NephJC Team
Freely Filtered, a NephJC Podcast
Twice monthly (aspirational) recap of the NephJC journal club. NephJC reviews the most important manuscripts which are driving nephrology forward and improving our understanding of the kidney.
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Episodes
Freely Filtered 045: Salt Substitution and Stroke Study (SSaSS) 09.05.2022 1:09:24
The Filtrate: Joel Topf Joshua Waitzman Nayan Arora Jennie Lin Sophia Ambruso Special Guest: Paul A Welling Editor: Sophia Ambruso Show Notes: NephJC Summary on SSaSS Paul Welling’s tweetorial on the potassium switch The 2016 Canadian Hypertension guidelines were the first to suggest adding potassium: Hypertension Canada's 2016 Canadian Hypertension Education Program Guidelines for Blood Pressure...
Freely Filtered 044: Pigs on the Wing: Xenotransplantation 11.04.2022 1:03:12
The Filtrate: Joel Topf Joshua Waitzman Nayan Arora Jordy Cohen Special Guest: Josh Mezrich Editor: Nayan Arora Show Notes: When Death Becomes Life: Notes from a Transplant Surgeon. Amazon Am J Transplant 2022 Jan 20. doi: 10.1111/ajt.16930. PMID: 35049121 Coverage on NephJC First transplant of a pig into a human. NYU transplant. Keith Reemtsma’s experience with chimpanzees transplantation: https:...
Freely Filtered 043: NephMadness and Animal House 19.03.2022 1:00:40
The Filtrate: Joel Topf Joshua Waitzman Nayan Arora Sophia Ambruso Jordy Cohen Special Guest: Kelly Hyndman Editor: Joel Topf PodCrawl Monday, March 14: The Curbsiders An Internal Medicine Podcast…for the Internist. This episode will focus on the Cardiorenal region with Game Maker , Joel Topf @Kidney_Boy , and Selection Committee Member, Sadiya Kha...
Freely Filtered 042: Nephrin Antibodies Cause Minimal Change Disease. Wait...What? 27.02.2022 1:17:58
The Filtrate: Joel Topf Jennie Lin Joshua Waitzman Nayan Arora Sophia Ambruso Special Guest: Astrid Weins ( @AstridWeins ) renal pathologist at the Brigham and Woman’s Hospital and Harvard Medical School Editor: Nayan Aurora Show Notes: Summary of minimal change disease according to the orthodoxy : Light microscopy of renal biopsy specimens from patients with MCD shows minimal to no change; howeve...
Freely Filtered 041: Top Nephrology Stories of 2021 21.02.2022 50:26
The Filtrate: Joel Topf Swapnil Hiremath Matt Sparks Editor: Joel Topf Show Notes: The 2010 RFN Top Nephrology Stories The 2021 NephJC Top Nephrology Stories Number 10: AKIKI AKIKI 2 in The Lancet AKIKI 2 in NephJC AKIKI 2 on Freely Filtered Number 9: Effect of Salt Substitution on Cardiovascular Events and Death The Salt Substitute and Stroke Study (SSaSS) in the NEJM The Salt Substitute and Stro...
Freely Filtered 040: Double CLICK for BP control in CKD stage 4 25.12.2021 1:13:51
The Filtrate: Joel Topf Swapnil Hiremath Jennie Lin (who was only there because her plans got boxed by covid) Jordy Cohen Josh Waitzman Special Guest: Rajiv Agarwal ( @AgarwalRajivMD ) Editor: Joel Topf Show Notes: NephJC discussion of CLICK: http://www.nephjc.com/news/click4chlorthalidone CLICK Visual abstract: http://www.nephjc.com/news/2021/12/7/the-click-visual-abstract Hawthorne effect: https...
Freely Filtered 039: The First Annual ASN #KidneyWk Draft 21.11.2021 1:10:18
The Filtrate: Joel Topf Swapnil Hiremath Nayan Arora Jennie Lin Sophie Ambruso Editor Joel Topf Show Notes: Sign Up for NephSim Nephrons. Deadline 11/30. https://nephsim.com/nephsim-nephrons/ The Draft Board except for Swapnil’s picks because…Calvin Ball: https://docs.google.com/document/d/1Unk_27uqTpMGXrOyrxbI-2csKg2W_qnbbN7IE3wZY_Y/edit?usp=sharing Calvinball per the Calvin and Hobbes Wiki : Cal...
Freely Filtered 038: AURORA1, a new treatment for Lupus Nephritis 23.10.2021 1:27:11
The Filtrate: Joel Topf Swapnil Hiremath Nayan Arora Jennie Lin Joshua Waitzman Special Guests Alfred Kim assistant Professor at Washington University, director of the lupus clinic. Receives support from Arena Pharmaceuticals, manufacturer of volcloosporin, or at least he did before this episode aired. Dawn Castor assistant professor at The University of Louisville School of Medicine. She is on th...
Freely Filtered 037: The first Guideline Draft: KDIGO Hypertension Guidelines 25.07.2021 1:30:49
The Filtrate: Joel Topf Swapnil Hiremath Nayan Arora Sophie Ambruso Joshua Weisman Editor Joel Topf Show Notes: Soccer star Christian Eriksen 'was gone' after on-field cardiac arrest, doctor says ( NBC News ) 120-sided Die. This was covered in Wired Magazine. Respect. https://www.wired.com/2016/05/mathematical-challenge-of-designing-the-worlds-most-complex-120-sided-dice/ Nephrologists that played...
