Tania Dempsey, MD with Jill Brook, MA
Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast
Each episode is a deep dive on Mast Cell Activation Syndrome (MCAS) with a top physician, researcher or other expert who specializes in treating patients with MCAS. Hosted by Johns-Hopkins-trained world renowned specialist Tania Dempsey, MD, we take a practical approach to helping doctors and patients better manage MCAS. We cover the symptoms, testing, diagnosis, treatment, challenges, practical strategies, common comorbidities (e.g., POTS, hypermobility spectrum disorders, ME/CFS, autoimmunity, GI dysmotility), latest research findings and clinical pearls. These episodes are a monthly feature...
Author
Tania Dempsey, MD with Jill Brook, MA
Category
Podcast website
Latest episode
May 30, 2026
Where to listen?
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Episodes
Mold-induced Illness is Treatable with Dr. Neil Nathan 28.05.2024 57:32
Dr. Neil Nathan is the leading expert on mold and mycotoxin illness, and in this episode he and Dr. Tania Dempsey discuss how mold can cause chronic illness and how to treat it. They also discuss Dr. Nathan's new book, The Sensitive Patient's Healing Guide, available here from Amazon . Dr. Nathan's other books and resources, plus information about working him, can be found at https://neilnathan...
Vote now to raise awareness and funds with (the very strong) Dr. Tania Dempsey 13.05.2024 24:28
Dr. Tania Dempsey shares her passion (and some tips) for bodybuilding, because she has been nominated to be on the cover of Muscle and Fitness Hers magazine! If she is voted to be on the cover, it will raise awareness of complex conditions like POTS/MCAS/hypermobility spectrum disorder, AND Dr. Dempsey would donate the $20,000 prize to the documentary in progress about the Triad. You can vote h...
Mast cells driving Dysautonomia (& much more) with Mast Cell Master Dr. Theoharides 16.04.2024 1:02:09
Dr. Theoharides is among the world's top mast cell researchers and speaks with Dr. Dempsey about his recent article reviewing how mast cells may drive dysautonomia and vice verse. They also cover a range of topics from mast cells' diversity to their role in autism, most effective mast cell stabilizers and much more. This episode is packed with advanced mast cell information. Dr. Theoharides has...
Dr. Dempsey answers listener questions 26.03.2024 50:35
Dr. Dempsey answers questions about MCAS and depression/anxiety/fatigue/brain fog; physical triggers; Kounis Syndrome; whether it's worth it to allow "small" flares in the name of pizza or other small joys; treatments such as stenting for venous compression; how long to try each antihistamine; and much more. More information about Dr. Tania Dempsey can be found at https://drtaniadempsey.com/ . If...
Unraveling Complexity in Chronic Illness with Dr. David Kaufman 12.03.2024 54:49
Dr. David Kaufman is renowned for working with the most complex patients and for his podcast on Patreon, Unraveled: Understanding Medical Complexity . He and Dr. Dempsey discuss the role of MCAS in ME/CFS and other complex disorders and how he starts unraveling these complex clusters of conditions. You can learn more about Dr. Kaufman and his practice here . You can learn more about Dr. Dempsey...
MCAS, POTS & Pediatric Cardiology with Dr. Jeffrey Boris 06.02.2024 56:39
Dr. Dempsey interviews pediatric cardiologist Dr. Jeffrey Boris about the Triad (MCAS, POTS and hypermobility syndromes) in his pediatric population. As an avid researcher and data analyst, Dr. Boris is always a wealth of knowledge on latest findings and yet-unpublished trends and hypotheses. The doctors also exchange interesting observations about MCAS and cholesterol, PCOS, and much more. You...
Behind the Scenes of the Triad Documentary with the Producers/Doctors: A crossover episode 11.01.2024 53:03
We have the entire medical/production team of 5 physician/researchers to give us an update and behind-the-scenes look at the documentary they are making about the trifecta of MCAS, dysautonomia/POTS, and hypermobility spectrum disorders. We hear from doctors Tania Dempsey, Larry Afrin, Linda Bluestein, Lawrence Kinsella and Leonard Weinstock, along with patient Jill Brook, to hear how filming is...
