ID:IOTS - Infectious Disease Insight Of Two Specialists

Did you think the  evidence base for Stenotrophomonas was bad? Well allow  us to introduce you to Burkholderia cepacia complex! BCC is pretty niche but a key pathogen in people living with cystic fibrosis. We talk through the (very) limited treatment options and evidence base for this difficult bug. Prep notes for this episode here: https://idiots.notion.site/68-Burkholderia-cepacia-complex-7bba8a...

Callum and Jame wrap up their thoughts on the recent FIS conference.  Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes for completed episodes can be found here (Not all episodes have prep notes). If you are enjoying the podcast please leave a review on your preferred podcast app! 

Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.html Mentioned in episode: ESCMID brain abscess guidelines: https://www.sciencedirect.com/science/article/pii/S1198743X23003993# ORAL study protocol: https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-0...

Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.html Mentioned in episode: UCHL HLH protocol and referral details: https://www.uclh.nhs.uk/our-services/find-service/medical-specialties-1/hlh-service SNAP trial: https://www.snaptrial.com.au/ SNAP trial email: snap...

In this episode Jame and Callum are joined by Louis, host of the let's talk micro podcast. Listen in for a discussion on what a Biomedical Scientist is and how to become one. We explore the key details that clinicians need to add to their specimen request details; and ponder how laboratory managers can make this easier for clinicians. How to request a test: https://global.oup.com/academic/pro...

Ready for some startling Steno statistics? In this big 1-parter, Callum & Jame go through Stenotrophomonas maltophilia, from start to finish.  Unlike Pseudomonas & Acinetobacter, Steno is much less commonly seen outside of ITU & the immunocompromised; but when it shows up you have to know what you’re doing. Luckily for you, there’s basically only 2 treatments! (In Europe: you’ll see wh...

In Part 2 of our episodes on Acinetobacter we talk abouit resistance, and then do a deep dive into the evidence base for the management of CRAB: Carbapenem-Resistant Acinetobacter Baumanii-calcoaceticus complex. Do have a look at the prep notes for this episode if you want more information on Acinetobacter. Links to podcasts mentioned in this episode ID:IOTS Episode 41: Bugs Without Borders Febril...

In this episode, Callum and Jame go over the second big family of nonfermentors, Acinetobacter. In part 1 we talk about the organisms themselves, risk factors, clinical syndromes and diagnostics before talking a little about treatment.  In Part 2 (released next week) we’ll talk about Carbapenem-Resistant Acinetobacter Baumanii-calcoaceticus (CRAB), and resistance mechanisms in general.  Support th...

In part 2, we discuss the limited treatment options for pseudomonas infection, some wildcard options and the resistance mechanisms that make Pseudomonas such a tricky bugger to treat!  Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes for completed episodes can be found here (Not all episodes have prep...

It was a long time coming, but it’s here. Jame and Callum set off on our mini-series, Nobbling the Nonfermentors, starting with an introduction to glucose-nonfermenting organisms before moving on to the biggie: Pseudomonas aeruginosa!  Part 2 next week covers treatment of Pseudomonas, including a deep dive into Pseudomonas resistance mechanisms. Stay tuned! Support the show Support us on:  Patreon...

Jame and Callum were delighted to be invited as guests to the podcast Microbe Mail by host Vindana (Vin) Chibabhai. Check out the Microbe Mail podcast: https://microbemail.captivate.fm/  @microbemail We discuss how bactericidal and bacteriostatic are defined, what the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) are and why this isn't as simple as it fir...

Jame and Callum are together in person to talk about the importance of keeping your house in order. Being an infection specialist does not automatically make you an antimicrobial steward. We reflect on some challenges to being an antimicrobial steward  when practising infection medicine The choosing wisely campaign mentioned by Jame: https://www.choosingwisely.org/ A course on Antimicrobial Stewar...

We were delighted to be joined by Dr Anastasia "Tash" Theodosiou to talk about breastfeeding, antibiotics and the risks of antibiotic harm to mum and baby. Tash is an infectious diseases/medical microbiology trainee, host of the HelloMicro blog and has volunteered as a Breastfeeding Peer Supporter. *Note the NICE guidelines have been updated and do not recommend trimethoprim in any stage...

