Base by Base - Music

This release contains only the music track from Base by Base Episode 411. Song title: Spots in the Dark Original Base by Base episode: 411: EKV cells and the Human Prion Assay: a scalable platform for sCJD infectivity Article metadata: Article title: A scalable, dividing cell model for the robust propagation and quantification of human sporadic Creutzfeldt–Jakob disease prions Journal: PNAS DOI: 1...

This release contains only the music track from Base by Base Episode 410. Song title: More Than a Number Original Base by Base episode: 410: Nucleotide diversity is a poor predictor of short-term adaptive potential Article metadata: Article title: Nucleotide diversity is a poor predictor of short-term adaptive potential Journal: PNAS DOI: 10.1073/pnas.2536181123 Reference: Abson KL, Zijmers L, Mit...

This release contains only the music track from Base by Base Episode 409. Song title: Modular Fire in the Sugarlight Original Base by Base episode: 409: A systems-level atlas of carbon-response transcriptional states in Escherichia coli Article metadata: Article title: A systems-level atlas of carbon-response transcriptional states in Escherichia coli Journal: PNAS DOI: 10.1073/pnas.2531884123 Ref...

This release contains only the music track from Base by Base Episode 408. Song title: Fusion Switch (Tau Let Go) Original Base by Base episode: 408: Tau, mitochondria, and the fusion switch Article metadata: Article title: Tau protein as a regulator of mitochondrial function and dynamics Journal: Proceedings of the National Academy of Sciences (PNAS) DOI: 10.1073/pnas.2521642123 Reference: Tsakiri...

This release contains only the music track from Base by Base Episode 407. Song title: Lock the Metals Away Original Base by Base episode: 407: SLC11A2 withholds metals from Salmonella in the gut epithelium Article metadata: Article title: SLC11A2 withholds divalent metals from Salmonella in the gut epithelium Journal: Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.2532675123 Ref...

This release contains only the music track from Base by Base Episode 406. Song title: Cold Side of the Gut Original Base by Base episode: 406: Temperature & Age Shape Gut Susceptibility to HCoV-229E Article metadata: Article title: Temperature and developmental stage govern intestinal susceptibility to human coronavirus 229E Journal: Proceedings of the National Academy of Sciences (PNAS) DOI:...

This release contains only the music track from Base by Base Episode 405. Song title: Symmetry in the Sparks Original Base by Base episode: 405: PRDM9 and the Hotspot Trade-off Article metadata: Article title: On the origin of PRDM9-guided recombination hotspots Journal: Proceedings of the National Academy of Sciences (PNAS) DOI: 10.1073/pnas.2535682123 Reference: Úbeda F, Bürger R, Fyon F. On the...

This release contains only the music track from Base by Base Episode 404. Song title: DNA on the Outside Original Base by Base episode: 404: RUNA Reveals Surface DNA on Exosomes Article metadata: Article title: A nucleic acid labeling chemistry reveals surface DNA on exosomes Journal: Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.2532281123 Reference: Bošković F, Dutta Gupta P,...

This release contains only the music track from Base by Base Episode 404. Song title: Scars That Tell the Truth Original Base by Base episode: 404: HRD-GIS refines BRCA1/2 variant classification in ovarian cancer Article metadata: Article title: Homologous recombination deficiency-driven genomic instability in ovarian cancer as an indicator of BRCA1 and BRCA2 variant pathogenicity Journal: The Ame...

This release contains only the music track from Base by Base Episode 403. Song title: Scars That Tell the Truth Original Base by Base episode: 403: HRD-GIS Evidence for BRCA1/2 Variant Classification Article metadata: Article title: Homologous recombination deficiency-driven genomic instability in ovarian cancer as an indicator of BRCA1 and BRCA2 variant pathogenicity Journal: The American Journal...

This release contains only the music track from Base by Base Episode 402. Song title: Outliers in the Light Original Base by Base episode: 402: When Polygenic Scores Miss: Rare Variants in Misaligned Individuals Article metadata: Article title: Individuals who deviate from polygenic expectation are enriched for damaging variants in genes linked to rare disease Journal: The American Journal of Huma...

This release contains only the music track from Base by Base Episode 401. Song title: Two Ends of the Same Thread Original Base by Base episode: 401: LDB1 variants split neurodevelopmental outcomes by location and mechanism Article metadata: Article title: De novo variants in LDB1 are linked to distinct neurodevelopmental phenotypes determined by variant location and differing pathomechanisms Jour...

This release contains only the music track from Base by Base Episode 401. Song title: Two Ends of the Same Thread Original Base by Base episode: 401: LDB1 variants split neurodevelopmental outcomes by location and mechanism Article metadata: Article title: De novo variants in LDB1 are linked to distinct neurodevelopmental phenotypes determined by variant location and differing pathomechanisms Jour...

