-edge treatment approach...

Dr. Spiritos is double board certified in gastroenterologist and internal medicine, and specializes in IBS, gut motility, POTS and the complex conditions and symptoms that go along with it.  He and Dr. Dempsey discuss IBS, parasites, SIBO, CD117 staining, GLP-1 drugs for MCAS, his treatment approach, some promising news on the awareness front, and much more.   Dr. Spiritos's website is here Dr. De...

One of the most common questions we get from listeners is about the novel treatments that Dr. Dempsey mentions, such as therapeutic plasmapheresis exchange (or apheresis), SOT, ozone therapy, UV light blood irradiation and more.  In this episode she discusses each treatment:  What it is, how it works, the risks and benefits, who is a good candidate, and more. More information about Dr. Tania Demps...

This is a not-to-be-missed episode for anyone interested in brain inflammation.   Dr. Eboni Cornish, M.D. is Associate Medical Director at Amen Clinics, Fellow and Treasurer of the Board for the International Lyme and Associated Diseases Society (ILADS). With research training at the National Institutes of Health as a Howard Hughes Medical Fellow, she is nationally recognized for her evidence-base...

Dr. Jill Krapf is a Board-Certified OB/GYN who specializes in genitopelvic pain and skin conditions, is founder of the Center for Vulvovaginal Disorders and co-author of the book When Sex Hurts: Understanding and Healing Pelvic Pain .  She is a wealth of knowledge and with Dr. Dempsey they discuss the mechanisms behind these disorders, treatments, plus their findings about how mast cells may be in...

Dr. Greg Plotnikoff is a thought leader in dysautonomia/MCAS and complex chronic illness and in this episode he is freshly returned from giving two presentations at the Dysautonomia International Conference.  He and Dr. Dempsey discuss what he learned and what he is currently excited/hopeful about, including new data about hypermobility as a potential underlying factor and a theory about how thiam...

MCAS doesn't ignore the nether-regions, so in this episode, Dr. Dempsey discusses symptoms and treatments in the genitourinary and surrounding areas, including some novel uses of antihistamines and mast cell stabilizers, as described in this research article.   She also answers listener questions about hormones, hormone replacement, reactions to ultrasounds and ultrasound gel (this is the gel with...

Dr. Todd Maderis is a naturopathic physician in Marin, CA, who began his career in environmental medicine and now specializes in helping complex patients by searching for the root causes of their illness.  He and Dr. Dempsey discuss their hypotheses about how and why some patients can get so sick, their favorite newer tests and treatments -- including genetic testing, SOT, phosphatidylcholine -- a...

This is an excellent discussion for patients and practitioners alike who are interested in the connections between MCAS, POTS, venous compression, pelvic venous disorder, and MALS.   Cardiologist Dr. Cutchins and Dr. Tania Dempsey share tons of information plus their latest thinking on how to treat patients with these complex presentations, including an in-depth conversation about how MCAS patient...

Dr. Anna Cabeca started her career as a researcher and busy physician, until her own fertility issues drove her to search the world over for better solutions for women's sexual health.  In this interview with Dr. Dempsey we learn about hormones, symptoms, treatments, natural alternatives, that vaginal health is important for overall health, and much more. Dr. Cabeca's website is here:   https://dr...

Dr. Donna Kirchoff is an integrative developmental and behavioral pediatrician who works with children who have complex conditions, often involving MCAS, autism and other neuroinflammatory conditions like PANS and PANDAS.  In this episode she and Dr. Dempsey discuss the role of mast cells in these conditions and what can be done to help these young patients. Dr. Kirchoff's website is here. Dr. Dem...

Gillian Ehrlich's NeuroVeda Clinic in Seattle treats complex patients with a wide variety of treatments including peptides, Ayurvedic medicine, diet and nutrition, imaging, mind-shifting therapeutics, plasmapheresis, and more.  In this episode, Dr. Tania Dempsey interviews Gillian about her Ayurvedic approach and also her experiences with plasmapheresis.   More information about Gillian and her cl...

Dr. Ruscio is a thought leader, expert, clinician and researcher (and podcaster!) specializing in gut health and SIBO - small intestinal bacterial overgrowth.  In this episode, he and Dr. Tania Dempsey discuss how gut health issues like SIBO can drive MCAS, plus Dr. Ruscio's approach to testing and treatment.  This is a great conversation between top clinicians, full of practical tips for patients...

Joseph Anew is now the picture of health and fitness, but as a young man he was severely injured and received a dior diagnosis. When conventional treatments failed, he moved to a tropical beach to live out his few remaining days.  What happened next has been the basis for his great fitness and career helping others to overcome health challenges, feel their best, and perform beyond expectations.  J...

In this episode Dr. Dempsey explains how hormones can affect mast cells and vice verse, especially when it comes to puberty, menarche, pregnancy, and menopause.   More information about Dr. Tania Dempsey and her practice can be found at https://drtaniadempsey.com/ .  If you liked this episode, we hope you will click subscribe so that you don't miss an episode. If you are so moved, donations are ac...

Michael Rubino is an air quality expert, environmental wellness advocate and President of Change the Air Foundation .  He is widely known as the trusted source for mold remediation expertise.  In this episode Dr. Dempsey and Michael discuss how to avoid mold in your environment, even if you don't have the means to move out of a moldy home. Here is the mold spore video discussed in this episode.  ...

Dr. Dempsey explains the facts on mold as a trigger for mast cells, including symptoms, preferred tests, treatments, resources for remediation and expectations for recovery.  This is a not-to-be-missed episode since -- as we learn in this episode -- nearly everyone has likely had exposure to the types of mold that can be problematic.  Dr. Dempsey is a mold expert and serves on the Medical Board of...

In this 3rd Q&A session with the amazing Dr. Dempsey she goes deep on infections as a trigger for MCAS:  How they're transmitted, symptoms, testing, treatment, and expectations for recovery.  This is a not-to-be-missed episode since -- as we learn in this episode -- nearly everyone has likely had exposure to the types of infection that can be at play. More information about Dr. Tania Dempsey a...

This is a not-to-be-missed episode between two incredible physicians: Dr. Jill is a highly sought-after leader in functional medicine and a survivor of cancer/crohne's/MCAS.  She and Dr. Dempsey compare approaches to treating MCAS, discuss Dr. Jill's new book and film, and describe some lesser-known treatment strategies like methylene blue with red light therapy. Connect with Dr. Jill at the links...

Dr. Dempsey interviews breast surgeon Dr. Eva Nagy about her important new findings just published about evidence of mast cell activation in Breast Implant Illness.  Dr. Nagy is the world's leading surgeon for explant surgery and previously covered Breast Implant illness in episode 184. Dr. Nagy's website is here and her  new publication is here. Dr. Dempseys website can be found here. If you like...

Nobody answers your MCAS questions as rapid-fire as Dr. Dempsey!  She's back to answer listener questions, addressing the topics of anaphylaxis, Epi-Pens, difficult blood draws, itching, what to do when otherwise healthy or important activities cause flares, and so much more. More information about Dr. Tania Dempsey can be found at https://drtaniadempsey.com/ .  If you liked this episode, we hope...

Dr. Kelly McCann is a leading educator on MCAS and related complex disease, with her online seminars and an approach that combines functional, integrative and environmental medicine.  Drs Dempsey and McCann have a far-reaching conversation about MCAS strategies and factors ranging from mindset to muscle testing to genetic predisposition for breaking down fibrinogen blood clots. More information ab...