NephJC Team

Freely Filtered, a NephJC Podcast

Health EN ↓ 94 episodes

Twice monthly (aspirational) recap of the NephJC journal club. NephJC reviews the most important manuscripts which are driving nephrology forward and improving our understanding of the kidney.

Author

NephJC Team

Category

Health

Podcast website

www.nephjc.com

Latest episode

Jun 30, 2026

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Episodes

Episode 70: Predicting Preeclampsia, the PRAECIS trial 26.05.2024

The Filtrate: Joel Topf Swapnil Hiremath AC Gomez Nayan Arora With Special Guest: Anuja Java , complement god and pre-eclampsia research ( Twitter ) Shannon M. Clark , MD, FACOG, an honest to god, true, maternal-fetal medicine specialist. ( Website | Instagram ) Editor Nayan Arora Show Notes CHIP Study from 2015 ( NEJM | NephMadness 2015 ) CHAP study from 2022 ( NEJM | NephJC ) NephMadness 2024 co...

Episode 69:DUPLEX Sparsentan, it’s no Acthar Gel 22.04.2024

The Filtrate: Joel Topf Swapnil Hiremath Priya Yenebere Nayan Arora With Special Guest: Brendon Neuen Super smart guy and clinical trialist Michelle Rheault Lead author of DUPLEX and friend of the pod Show Notes Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis NephJC Summary | PubMed | NEJM KDIGO FSGS Guidelines 2021 ( PDF ) Characterization of the Clinical Evidence Supporting Re...

Freely Filtered 68: Inpatient hypertension 16.03.2024

The Filtrate: Joel Topf Swapnil Hiremath Jordy Cohen AC Gomez With Special Guest: Tim Anderson @TimAndersonMD Editor: Priya Yenebere Show Notes Clinical Outcomes of Intensive Inpatient Blood Pressure Management in Hospitalized Older Adults NephJC Summary | PubMed | JAMA Internal Medicine The Jordy AC collab: An Interactive Ambulatory Nephrology Curriculum for Internal Medicine Interns: Design, Imp...

Freely Filtered 67: NephMadness and Animal House 07.03.2024

Animal House Region NephMadness description by Tiffany Truong Editorial by Kelly Hyndman @DrKeeksPhD They May Look Cute, But Are All Animals Sweet? The Filtrate: Joel Topf Swapnil Hiremath Sophia Ambruso Josh Waitzman With Special Guest: Kelly Hyndman Editor: Sophia Ambruso Show Notes Animal House 2018 with Mark Zeidel, MD ( AJKDblog ) Animal House 2021 with Kelly Hyndman ( AJKDBlog ) Animal House...

Freely Filtered 66: NephJC Summer Book Club 28.02.2024

How Medicine Works, and When It Doesn’t Amazon The Filtrate: Joel Topf Josh Waitzman Jennie Lin With Special Guest: Jade Teakell Perry Wilson Editor: Joel Topf Show Notes Understanding Medical Research: Your Facebook Friend is Wrong. Coursera Illusory truth effect ( Wikipedia ) Number needed to treat ( Wikipedia ) NNT at MedPage Today : NNT on NephJC Deaths of Despair: Suicide ( CDC 2001-2021 ) Dr...

Freely Filtered 065: BEST Fluids 10.02.2024

The Filtrate: Joel Topf Nayan Aurora Sophia Ambruso With Special Guest: Michael Collins Editor: Nayan Aurora Show Notes: Twitter is now X ( NYT ) Michael Collins ( the astronaut , not the real one) PlasmaLyte by Baxter NephJC BEST Fluids summary Early Goal Directed Therapy for Sepsis NEJM manuscript which changed practice patterns and welcomed in an era of massive fluid resuscitation. PLUS Trial N...

Freely Filtered 064: Freely Filtered with The Curbsiders Live at Kidney Week! 12.11.2023

The Filtrate: Joel Topf Swapnil Hiremath Sophia Ambruso AC Gomez Josh Waitzman Jennie Lin Nayan Arora The Curbsiders Matt F. Watto ( @DoctorWatto ) Paul Nelson Williams , America’s primary care physician ( @PaulNWilliamz ) With Special Guest: JD Foster ( @KidneyVet ) Sayed Tabatabai ( @TheRealDoctorT ) Nephrologist in Austin and the author of These Vital Signs Michelle Rheault ( @rheault_m ) Chief...