2 years. It’s been a hell of a ride. Here’s to 2 more.  Links from this episode:  KASIC 1-page evidence-summary on aminopenicillins for resistant enterococcal UTIs:  https://bit.ly/44CtNnq AUDIENCE SURVEY!!!  Please do fill this out, it would mean a lot to us: https://forms.gle/aCq2djmfKPjA6tkMA .  Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  http...

This is the urine antibiotic drug penetrance you never knew you wanted. Jame might be prouder of this than his own children. Callum, as you will be able to tell, remains indifferent*. Figure out which antibiotics you can trust, and which you can't. Use the table in the prep notes and links to win arguments, justify treating 'resistant' organisms in the urine, BREAK HEARTS - you name...

Catheter-associated UTI: Callum’s nemesis. His white whale. His Sauron. His favourite rant.  Want to know how favourite? Listen on! Show notes for this episode here Useful links (see show notes for more) RICAT study Chlorhexidine meatal cleaning Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes for comp...

Loyal Listeners! Free yourselves from this outdated language! Emancipate your hospitals from 'Escalation antibiotics'! In today's episode, Callum and Jame rant for 35 minutes about how we talk about changing therapy, and how talk of escalating antibiotics leads to desire for 'big gun' antibiotics. Apologies for Callum's audio quality on this episode. We'd apologi...

The title says it all. We're going back to the lab for this discussion. Join Jame and Callum as they have an in depth discussion about the nature of urine culture. Prep notes for this episode available here .  Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes for completed episodes can be found her...

Ever wondered what a clinical scientist is or how to become one? Are you a clinical scientist and looking to sit the FRCPath exams? Join Jame and Callum as they talk to Phillipa Burns and Vicki Fleming about their experiences in preparing for their FRCPath exams in microbiology. Here are some of the resources mentioned during this episode: Colour atlas of bacteriology UK Reference laboratory manua...

Welcome to the party pal! The penicillin allergy assessment and delabelling party, that is. Callum takes Jame through the latest evidence base in antibiotic allergy in general, and beta lactam allergy assessment and management in particular.  Links:  PENFAST Score paper:  Trubiano JA et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule. doi: 10.1001/jamainternmed.2020.0...

Join Callum with guests Morgan Evans, Olivia Hawkes and Katy Hill for the final(?) part of the ECCMID 2023 highlights ECCMID sessions discussed: - Antimicrobial stewardship poster session - Ethical dilemmas with antimicrobial therapy - The value of diagnostic information for antimicrobial stewardship - Tick borne diseases and prevention Music: https://pixabay.com/music/acoustic-group-outrigger-144...

Join Callum with guests Andrew Seaton, Marianna Avellar, Hannah Pymont, Eva Garmendia, Sanjay Patel and Dave Hettle live from ECCMID 2023. ECCMID sessions discussed: - Fairytales or reality, checking some eminence paradigms for treatment of severe infections - Neglected tropical skin diseases - Non-canonical approaches to treatment of infections - Paediatric interactive cases: dilemmas for the mic...

Join Callum with Guests Robert Ball, Kelly Bicknell & Rob Read live from ECCMID 2023.  ECCMID sessions discussed: Antibiotic stewardship for urinary tract infections: challenges and opportunities Viral Infection in immunosuppressed patients: what is new? Responsible publishing in CM/ID Secondary haemophagocytic lymphohistiocytosis and infectious diseases Review article on HLH: https://www.ncbi...

Callum is reunited with Jame following their separation at ECCMID 2023. Callum shares some highlights including Archaea and their role in human health, Digitalisation within the microbiology lab and the ESCMID/IDSA interview Links to publications on Archaea: https://www.moissleichingerlab.com/projects/ https://twitter.com/chmoei?lang=en Digitalisation and machine learning in microbiology presentat...

Jame rides solo today, going over the beta-lactamase inhibitors, old and new, how to think about them and when to use them in anger.  New Show notes format! Available at https://idiots.notion.site/Beta-Lactamase-Inhibitors-f9999b6a4867470996a31c53e661b5ac NB: For now all old show notes are available in the usual Onedrive folder.  Support the show Support us on:  Patreon:  https://www.patreon.com/c...