Less of You: Life on Semaglutide & Tirzepatide

Kami goes off her GLP-1, stops her thyroid meds, and gains back 25 lbs. After 3 months of Eva being angry for no reason, it turns out she just needs hormones. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.  Are you confronting the same challenges? We’d love to hear...

Kami runs out of weight loss meds during the holidays, gains 10 pounds, and blames the dryer for shrinking her clothes. Eva overschedules everything, battles inconsistent clothing sizes at fancy events, and gets unsolicited body size comments at work. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past se...

Eva gets ghosted in the middle of an important situation and spirals for a day. Kami stops her meds and finds out what it feels like to be hungry again after two years. Check out Murderland: Crime and Bloodlust in the Time of Serial Killers Shop Shapermint Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our pa...

After sewing a quilt on the floor, Kami’s back goes out. After kicking a dumbbell, her foot goes out too. New compounded meds including glycine and B12 make a noticeable dent in Eva’s persistent body aches. A 3-week pause in medication to get a tooth pulled has a surprising effect.  We deconstruct our instincts to soften bad news by bribing our children with treats like McDonald’s. Listen to the n...

While working on a project about addiction, Eva realizes she went from drinking and smoking to a food addiction. But she’s not even sure what her “thing” is now, which is… a little terrifying.  Meanwhile, Kami loses some weight—not exactly from a wellness plan, but courtesy of stress and no sleep. Hey, a win’s a win. Eva + Kami are two old-ish moms with little kids confronting our reasons for bein...

If you want to keep your meds a secret from someone you live with, here’s how we would keep it secret.  Kami’s cat, Leonardo Von Flouffe, makes his debut.  Eva remembers why she was rejected from the United States Marine Corps (really).  Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm...

How does being hungry seem to interfere with every activity?  One child can’t stop eating sugar, the other starts yelling about being hungry while sitting in the 4th row at Mary Poppins, and some mom guilt creeps in over kolaches, portion sizes, and generational food baggage.  Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutid...

Ashley tried everything. She tried all the diets: Weight Watchers, Nutrisystem, SlimFast, Houston Methodist Medical Weight Management program. Even after a gastric sleeve, her weight climbed back up to 320 lbs. Going to therapy for binge eating was good, but still didn’t help her lose weight. In 2024, exhausted from trying to lose weight yet again, she thought, “screw it, if I’m going to be fat, w...

Kami forgets to track her calories and take her meds. Eva sends her daughter to camp and Kami remembers getting left behind at camp at age 12, back when there were no cell phones.  Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.  Are you confronting the same challen...

Eva gained a few pounds back and got a muffin top. Kami vs. insurance: It should not be this hard to get sleep apnea treatment. Yep, you can get a payment plan for weight loss meds. Because results shouldn’t depend on your wallet crying. Learn more about PatientFi ! Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roast...

Kami broke her foot, and can’t move. Eva ate 4 dark chocolate mini eggs and got sick (4 eggs, not 4 bags of eggs). We beat the question “Don’t you feel totally different now?” to death.  Kami SW 250, CW 198, GW 150? Eva SW 280, CW 184, GW 170 Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sar...

Kami finally busted through the plateau, now hovering at 200 at officially down 50 lbs. Eva’s creeping toward 100 lbs lost,  and had to try on size 8 jeans for the first time since 5th grade.  For the record, yes, we’ve lost weight, but we’re still the same people on the inside. Stop asking if we “feel great.” We love that we’re inspiring people to take the plunge! Shoutout to @jennpurrr on Instag...

In this special bonus episode, an excerpt from a conversation with Los Angeles Addictionologist Dr. Jason Giles about the potential for GLP-1s as a treatment for substance abuse, explaining their impact on cravings and brain chemistry. Dr. Giles candidly shares his own journey with addiction, how he overcame it, and how it led him to specialize in addiction medicine. Learn more about Los Angeles a...