This release contains only the music track from Base by Base Episode 400. Song title: Tenfold Between Us Original Base by Base episode: 400: Complete chromosome 21 centromere sequencing and Down syndrome Article metadata: Article title: Complete chromosome 21 centromere sequencing of families with Down syndrome Journal: The American Journal of Human Genetics DOI: 10.1016/j.ajhg.2026.05.010 Referen...

This release contains only the music track from Base by Base Episode 399. Song title: Spiral in the Signal Original Base by Base episode: 399: Ménière disease: inner ear development and retinoic acid pathways Article metadata: Article title: Genome-wide analysis implicates inner ear development in Ménière disease Journal: The American Journal of Human Genetics DOI: 10.1016/j.ajhg.2026.05.011 Refer...

This release contains only the music track from Base by Base Episode 398. Song title: Not Just the Slope Original Base by Base episode: 398: Modeling JAK2V617F Clonal Expansion in the General Population Article metadata: Article title: Mathematical modeling of JAK2V617F clonal expansion in a general population cohort Journal: Proceedings of the National Academy of Sciences (PNAS) DOI: 10.1073/pnas...

This release contains only the music track from Base by Base Episode 397. Song title: Hazy Tree, True Time Original Base by Base episode: 397: SciPhy: Bayesian phylogenetics for sequential genetic lineage tracing Article metadata: Article title: SciPhy: A Bayesian phylogenetic framework using sequential genetic lineage tracing data Journal: Nature Communications DOI: 10.1038/s41467-026-73377-6 Ref...

This release contains only the music track from Base by Base Episode 396. Song title: Helix in the Dark Original Base by Base episode: 396: Physical homology recognition between DNA duplexes Article metadata: Article title: Direct evidence and quantification of homologous recognition between DNA duplexes Journal: Proceedings of the National Academy of Sciences (PNAS) DOI: 10.1073/pnas.2530949123 Re...

This release contains only the music track from Base by Base Episode 395. Song title: Context Writes the Curve Original Base by Base episode: 395: Extended sequence context shapes mutational bias in Escherichia coli Article metadata: Article title: Extended sequence context shapes mutational bias in Escherichia coli Journal: PNAS DOI: 10.1073/pnas.2601345123 Reference: Green R., Jago M.J., Knight...

This release contains only the music track from Base by Base Episode 394. Song title: Panels in the Noise Original Base by Base episode: 394: Benchmarking LLMs for cfRNA biomarker discovery Article metadata: Article title: Benchmarking large language models for cell-free RNA diagnostic biomarker discovery Journal: Nature Communications DOI: 10.1038/s41467-026-74077-x Reference: Gaudio HA, Bliss A,...

This release contains only the music track from Base by Base Episode 393. Song title: Hidden in the Bands Original Base by Base episode: 393: Hidden Resistance: tNGS Reveals Rifampicin and Bedaquiline Resistance in Eswatini Article metadata: Article title: Targeted next-generation sequencing implementation in Eswatini identifies rifampicin and bedaquiline resistance undetected by routine diagnosti...

This release contains only the music track from Base by Base Episode 392. Song title: Intervals in the Dark Original Base by Base episode: 392: GWAS of Cocaine Self-Administration in Heterogeneous Stock Rats Article metadata: Article title: Genome-wide association study of cocaine self-administration behavior in Heterogeneous Stock rats Journal: Nature Communications DOI: https://doi.org/10.1038/s...

This release contains only the music track from Base by Base Episode 391. Song title: Fight With Grace Original Base by Base episode: 391: The Kaufmann Protocol — Why We Age and How to Stop It Article metadata: Article title: Why We Age and How to Stop It: The Kaufmann Protocol Journal: The Kaufmann Anti-Aging Institute Reference: Kaufmann, S. Why We Age and How to Stop It — The Kaufmann Protocol....

This release contains only the music track from Base by Base Episode 390. Song title: Mutual Destruction Original Base by Base episode: 390: Daunorubicin, Mutual Destruction, and Layered Antiphage Defense Article metadata: Article title: DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity Journal: PNAS DOI: https://doi.o...

This release contains only the music track from Base by Base Episode 389. Song title: Crotonylation, Hold the Line Original Base by Base episode: 389: Crotonylation impedes c-Myc oncogenic activity Article metadata: Article title: Crotonylation impedes c-Myc oncogenic activity Journal: PNAS DOI: 10.1073/pnas.2530020123 Reference: https://doi.org/10.1073/pnas.2530020123 Lyrics: Verse 1 Under white...