Freely Filtered, a NephJC Podcast

The Filtrate: Joel Topf Swapnil Hiremath Samira Farouk Matt Sparks And special guests: Sadiya Kahn a heart failure specialist at Northwestern University. @HeartDocSadiya and Paul Welling a professor of medicine and nephrology at Johns Hopkins. @PAWellingMD Show Notes: The Study: https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.120.045691 Coverage at NephJC: http://www.nephjc.com/news/sgl...

The Filtrate: Joel Topf Swapnil Hiremath Matt Sparks And special guests: Joshua Waitzman , third year nephrology fellow at Beth Israel Harold “Harv” Feldman. Editor in Chief at AJKD and national study chair of CRIC and principal investigator of the Scientific and Data Coordinating Center of the CRIC Study. https://www.dbei.med.upenn.edu/bio/harold-i-feldman-md-msce Show Notes: CRIC: Chronic Renal...

The Filtrate: Joel Topf Swapnil Hiremath Samira Farouk Jennie Lin Matt Sparks And special guests: David J. Cohen : Professor of Medicine at the University of Missouri-Kansas City and Director of Cardiovascular Research at Saint Luke’s Mid America Heart Institute. In addition, he is Medical Director of the Medical Economics and Technology Assessment Group at Mid America Heart Institute. He was prev...

The Filtrate: Joel Topf Swapnil Hiremath Samira Farouk Jennie Lin Matt Sparks And special guests: Agnes Fozo : John L. Shapiro Chair of Pathology at Vanderbilt University and on Twitter: https://twitter.com/AgnesFogo Hua Su: Professor of Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Osama El Shamy : Home Therapy Fellow at Mount Sinai...

Cast: Joel Topf Swapnil Hiremath Samira Farouk Jennie Lin Matt Sparks And special guest Joshua Waitz Martin Pollak: http://www.nasonline.org/member-directory/members/20033579.html Josh Waitz @jwaitz 100 Days of COVID-19: https://www.voanews.com/episode/100-days-covid-19-4236811 MinTac: http://www.nephjc.com/news/mintac My magical experience with minimal change disease. This is not the actual tweet...

Loeb’s Laws of Medicine or Loeb’s Rules of Therapeutics Robert Frederick Loeb ( March 14, 1895-October 21, 1973 ) was a famous American Physician who provided some very simple common sense approach to treating patients know as: 1. If what you are doing is doing good, keep doing it. 2. If what you are doing is not doing good, stop doing it. 3. If you do not know what to do, do nothing. 4. Never mak...

NephJC’s COVID-19 and the Kidney Patient Cast: Joel Topf Swapnil Hiremath Samira Farouk Jennie Lin Matt Sparks Show Notes: The NephJC Page on ACE2 and COVID-19 Nature Letter showing AER2’s central role in lung injury (in mice). This was SARS from 2005. Losartan RCT in COVID-19; University of Minnesota: Outpatient NCT04311177 Inpatient NCT04312009 France's health ministry says NSAIDs may be bad in...

Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis Summary on NephJC Cast: Joel Topf Swapnil Hiremath Samira Farouk Jennie Lin Jordy Cohen Show Notes: 55th ERS-EDTA Congress, late breaking and high impact trials . June 2018 The CJASN Review recommended by Jennie MEPEX study C5a antagonist, Avacopan in ANCA-Associated Vasculitis The fragility index as described in JAMA Surgery...

Just the dudes gathered to talk about the JAMA Internal Medicine Meta Analysis on Gadolinium in CKD stage 4 and 5. Risk of Nephrogenic Systemic Fibrosis in Patients With Stage 4 or 5 Chronic Kidney Disease Receiving a Group II Gadolinium-Based Contrast AgentA Systematic Review and Meta-analysis. Summary on NephJC Cast: Joel Topf Swapnil Hiremath Matt Sparks Show Notes: Swap has a disclosure! He wa...

