ID:IOTS - Infectious Disease Insight Of Two Specialists

Jame and Callum are joined by the one and only Sara Dong of Febrile fame to look at the American Board of Internal Medicine's Infectious Disease Certification Exam.  Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes for completed episodes can be found here (Not all episodes have prep notes). If you...

Jame and Callum are joined by semi-recent FRCPath Microbiology part 1 exam passers Callum and Jame to discuss how best to prepare for this exam. This exam is sat by all infection trainees in the UK, as well as other health care professionals working in infection such as clinical scientists.  Full revision resources notes available in the linked OneDrive folder below (if you can't access it le...

Jame and Callum are joined by Vin from Microbe Mail to discuss the management of Difficult to Treat Resistance (DTR) Gram negative infections in South Africa. If you haven't already check out Microbe mail for a high quality infection podcast linking the lab and clinical management.... wait that sounds familiar! Vin is a associate Professor in Clinical Microbiology at the University of the Wit...

Jame and Callum are joined by recent FRCPath Microbiology part 2 exam passers Olly and Rob to discuss how best to prepare for the exam. This is the final exam required to qualify as a medical/clinical microbiologist in the UK.  Full revision resources notes available on this notion page: https://idiots.notion.site/40-FRCPath-part-2-microbiology-78288c756979431fa82c6191ab3622f3 Support the show Sup...

It's time for journal club! Jame and Callum discuss community acquired pneumonia treatment and a paper from 2021 which examines shorter duration therapy for patients responding to therapy. Paper discussed: Dinh, Aurélien et al. “Discontinuing β-lactam treatment after 3 days for patients with community-acquired pneumonia in non-critical care wards (PTC): a double-blind, randomised, placebo-con...

In this episode as requested on twitter (sort of),  Callum & Jame compare and contrast Gram positive & negative bacteraemia. Happy new year! Please also see our older episode on bloodstream infection: www.buzzsprout.com/1782416/9162105-5-back-to-bacteraemia SABATO trial details here:  https://twitter.com/sebpoule/status/1518496524552056833?s=46&t=Dre0YLRm_gwnKQ8OakDarw Support the show...

This Christmas, Jame shares a tale of woe: the rise and fall of Plazomicin, a hapless victim of antibiotic market forces. The conversation then proceeds/degenerates into a discussion of the economics of Antimicrobials in general, with a focus on the ‘Netflix’ model being piloted in the UK.   WE’LL BE BACK NEXT YEAR SEE YOU THEN Support the show Support us on:  Patreon:  https://www.patreon.com/cw/...

Join Jame and Callum as they take a deep dive into urinalysis, a commonly (mis)used test for UTI (and other conditions). This test put you into murky waters when used clinically and we hope to give some information to avoid being a pisse prophet. Some sources referred to in this episode: NICE Clinical knowledge summary SMI 41: Investigation of urine Summary article of PPV and NPV for urinalysis: -...

Callum and Jame discuss the HACEK organisms (apart from Haemophilus which we discussed in episode 32).  Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes for completed episodes can be found here (Not all episodes have prep notes). If you are enjoying the podcast please leave a review on your preferred p...

An atypical episode about pneumonia. Callum and Jame discuss their pet peeves.  Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes for completed episodes can be found here (Not all episodes have prep notes). If you are enjoying the podcast please leave a review on your preferred podcast app! 

Callum and Jame talk about everyone's favourite antibiotic class that covers Staph, Pseudomonas and Gram negatives, is predominantly renally excreted and isn't a quinolone, the aminoglycosides. We go over classification, mechanism of action, spectrum, resistance mechanisms, PK/PD, penetrance to various tissues, toxicity, and dosing.  This is a companion piece to our star appearance on Fe...

Join Jame and Callum as they talk you through Haemophilus spp. Turns out that Haemophilus influenzae isn't the cause of Influenza. We answer some questions such as: What are X and V? Suggestions and comments to idiotspodcasting@gmail.com or @IDiots_pod If you are enjoying the podcast please leave a review on your preferred podcast app! Feel like giving back? Donations of caffeine gratefully r...

Join Jame and Callum as they discuss the two titans of diarrhoea, Salmonella and Shigella. Who knew Salmonella species were so complex? Jame explains something that will SHOCK you about Shigella (maybe). Suggestions and comments to idiotspodcasting@gmail.com or @IDiots_pod If you are enjoying the podcast please leave a review on your preferred podcast app! Feel like giving back? Donations of caffe...