MCAS & Breast Implant Illness with Breast Surgeon Eva Nagy, MD 02.01.2024 1:14:29
Dr. Dempsey interviews Dr. Eva Nagy, a world-renowned breast surgeon experienced in all sorts of breast surgeries, who has developed special interest and skill in treating breast implant illness (BII), which she believes can be related to mast cell activation syndrome (MCAS). Dr. Nagy describes BII, how she removes problem implants, and the effects this can have on a wide range of symptoms. You c...
Psychiatric Manifestations of MCAS with Dr. Janet Settle 05.12.2023 45:10
Dr. Settle is a psychiatrist who believes that mast cell activation is responsible for some symptoms of anxiety, depression, bipolar disorder type II and others. She treats MCAS as a way to stabilize both mast cells and their emotional state. You can learn more about Dr. Settle and her practice here . You can learn more about Dr. Dempsey and her practice here . You can read the transcript for this...
Mast Cells, Pain and Hypermobility with Dr. Linda Bluestein 08.11.2023 50:03
MCAS expert Dr. Bluestein is an anesthesiologist and pain specialist focusing on hypermobility and its associated pain syndromes. Having EDS and her own pain, she discusses the use of opioids, ketamine, pain programs in this population, and much more! You can learn more about Dr. Bluestein and her practice and podcast here . You can learn more about Dr. Dempsey and her practice here . You can read...
Documentary on The Triad with Dr. Leonard Weinstock 08.11.2023 19:10
Dr. Weinstock and Dr. Dempsey are spearheading the creation of a documentary about MCAS, POTS, and EDS. Still in the planning stages, this documentary intends to educate medical professionals and the general public. We hope that it will help raise awareness! Link to the LDN Research Trust: https://ldnresearchtrust.org/mast-cell-activation-syndrome-documentary You can read the transcript for this e...
Cardiac manifestations of MCAS with Dr. Andrew Maxwell 08.11.2023 52:26
Treating MCAS, POTS, and Long COVID can be difficult, and physicians must attack from various angles to get patients feeling better. Dr. Maxwell walks us through his thinking and how MCAS is linked to POTS and Long COVID. This episode is a must-listen for patients and practitioners alike. You can read the transcript for this episode here: http://tinyurl.com/potscast159 If you liked this episode,...
GI Manifestations of MCAS with Dr. Leonard Weinstock 08.11.2023 44:24
Dr. Weinstock, a gastroenterologist and leading expert on MCAS, discusses mast cells in the context of the GI tract. Bloating, gas, SIBO, SIFO, and IBS are all discussed in this episode. In addition, he shares how he prescribes LDN for his patients. There is a ton of great information in this episode for patients and practitioners alike! You can read the transcript for this episode here: https://...
Dr. Lawrence Afrin on MCAS Diagnostic Criteria “Consensus-2” 08.11.2023 55:10
Dr. Afrin, a world expert in all things mast cell, talks in depth about issues with the first MCAS "consensus" statement and the need for a second MCAS consensus statement so that patients can be treated even if their lab tests don't show an elevation of tryptase levels. This opens the diagnostic door to many additional patients so that they can get the treatment that they need. You can read the t...
Diagnosis & Treatment of MCAS with Dr. Tania Dempsey 08.11.2023 38:04
Dr. Dempsey shares her experience in both diagnosing and treating people with MCAS. She always looks for POTS and orthostatic symptoms during diagnosis, as these are often comorbid disorders. Antihistamines and other major medications commonly used to treat MCAS are also discussed. You can learn more about Dr. Dempsey and her practice here . You can read the transcript for this episode here: http...
Introduction to mast cells and mast cell activation syndrome (MCAS) with Dr. Tania Dempsey 08.11.2023 42:43
Dr. Dempsey is helping us to launch a new series within the POTScast focusing on all things mast cells. These cells are an important part of the immune system and are found throughout the body. Learn more about what happens with these cells malfunction! You can learn more about Dr. Dempsey and her practice here . You can read the transcript for this episode here: https://tinyurl.com/potscast115 P...
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