Freely Filtered 036: AKIKI-2, How soon is now? 13.06.2021 1:24:30
The Filtrate: Joel Topf Swapnil Hiremath Nayan Arora Sophie Ambruso And special guests: Jay L Koyner, Professor of Medicine, University of Chicago Sarah Faubel, Professor of Medicine, University of Colorado Editor Nayan Arora Show Notes: It was Kidney 360, not Kidney Medicine. Here is the study I was thinking of: https://kidney360.asnjournals.org/content/2/1/33 SNL Five-Timers Club: https://www.yo...
Freely Filtered 029: Belimumab for lupus nephritis 15.02.2021 1:09:12
The Filtrate: Matt Sparks Jennie Lin Samira Farouk Joel Topf Swapnil Hiremath And two special guests: Dawn J. Caster , Assistant Professor at University of Louisville Alfred Kim , Assistant Professor of Medicine at Washington University ( Twitter ) Show Notes: NephJC coverage of the trial: The Bliss trial In the NEJM: https://www.nejm.org/doi/full/10.1056/NEJMoa2001180 Turtles all the way down: ht...
Freely Filtered 028: Finerenone for diabetic kidney disease 25.12.2020 1:02:27
The Filtrate: Swapnil Hiremath Samira Farouk Matt Sparks Joel Topf Jennie Lin And two special guests: Katherine Tuttle Clinical Professor Division of Nephrology, Medical & Scientific Director, Providence Medical Research Center/Sacred Heart Center, Professor of Basic Medical Sciences, WWAMI Program Washington State Universityendocrinologist and nephrologist at the University of Washington Ian...
Freely Filtered 027: Long and deep on the KDIGO Diabetes Guidelines 29.11.2020 1:33:16
The Filtrate: Swapnil Hiremath Samira Farouk Matt Sparks Joel Topf Jennie Lin And two special guests: Katherine Tuttle Clinical Professor Division of Nephrology, Medical & Scientific Director, Providence Medical Research Center/Sacred Heart Center, Professor of Basic Medical Sciences, WWAMI Program Washington State Universityendocrinologist and nephrologist at the University of Washington Ian...
Freely Filtered 026: Interventional Nephrology meet NephJC, NephJC meet Interventional Nephrology 06.11.2020 1:05:58
The Filtrate: Swapnil Hiremath Samira Farouk Matt Sparks Joel Topf And two special guests: Vandana Dua Niyyar , Professor of Medicine at Emory University and the president elect of American Society of Diagnostic and Interventional Nephrology . Wears lead. Sophia Ambruso , assistant professor and nephrologist at the University of Colorado. Show Notes: Drug-Coated Balloons for Dysfunctional Dialysis...
Freely Filtered 025: Making sense of albuminuria, proteinuria, and the dipstick 21.09.2020 59:15
The Filtrate: Matt Sparks Joel Topf Swapnil Hiremath Jennie Lin Jordy Cohen And two special guests: Morgan Grams , study author. Talar Kharadjian , nephrology fellow UC San Diego Show Notes: History of albuminuria from Matt’s opening monolog: https://academic.oup.com/ndt/article/18/7/1281/1809803 Microalbuminuria As A Predictor Of Clinical Nephropathy In Insulin-Dependent Diabetes Mellitus in the...
Freely Filtered 024: STARRT me up! 01.09.2020 1:11:13
The Filtrate: Matt Sparks Joel Topf Swapnil Hiremath COI: he was a sub-investigator on STARRT Jennie Lin And two special guests: Dr. Jay Koyner of the University of Chicago and #NephBBQ fame. Anitha Vijayan , professor of medicine at Wash U in St Louis Show Notes: The STARRT-AKI trial acronym is: Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury Matt sugges...
Freely Filtered 023: Race and Estimated GFR 20.08.2020 1:15:59
The Filtrate: Matt Sparks Joel Topf Swapnil Hiremath Samira Farouk Jennie Lin And three special guests: Carina Seah a second year MD PhD student Mt Sinai who led the initiative to remove race from the eGFR formulas Poyan Mehr , founder of GlomCon and author of this post on the use of race in eGFR estimating formulas. Deidra Crews Professor of Medicine and researcher in health disparities. Show Not...
Freely Filtered 022: Uric Acid faces the Music. 28.07.2020 1:15:58
The Filtrate: Joel Topf Swapnil Hiremath Samira Farouk And special guests: Katalin Susztak, Professor of Medicine Perlman School of Medicine, University of Pennsylvania. @KSusztak Show Notes: CKD-FIX: Effects of Allopurinol on the Progression of Chronic Kidney Disease PERL: Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes Coverage at NephJC: Effects of Allopurinol on th...
Freely Filtered 021: Aldosteronism is everywhere 14.07.2020 48:15
The Filtrate: Joel Topf Swapnil Hiremath Samira Farouk Matt Sparks Jordy Cohen And special guests: Brian Byrd , a cardiologist investigating aldosteronism at the University of Michigan and Susan Steigerwalt , a nephrologist and hypertension specialist who unfortunately due to technical problems largely was cut out of this episode 😢. The Study: The Unrecognized Prevalence of Primary Aldosteronism...
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