Freely Filtered 063: Late Breaking and High Impact Clinical Trial Simultaneous Release! 03.11.2023

The Filtrate: Joel Topf Swapnil Hiremath Sophia Ambruso AC Gomez With Special Guest: Amit Garg ( @AmitXGarg ) Nephrologist at Western University, London, and lead PI of the EnAKT LKD trial.  Susan Q. McKenzie ( LinkedIn ) Co-Founder & Chair, Transplant Ambassador Program. President of the Kidney Patient and Donor Alliance of Canada. Editor: Joel Topf Show Notes: Late Braking and High Impa...

Freely Filtered 062: Inaxaplin for APOL1 Kidney Disease 25.09.2023

The Filtrate: Joel Topf Jennie Lin Josh Waitzman With Special Guest: AC Gomez MedPeds nephrology fellow at Mass General/Brigham and Boston Children’s | Twitter Gentian Hall Assistant Professor of Medicine Duke Department of Medicine Editor: Sophia Ambruso Show Notes: APOL1 review by the OG Scientists APOL1 Nephropathy: From Genetics to Clinical Applications MYH9 and APOL1 connection: The populatio...

Freely Filtered 061: Bicarb in Transplant 24.09.2023

Bicarbonate did not slow the loss of GFR in this well done Swiss, single-blind study of transplant patients. The Filtrate: Joel Topf Nayan Arora Swapnil Hiremath Pirya Yenebere With Special Guest: Nav Tangri nephrologist and epidemiology at the University of Manitoba Editor: Nayan Arora Show Notes: Arsenal FC The London study that kicked it all off! de Brito-Ashurst, I., Varagunam, M., Raftery, M....

Freely Filtered 059: Furosemide v Torsemide 03.07.2023

The Filtrate: Joel Topf Nayan Arora Sophia Ambruso With Special Guest: Boback Ziaeian @boback Assistant Professor of Medicine David Geffen School of Medicine at UCLA. His Google Schoolar page is better than yours. And returning for her fourth time (why do we keep inviting her back?) Sadiya Khan @heartDocSadiya Assistant Professor of Medicine (Cardiology) and Preventative Medicine at Northwestern F...

Freely Filtered 060: HCTZ v Kidney Stones, The NOSTONE trial 25.06.2023

The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Nayan Arora Sophia Ambruso With Special Guest: Megan Prochaska Assistant professor of medicine at University of Chicago John Asplin Medical Director Consultant LithoLink ( Twitter ) Editor: Joel Topf Show Notes: The LithoLink website Stone Camp tweet Prevention of Repeated Episodes of Kidney Stones in Adults: A Clinical Practice Guideline From...

Freely Filtered 057: NephMadness 2023 TMA 11.03.2023

The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Sophia Ambruso With Special Guest: Anna Vinakova Associate Professor of Medicine at Virginia Commonwealth University. NephMadness Executive. Vanuja Java is a transplant nephrologist at Washington University in St. Louis, MO. Her research involves functional characterization of genetic variants in complement-mediated diseases. She co-chairs the...

Say "Hi" to the #NephMadness PodCrawl 01.03.2023

Welcome to the NephMadness PodCrawl The idea behind a podcrawl is for a variety of podcasts to coordinate on timing and topic to push a theme and get each other’s listeners to explore all of the podcasts. One of the first goals behind NephMadness was to build a community and in the early years of Twitter, NephMadness was central to the formation of #NephTwitter and defining the ethos that mak...

Freely Filtered 056: MyTEMP 07.02.2023

The Filtrate: Joel Topf Swapnil Hiremath Nayan Arora Sophia Ambruso With Special Guest: Amit Garg @AmitXGarg , Nephrologist at Western University, London, and lead PI of the MYTEMP trial.  Editor: Joel Topf Show Notes: MyTEMP in pubmed: Personalised cooler dialysate for patients receiving maintenance haemodialysis (MyTEMP): a pragmatic, cluster-randomised trial MyTEMP Summary on NephJC  ...

Freely Filtered 055: STOP ACE! 29.01.2023

The Filtrate: Joel Topf Swapnil Hiremath Jordy Cohen With Special Guest: Laurie Tomlinson . @Roxytonin Nephrologist at University Hospitals Sussex and research hero of Jordy. Editor: Priya Yenebere Show Notes: STOP-ACE in pubmed: Renin-Angiotensin System Inhibition in Advanced Chronic Kidney Disease STOP-ACE Summary in NephJC Prior data showing preservation of renal function by stopping ACEi: The...