Yersinia. Not very important today, very very important in the past! Callum and Jame talk through the medically important Yersinia species, and how to treat them.  Links:  CDC page for treatment of plague:  https://www.cdc.gov/plague/healthcare/clinicians.html UK HSA SMI 21: ID of Yersinia Species https://www.gov.uk/government/publications/smi-id-21-identification-of-yersinia-species-from-faeces T...

Join Jame and Callum and they discuss some of the other Enterobacterales Gram negatives. Particularly breaking down them into their families and into Lactose fermenters and non-fermenters. Jame has a small breakdown around our Twitter handle near the end. Comments suggestions and criticisms to idiotspodcasting@gmail.com or @IDiots_pod Some lists: Chromosomal AmpC Carriers (high-risk): HECK YES · ...

Join Jame as he continues to talks through the ESCMID and IDSA treatment of Multi Drug Resistant Gram negative guidelines/guidance. Callum listens and occasionally asks a question! Jame is so passionate on this subject that we have split the episode into two parts. ECDC guidelines ·          https://onlinelibrary.wiley.com/doi/full/10.1111/j.1469-0691.2011.03570.x ·          https://www.ecdc.europ...

Join Jame as he talks through the ESCMID and IDSA treatment of Multi Drug Resistant Gram negative guidelines/guidance. Callum listens and occasionally asks a question! Jame is so passionate on this subject that we have split the episode into two parts. ECDC guidelines ·          https://onlinelibrary.wiley.com/doi/full/10.1111/j.1469-0691.2011.03570.x ·          https://www.ecdc.europa.eu/en/news-...

ID:IOTS is 1 year old today! Jame and Callum have a short chat about the the podcast, why we started and where we’re going. Of course, the real ID:IOTS are the friends we made along the way… If you want to send us cake email idiotspodcasting@gmail.com Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes fo...

Back after a summer break, Jame and Callum discuss the fascinating machine that is the MALDI-TOF. Matrix Assisted Laser Desorption Ionisation Time Of Flight mass spectrometry. We discuss the basics of how it functions, its application in the lab and some pros and cons of its use along with what the future may hold. Here are some relevant videos and papers: - Exciting video of MALDI-TOF https://www...

Join Jame and Callum as they discussion all things beta lactamase including ESBL, AmpC and Carbapenemases.  We talk through classification systems, patterns of resistance and some methods of detection.  Some resources we found helpful: Summary of beta lactamase classification: https://microbeonline.com/betalactamase-classification/ Summary of AmpC: https://www.idstewardship.com/heck-yes-get-amped-...

Callum and Jame provide an overview of the Carbapenem class of antibiotics discussing: what they are; their spectrum of action (looking in particular at what they don't cover); resistance; how to use them; and side effects. This site has a useful summary of the new formulation of carbapenems and their spectra: http://www.microbiologynutsandbolts.co.uk/the-bug-blog/new-sweets-on-the-market-but...

Jame and Callum continue their discuss of the Enterobacterales, looking at Klebsiella spp. with focused discussion on some microbiological history, K1 syndrome, and the pharmacokinetics of antimicrobials for endophthalmitis. For the graphic Jame suggested look at Figure 4 in this paper:  https://academic.oup.com/femsre/article/41/3/252/3830265 Suggestions and comments to idiotspodcasting@gmail.com...

Jame and Callum have put this off for far too long... we start exploring the Gram negative bacilli by considering Enterobacterales in general and then discussing E. coli. We focus particularly on the gastrointestinal syndromes causes by different pathogenic strains of E. coli. Did you ever wonder what "coliforms" on a culture result meant - hopefully now you will find out! Support the sh...

In this episode Jame and Callum discuss other Beta-lactam antibiotics: aztreonam, temocillin and pivmecillinam... with some substantial tangents into C. difficle and carbapenems.  Send suggestions to idiotspodcasting@gmail.com Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes for completed episodes can...

In this episode Jame and Callum talk through the two most medically important Gram negative cocci: Neisseria meningitidis and Neisseria gonorrhoeae. Send suggestions to idiotspodcasting@gmail.com Support the show Support us on:  Patreon:  https://www.patreon.com/cw/IDIOTS_pod BuyMeACoffee:  https://www.buymeacoffee.com/idiotspod Prep notes for completed episodes can be found here (Not all episodes...