Healthspan

96. Empagliflozin in Patients with Chronic Kidney Disease 19.04.2025 13:40 ↓

https://www.nejm.org/doi/full/10.1056/NEJMoa2204233

95. Tirzepatide Once Weekly for the Treatment of Obesity 30.11.2024 14:15 ↓

SURMOUNT 1 Trial. The aim of this trial was to investigate the safety and efficacy of Tirzepatide, a novel GLP + GIP in people with obesity. We discuss the trial in this episode.

94. Effects of Semaglutide on CKD in Patients with Type 2 Diabetes 07.10.2024 11:00 ↓

@ michaelsalzle Patients with diabetes and chronic disease are at high risk for kidney failure, cardiovascular events, and death. The FLOW trial looked at the safety and efficacy of semaglutide in patients with chronic disease and type 2 diabetes.

93. How Not To Age, by Dr. Michael Greger - Part 6. Preservation 2 28.09.2024 21:06 ↓

@michaelsalzle Preservation of your immune system, mind, and muscle

92. How Not To Age, by Dr. Michael Greger - Part 5. Preservation 21.09.2024 26:58 ↓

@michaelsalzle In this episode, we learn how to preserve our bones, bowel, circulation, hair, hearing, and hormones.

91. How Not To Age, by Dr. Michael Greger - Part 4. Centenarian/Mediterranean diets, and Lifestyle 04.07.2024 25:08 ↓

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90. How Not To Age, by Dr. Michael Greger - Part 3. mTOR, Sirtuins, Telomeres, and Oxidation 19.05.2024 19:49 ↓

@michaelsalzle

89. How Not To Age, by Dr. Michael Greger - Part 2. Glycation, IGF, and Inflammation 08.05.2024 22:32 ↓

@michaelsalzle

88. How Not To Age, by Dr. Michael Greger - Part 1. AMPK, Senescence, Autophagy, and Epigenetics 17.03.2024 27:56 ↓

@michaelsalzle. In this episode, we discussed pathways of aging. We discuss the importance of genes, AMPK, autophagy, metformin, foods that boost AMPK, autophagy, foods that boost autophagy, spermidine,epigenetics, and cellular senescence

87. Outlive, by Dr. Peter Attia - Part 11. Emotional Health 14.01.2024 14:47 ↓

@michaelsalzle

86. Outlive, by Dr. Peter Attia - Part 10. Nutrition 3.0 (part 2) and Sleep 22.12.2023 16:14 ↓

@michaelsalzle

85. Outlive, by Dr. Peter Attia - Part 9. Nutrition 3.0 (part 1) 15.12.2023 26:11 ↓

@michaelsalzle. In this episode we discuss nutrition 3.0. Epidemiology, clinical trials. The Mediterranean diet, the University of Wisconsin CR trial vs the NIH CR trial, carbohydrates, and protein.

84. Outlive, by Dr. Peter Attia - Part 8. VO2 max, Strength, and Stability for longevity 26.11.2023 12:49 ↓

@michaelsalzle

83. Outlive, by Dr. Peter Attia - Part 7. Exercise, the Centenarian Decathlon, and Zone 2 training 17.09.2023 17:37 ↓

IG: @michaelsalzle. In this episode, we go into the broad topic of exercise. Exercise is considered the most powerful longevity drug. We review studies that underscore the importance of exercise. We also discuss the centenarian decathlon, and take a deep dive into zone 2 training.

82. Outlive, by Dr. Peter Attia - Part 6. Chasing memory. Understanding Alzheimer’s Disease 20.08.2023 25:00 ↓

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81. Outlive, by Dr. Peter Attia - Part 5. Cancer, cancer metabolism, immunotherapy, and prevention 30.07.2023 26:18 ↓

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80. Outlive, by Dr. Peter Attia - Part 4. Metabolic Syndrome, ASCVD, and Lipidology 15.07.2023 22:37 ↓

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79. Outlive, by Dr. Peter Attia - Part 3. Centenarians, Rapamycin, and Calorie Restriction 21.06.2023 19:54 ↓

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78. Outlive, by Dr Peter Attia - Part 2. Medicine 3.0. Objective, Strategy, and Tactics 09.06.2023 20:55 ↓

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77. Outlive, by Dr. Peter Attia - Part 1. The four horseman, fast death, slow death, and longevity 20.05.2023 16:26 ↓

@michaelsalzle. The Long Game

76. The History of Rapamycin and mTOR. David Sabatini’s journey to discovering mTOR. 06.05.2023 22:11 ↓

https://www.pnas.org/doi/10.1073/pnas.1716173114 @michaelsalzle

75. Young Forever, by Mark Hyman - Part 3. Eating for Longevity, Exercise, Hormesis, and Purpose 22.04.2023 22:06 ↓

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74. Young Forever, by Mark Hyman - Part 2. The hallmarks of aging, and finding balance 09.04.2023 25:51 ↓

@michaelsalzle

72. Metformin in Aging and Aging - Related Diseases, by Chen et al - Part 2 11.03.2023 23:48 ↓

@michaelsalzle Metformin and it’s effect on the hallmarks of aging https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965502/#abstract-1title

71. Metformin in Aging and Aging - Related Diseases, by Chen et al - Part 1 10.02.2023 21:54 ↓

@michaelsalzle. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965502/#abstract-1title