JACC Author Interviews

In this episode of Behind the Science, host Adith Arun sits down with Dr. Evangelos Oikonomou to discuss groundbreaking research published in JACC: "Early Prediction of Heart Failure from Routine Cardiac CT Using Radiomic Phenotyping of Epicardial Fat." Dr. Oikonomou walks us through how AI-powered radiomic analysis of epicardial adipose tissue, the fat layer directly surrounding the heart, can se...

In this episode of Behind the Science, we explore how coronary artery calcium scoring improves cardiovascular risk assessment in patients with elevated lipoprotein(a). This multicohort study highlights how Lp(a) and CAC serve as independent predictors of ASCVD and how combining both tools enhances risk stratification in clinical practice. Learn how calcium scoring can help identify higher risk ind...

Listen in to JACC's perspective on our newest research, published on June 19 and featuring co-authors Adith Arun, BS, Clyde W. Yancy, MD, MSc. We present readers with another update in our Data Report Series, evaluating trends in excess cardiovascular mortality among Black Americans compared with White Americans from 2000 to 2024 and persistent disparities in outcomes. While modest improvements we...

Dr. Aaysha Cader, Social Media editor for JACC Interventions and Dr. Chao Gao discuss the pre-specified subgroup analysis of the REC-CAGEFREE I trial: Drug-Coated Balloon Angioplasty vs Drug-Eluting Stents in Noncomplex Coronary Bifurcation Lesions.

Dr. Aaysha Cader, Social Media editor for JACC Interventions and Dr. Antoinette Neylon discuss the randomised KISS trial: Side Branch Additional Treatment for Coronary Bifurcation Lesion Revascularization.

Join us for the latest Behind the Science discussion, featuring an article published in JACC's May 12 focus issue on hypertension. Adith Arun, MD, joins author William B. White, MD, as they discuss a phase 2 randomized trial of the NPR1 agonist XXB750 in patients with resistant hypertension. The interview highlights the study, a randomized, double-blind, placebo-controlled trial of 4 doses of XXB7...

In this interview in JACC's May 12 issue focusing on hypertension, JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, MACC speaks with first author Samantha S. O'Connell, MS, MD, as they discuss a comprehensive global analysis of hypertension trends from 2000 to 2020, drawing on data from nearly 300 population-based studies across 119 countries. The findings show that while awareness and treatment h...

Can artificial intelligence really adjudicate heart attacks, strokes, and cardiovascular deaths in clinical trials? Adith Arun sits down with Jonathan W. Cunningham to discuss cutting-edge research using AI to automate major adverse cardiovascular event (MACE) adjudication—one of the most expensive and time‑consuming parts of global clinical trials. They explore how AI models review extensive medi...

At ACC.26, JACC Editor-in-Chief Dr. Harlan Krumholz speaks with Dr. Wayne Batchelor about the ALERT Trial, published in JACC. Their discussion explores how automated EHR-based clinician alerts can help identify patients with significant valvular heart disease who may otherwise be overlooked, improving timely referral, heart team evaluation, and valve intervention. The conversation also covers the...

In a panel at ACC.26, this video features Dr. Clyde Yancy of Northwestern University in conversation with Ambarish Pandey, Lauren Eberly, Jennifer Cluett, and Oluwabunmi Ogugngbe, exploring how social determinants of health can be studied as measurable variables in clinical research. The discussion highlights innovative trials examining "food as medicine," community-based nutrition interventions,...

Recorded on the final day of ACC.26, this video features an unscripted conversation between Dr. Ami Bhatt, Chief Innovation Officer at the American College of Cardiology, and Dr. Harlan Krumholz, Editor-in-Chief of JACC. They reflect on the rapid expansion of artificial intelligence in cardiology, discussing its impact on clinical workflows, research, education, guideline development, and patient...

Midventricular obstruction in hypertrophic cardiomyopathy (HCM) is rare—but clinically significant. In this episode of Behind the Science, Adith Arun and Alexander Schulz, MD break down new JACC findings showing why midventricular obstructive HCM should be recognized as a distinct, higher‑risk phenotype, rather than grouped with non‑obstructive disease. Through a focused discussion of echocardiogr...

JACC is pleased to present an interview focusing on two papers presented at CRT. Listen in to JACC Executive Associate Editor Karthik Murugiah, MD, FACC, speak with authors Martin Frydland, MD, PhD, and Helle Søholm, MD, PhD, on their paired DOBERMANN-D and DOBERMANN-T trial research. The trials tested early low-dose dobutamine and the IL 6 inhibitor tocilizumab in high-risk STEMI patients to prev...