Freely Filtered 054: EMPA Kidney! 25.12.2022

The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Sophia Ambruso Priya Yenebere With Special Guest: Brendon Neuen , Secretariat of the SGLT2 Trialists Consortium and cool guy on Twitter . Editor: Sophia Ambruso Show Notes: Joel’s Conflict of Interest Statement. Sophia is also conflicted with Astra Zeneca and Brendon with everybody in the SGLT2i space. Joel starts off with a history of SGLT2i...

Freely Filtered 053: The Kidney Week Draft 11.12.2022

The Filtrate: Joel Topf Swapnil Hiremath Nayan Arora Sophia Ambruso Editor: Nayan Arora Show Notes: Joel’s Conflict of Interest Statement The Draft Board EMPA-Kidney is “off the board” Lunch Symposium on Current and Future Approaches to the Diagnostic Assessment and Management of AKI in Patients with Cirrhosis provided by an educational grant from Mallinckrodt Pharmaceuticals The CONFIRM Trial Ter...

Freely Filtered 052: Acetazolamide for Acute Decompensated Heart Failure (ADVOR) 26.11.2022

The Filtrate: Joel Topf Jordy Cohen Nayan Arora Sophia Ambruso Special Guests: Boback Ziaeian @boback Assistant Professor of Medicine David Geffen School of Medicine at UCLA returns for his second episode ( SODIUM-HF ). His Google Schoolar page is better than yours. David Ellison @dhekidney is professor of medicine at Oregon Health Science University and head of the Oregon Clinical & Translati...

Freely Filtered 051: Pip Tazo and Vanco: Nephrotoxin or Not so toxic 17.10.2022

The Filtrate: Joel Topf Swapnil Hiremath Nayan Arora Priya Yenebere Special Guests: Todd Miano, PharmD, PhD @Miano81 Assistant Professor of Epidemiology, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine. Show Notes: Early Pip/Tazo article showing nephrotoxicity . Covered by NephJC Linazolid vs Vanco RCT showing excess AKI with Vanco. Yes Vance is a lot less to...

Freely Filtered 050: CLASSIC Trial 08.10.2022

The Filtrate: Joel Topf Swapnil Hiremath Jennie Lin Special Guests: Priya Yenebere @PriRenalAKI Transplant nephrologist at Indiana University School of Medicine. She is a current NSMC Intern. J Pedro Teixeira @NephCrit_NM ICU Nephrologist at the University of New Mexico. Editor: Priya Yenebere Show Notes: Critical Care Nephrology Critical Care Nephrology: Core Curriculum 2020 by Benjamin R Griffin...

Freely Filtered 049: Getting Salty with SODIUM-HF 13.09.2022

The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Sophia Ambruso Special Guests: Boback Ziaeian @boback Assistant Professor of Medicine David Geffen School of Medicine at UCLA. His Google Schoolar page is better than yours. And returning for her third time (why sdo we keep inviting her back?) Sadiya Khan @heartDocSadiya Assistant Professor of Medicine (Cardiology) and Preventative Medicine at...

Freely Filtered 048: Putting TESTING to the Test 01.08.2022

The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Jordy Cohen Special Guest: Sean Barbour . Clinical Associate Professor, Division of Nephrology, University of British Columbia Chair, BC Glomerulonephritis Committee and Network, BC Renal Editor: Joel Topf Show Notes: NephJC Summary of TESTING: Re-TESTING Steroids for IgA Nephropathy (have you ever noticed how good the titles for the NephJC su...

Freely Filtered 047: CHAP, time to treat hypertension in pregnancy 29.06.2022

The Filtrate: Joel Topf Nayan Arora Sophia Ambruso Swapnil Hiremath Josh Waitzman Special Guest: Natalie Bello Director of Hypertension Research at Cedars Sinai Editor: Nayan Arora Show Notes: NephJC summary of CHAP CHiPS TV show CHIPS study: Less-Tight versus Tight Control of Hypertension in Pregnancy Prevention, Diagnosis, and Management of Hypertensive Disorders of Pregnancy: a Comparison of In...

Freely Filtered 046: The ISPD Peritonitis Guideline Draft 14.05.2022

The Filtrate: Joel Topf Nayan Arora Sophia Ambruso Swapnil Hiremath Special Guest: Jade Teakall Jeff Perl, Great Twitter handle, PD_Perls Editor: Joel Topf Show Notes: ISPD 2022 Peritonitis Guidelines NephJC Discussion Dimitrios Oreopoulos obituary in JASN . Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis The draft board: Google Doc The PROMPT Study...

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