The Debra returns with a progress update and fills in for Kami, who’s out with the flu.  She started at 168, now at 154, aiming for 150. It took almost two months before the scale even moved, but she stuck with it. Hear Debra’s thoughtful tips if you’re thinking about using a GLP-1 to lose weight, and why you should be careful who you tell. Eva + Kami are two old-ish moms with little kids confront...

Kami stalls at 203 and wonders if it’s time for a higher dose to make it to one-derland.  Eva shares a jaw-dropping “before” pic from August 2021 after eating at Paula Deen’s while in Nashville.  Meet Eva’s doctor, Austin plastic surgeon Dr. Johnny Franco Kami SW 250, CW 203, GW 150? Eva SW 280, CW 189, GW Just Overweight  Eva + Kami are two old-ish moms with little kids confronting our reasons fo...

New to semaglutide or tirzepatide? Here are our tips for what to expect when you are just getting started.   We survived the mountains of Christmas food and Eva let a wardrobe stylist give her closet a full makeover. Kami SW 250, CW 205, GW 150? Eva SW 280, CW 194, GW 170? Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide an...

Thanksgiving chaos update, questionable ingredients brought by in-laws, a recurrence of rear-end issues, and how Eva got peer-pressured into tucking in a shirt. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.  Are you confronting the same challenges? We’d love to he...

Eva has lost 90 lbs, the equivalent of 9 gallons of paint according to the Lose It! app. It’s Kami’s birthday and she makes big plans for the night. An old friend reaches out at the end of her 2nd month of semaglutide injections with questions about stalled progress.  Kami SW 250, CW 207, GW 150? Eva SW 280, CW 189, GW 170? Eva + Kami are two old-ish moms with little kids confronting our reasons f...

Still blowing money on groceries we end up tossing, planning the menu for Thanksgiving but not planning to binge eat, and excited to have full houses.  Somehow 100 people subscribed to us on YouTube. We don’t know why, but thanks! Here’s where to subscribe if you haven’t already. Kami SW 250, CW 211, GW 150? Eva SW 280, CW 192, GW 175 Eva + Kami are two old-ish moms with little kids confronting ou...

Eva feels fat and to feel better tries on the largest jeans she ever owned (size 20W). Kami gives a fire recovery update while wearing a fox costume for Halloween.  Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.  Are you confronting the same challenges? We’d love t...

Kami’s 92-year-old neighbor’s house burns down, the 2nd fire in a year of serving on the HOA board. Eva forgets a full order of groceries in the car on a 90-degree day. Life keeps happening, the only difference is that now we forget to eat.  Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarc...

Weigh yourself every day. Don’t weigh yourself every day. Only weigh yourself at the weigh-in. Weigh yourself in the morning after you go to the bathroom. Always weigh yourself at the same time every day. Take off your shoes. Don’t wear jeans to the weigh-in. Don’t drink a lot of water on your weigh-in day. Weigh in on Friday so you can cheat on the weekend. Go to your weigh-in in the morning and...

Eva's 30 year high school reunion approaches with the same worries as high school, including what to wear and who will I know?  Kami’s in full freak-out mode after watching the Oprah special on AI and hearing about scammers using AI to mimic voices. Then there’s the whole "Oatzempic" thing blowing up TikTok with oat-based smoothies, which sound disgusting. Kami promises to be brave and try this we...

Kami’s mom Debra joins with her own skinny shot update after 8 weeks. Kami’s endocrinologist breaks up with her because her thyroid is perfect. Eva worries about a compounded tirzepatide becoming unavailable and attempts to stockpile shots.  The viral cookbook: What to Cook When You Don't Feel Like Cooking by Caroline Chambers Eva + Kami are two old-ish moms with little kids confronting our reason...

Because Cassie Layne, FNP, knows the struggle of dealing with weight firsthand, she’s dedicated to making health and wellness accessible for everyone.  In just over two years, she’s helped over 5,000 people from across all of Indiana reach their weight loss goals with affordable semaglutide for just $98 a month.  One of those people is our very own Kami, the co-host of Less of You!  Cassie shares...