In this author interview, JACC Associate Editor Seng Chan You, MD, speaks with Bamba Gaye, MD, PhD, about his team's newly published study examining African representation in randomized clinical trials (RCTs) across major general medical and cardiovascular journals from 2019–2024. Listen in to this behind-the-scenes analysis of this important study addressing the profound underrepresentation of Af...

In this featured JACC article, author Naveed Sattar, MD, speaks with deputy editor Erica Spatz, MD, MHS, FACC on how to design trials for the increasing field of obesity medicines. Listen in as they discuss a roadmap for next generation cardiometabolic outcome trials in obesity, emphasizing the need to move beyond traditional MACE focused endpoints toward broader, patient centered outcomes. The in...

In this episode of Behind the Science, Adith Arun sits down with Rishi Shah to uncover the surprising realities behind new JACC data reports on U.S. cardiovascular health. They break down why major gaps in exercise, sleep, medication adherence, and access still persist—despite gains in insurance coverage. Using NHIS data from 2019–2024, Adith and Rishi explore the stubborn income driven disparitie...

On Behind the Science, host Adith Arun interviews Dr. Rishi Wadhera and Dr. Sanket Dhruva, lead authors of the new JACC Stats Cardiovascular Statistics Report. They discuss why the report was created, what the latest data reveal about hypertension, diabetes, obesity, and cardiometabolic risk, and why younger adults are facing rising cardiovascular burdens. The conversation also explores geographic...

The ACHD Guideline gets expert perspectives in JACC's February 24 mini-focus issue. In this interview, join JACC Consultant Sitaram M. Emani, MD, speak with commentary author Emile A. Bacha, MD, FACC, about the maturation of the Adult Congenital Heart Disease (ACHD) specialty following the release of new AHA/ACC guidelines. Dr. Bacha emphasizes the necessity of a multidisciplinary "team sport" app...

Learn more about the ACHD guideline in JACC's February 24 issue. In our latest interview, JACC Consultant Yonatan Buber, MD, FACC joins author Patrick T O'Gara, MD, MACC to discuss key insights from the 2025 Adult Congenital Heart Disease guidelines and how they intersect with the 2020 ACC/AHA Valvular Heart Disease guidelines. The conversation highlights the importance of multidisciplinary, share...

Early diagnosis in transthyretin cardiac amyloidosis (ATTR CM) matters more than ever. Adith Arun talks with Dr. Ahmad Masri about key findings from the ATTRIBUTE CM phase 3 trial on acoramidis, what recurrent event analyses reveal, and why delays in suspicion, diagnosis, or treatment can meaningfully impact outcomes. They also explore challenges in clinical pathways, updates in the therapeutic la...

JACC's February 24 issue is a mini-spotlight issue on the ACHD Guidelines. In this discussion, Lidija B. McGrath, MD, provides additional early career perspective on the 2025 Adult Congenital Heart Disease (ACHD) guidelines. In the interview with JACC Consultant Carla P. Rodriguez-Monserrate, MD, they highlight the value of the guideline as a practical decision aid for clinical care, education, an...

JACC's February 24 issue highlights the ACC/AHA ACHD guideline. In this in-depth interview, JACC Executive Associate Editor Emily Bucholz, MD, PhD, MPH, speaks with JACC Associate Editor Anne Marie Valente, MD, FACC, on her piece co-written with Carole A. Warnes, MD, FACC. In the interview and viewpoint, they discuss key updates in the adult congenital heart disease guidelines, emphasizing expande...

On February 24, JACC's mini spotlight issue brings readers a focused look on the ACHD guideline. This interview with JACC Consultant Yuli Y. Kim, MD, interviewing authors Babar S. Hasan MBBS and Raman Krishna Kumar MD, DM, takes a look at adapting care for patients with ACHD in low to middle income countries. What do clinicians do in a healthcare environment where diagnostic imaging, advanced inte...

In this ACHD Guideline Spotlight interview, author Curt J. Daniels, MD, and JACC Consultant Anitra W. Romfh, MD discuss the growing adult congenital heart disease population in the U.S., projected to exceed 2 million by 2050. His viewpoint, published in JACC's February 24 issue, highlights the urgent need for more providers, comprehensive care centers, and innovative models like hub-and-spoke netw...

In JACC's February 17 issue on Women's Heart Health. JACC Deputy Editor Erica Spatz, MD, joins author and JACC Associate Editor Michael Honigberg, MD, FACC, to discuss the need to rethink cholesterol management in women by moving beyond short term, age driven risk calculators toward a life course approach that accounts for cumulative exposure to atherogenic lipoproteins. His piece in our focus iss...