Cast: Joel Topf Jennie Lin Swapnil Hiremath Matt Sparks Show Notes: The NephJC discussion can be found here . The study was published in the NEJM . NephJC summary of the AJKD systematic review of uremic pruritus Atul Gawande on itching. Pinnacle Mountain Comprehensive review on toxicodendron dermatitis: poison ivy, oak, and sumac . KIDNEYcon Tom Oates 12 days of Poems on Twitter

Cast: Joel Topf Jennie Lin Swapnil Hiremath Matt Sparks Samira Farouk Show Notes: Pathway 2 Trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)00257-3/fulltext NephJC discussion of Pathway2 http://www.nephjc.com/pathway The DIAMOND Trial. Much more ambitious than I described in the podcast. https://clinicaltrials.gov/ct2/show/NCT03888066 SPRINT https://www.nejm.org/doi/full/1...

Cast: Joel Topf Samira Farouk Jennie Lin Swapnil Hiremath and special guest, Perry Wilson A clinically applicable approach to continuous prediction of future acute kidney injury. https://www.ncbi.nlm.nih.gov/pubmed/?term=A+clinically+applicable+approach+to+continuous+prediction+of+future+acute+kidney+injury# Deep Mind National Health services scandal https://www.telegraph.co.uk/technology/2017/07/...

Cast: Joel Topf Jennie Lin Swapnil Hiremath Matt Sparks Show Notes: NephJC Coverage of MENTOR : http://www.nephjc.com/news/mentor MENTOR : https://www.nejm.org/doi/full/10.1056/NEJMoa1814427 KDIGO Membranous recommendations : https://kdigo.org/wp-content/uploads/2017/02/KDIGO-2012-GN-Guideline-English.pdf 2017 Kidney Week Abstract : https://www.asn-online.org/education/kidneyweek/2017/program-abst...

Cast: Joel Topf Jennie Lin Samira Farouk Swapnil Hiremath Show Notes: NephJC coverage of SONAR : http://www.nephjc.com/news/sonar SONAR in PubMed : https://www.ncbi.nlm.nih.gov/pubmed/30995972 Avosentan for overt diabetic nephropathy, the ASCEND trial : https://www.ncbi.nlm.nih.gov/pubmed/20167702 RADAR coverage at NephJC, May 2014 : http://www.nephjc.com/atrasentan RADAR in PubMed : https://www.n...

Joel Topf Jennie Lin Matt Sparks Swapnil Hiremath Show Notes: IgA Nephropathy Score Levi Strauss: https://www.biography.com/fashion-designer/levi-strauss Levey MDRD study: https://www.ncbi.nlm.nih.gov/pubmed/10075613 ADPKD Total Kidney Volume: https://www.nejm.org/doi/10.1056/NEJMoa054341 Halt PKD: https://www.nejm.org/doi/full/10.1056/nejmoa1402685 Tempo 3:4 Trial: https://www.nejm.org/doi/full/1...

Joel Topf Jennie Lin Matt Sparks Samira Farouk The strange story of Jennifer Strange. https://insiderexclusive.com/radios-deadly-stunts-the-jennifer-strange-story/ Water Poker https://www.thelocal.se/20120706/41878 Nintendo Game Consoles https://en.wikipedia.org/wiki/Nintendo_video_game_consoles 2019 Narins winner, Mitchel Rosner on MDMA induced hyponatremia https://www.ncbi.nlm.nih.gov/pubmed/186...

This week we discussed the CREDENCE trial published in the NEJM, on the effect of Canaglifozin on diabetic nephropathy. There was lots to discuss so it may be a long podcast. The article is available here . The NephJC summary can be read here , with links to the visual abstract, and the wrapup. Links from the show: Swapnil’s first post at AJKDblog on SGLT2i in 2014! SGLT-2 Inhibitors: Can They Pre...

This week we discussed the ASCEND trial published in Annals of Internal Medicine, on the comparative effectiveness of cognitive behavioural therapy and Sertraline in patients on dialysis with depression. The article is available here . The NephJC summary can be read here , with links to the visual abstract. Links from the show: In the background section, we mentioned the data from a recent JASN st...

This is the audio commentary of the NephJC Chats on March 19 and 20, 2019. This week we discussed the study published in JAMA Network Open, on the kidney outcomes in NSAID users from the US military. The article (open access) is available here . The NephJC summary can be read here , with links to the visual abstract. Links from the show: In the background section, we mentioned the data from the Ph...