Base by Base - Music

This release contains only the music track from Base by Base Episode 462. Song title: Along the Vessels Original Base by Base episode: 462: A vessel gene tied to AMD dims low-light vision in mice Article metadata: Article title: Genetic evidence and cross-species functional characterization implicate CNN2 in age-related macular degeneration susceptibility Journal: Proceedings of the National Acade...

This release contains only the music track from Base by Base Episode 461. Song title: Dimmer Underneath Original Base by Base episode: 461: Adult Ank3 loss quiets neurons and lowers a myelin protein Article metadata: Article title: Ank3 loss in adult forebrain excitatory neurons disrupts behavior, neuronal activity, membrane proteome, and myelination Journal: Proceedings of the National Academy of...

This release contains only the music track from Base by Base Episode 460. Song title: Same Dial Original Base by Base episode: 460: The lupus variant that also sharpens antiviral defense Article metadata: Article title: A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-α, enhancing antiviral defense and exacerbating autoimmunity Journal: The American Journal of Huma...

This release contains only the music track from Base by Base Episode 459. Song title: Five Hundred Names Original Base by Base episode: 459: Cerebral palsy genetics: 515 candidate genes, evidence for 89 Article metadata: Article title: A phenotypic paradigm for cerebral palsy genetics Journal: The American Journal of Human Genetics DOI: 10.1016/j.ajhg.2026.08.007 Reference: Arterbery, A.S., Gargan...

This release contains only the music track from Base by Base Episode 458. Song title: Half Means Home Original Base by Base episode: 458: Somatic or inherited? Reading TP53 risk from shared DNA Article metadata: Article title: Shared inheritance reveals landscape of somatic and germline cancer risk in TP53 Journal: The American Journal of Human Genetics DOI: 10.1016/j.ajhg.2026.07.011 Reference: M...

This release contains only the music track from Base by Base Episode 457. Song title: One Less, One More Original Base by Base episode: 457: A deletion that raises Alzheimer risk, a duplication that lowers it Article metadata: Article title: Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk Journal: The American Journal of Human Ge...

This release contains only the music track from Base by Base Episode 456. Song title: Where the Light Is Original Base by Base episode: 456: Beyond exons: where heritability hides as traits get more polygenic Article metadata: Article title: Beyond exons: Linking noncoding heritability and polygenicity across complex human traits and disorders Journal: The American Journal of Human Genetics DOI: 1...

This release contains only the music track from Base by Base Episode 455. Song title: All Normal Original Base by Base episode: 455: Agentic genomics: the bottleneck moves from code to judgment Article metadata: Article title: Agentic genomics: From pipeline automation to autonomous validation Journal: Cell Genomics DOI: 10.1016/j.xgen.2026.101305 Reference: Corpas M, Guio H, Fatumo S. Agentic gen...

This release contains only the music track from Base by Base Episode 454. Song title: Remédio de Outra Guerra Original Base by Base episode: 454: Efavirenz retarda a doença priônica mexendo no colesterol do cérebro [PT] Article metadata: Article title: Treatment with efavirenz extends survival in a Creutzfeldt-Jakob disease model by regulating brain cholesterol metabolism Journal: JCI Insight DOI:...

This release contains only the music track from Base by Base Episode 453. Song title: Turn the Tide in My Brain Original Base by Base episode: 453: Efavirenz slows sCJD progression by reshaping brain cholesterol Article metadata: Article title: Treatment with efavirenz extends survival in a Creutzfeldt-Jakob disease model by regulating brain cholesterol metabolism Journal: JCI Insight DOI: 10.1172...

This release contains only the music track from Base by Base Episode 452. Song title: Quem Ainda Faz Ninho Original Base by Base episode: 452: Reduzir a PrP funciona em todas as linhagens [PT] Article metadata: Article title: Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints Journal: Nucleic Acids Research DOI: 10.1093/nar/gkaa616 Reference: M...

This release contains only the music track from Base by Base Episode 451. Song title: Lower the Signal Original Base by Base episode: 451: Prion protein lowering is disease-modifying across stages and strains Article metadata: Article title: Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints Journal: Nucleic Acids Research DOI: 10.1093/nar/gkaa...

This release contains only the music track from Base by Base Episode 450. Song title: Ainda Tem Chão Original Base by Base episode: 450: PrP-Lowering ASOs Extend Survival in Prion-Infected Mice Article metadata: Article title: Antisense oligonucleotides extend survival of prion-infected mice Journal: JCI Insight DOI: 10.1172/jci.insight.131175 Reference: Raymond GJ, Zhao HT, Race B, et al. Antisen...

This release contains only the music track from Base by Base Episode 449. Song title: Corta a Fita, Salva a Luz Original Base by Base episode: 449: Divalent siRNA for prion disease Article metadata: Article title: Divalent siRNA for prion disease Journal: Nucleic Acids Research DOI: 10.1093/nar/gkag287 Reference: Gentile JE, Corridon TL, Serack FE, et al. Divalent siRNA for prion disease. Nucleic...

This release contains only the music track from Base by Base Episode 448. Song title: Silence the Spark Original Base by Base episode: 448: PrP‑lowering ASOs prolong survival in prion‑infected mice Article metadata: Article title: Antisense oligonucleotides extend survival of prion‑infected mice Journal: JCI Insight DOI: 10.1172/jci.insight.131175 Reference: Raymond GJ, Tran Zhao H, Race B, Raymon...

This release contains only the music track from Base by Base Episode 447. Song title: Cut the Thread, Save the Light Original Base by Base episode: 447: Divalent siRNA for prion disease Article metadata: Article title: Divalent siRNA for prion disease Journal: Nucleic Acids Research DOI: 10.1093/nar/gkag287 Reference: Gentile JE, Corridon TL, Serack FE, Echeverria D, Kennedy ZC, et al. Divalent si...

This release contains only the music track from Base by Base Episode 446. Song title: Signals in the Quiet Antenna Original Base by Base episode: 446: Cilia, Synuclein, and Survival: G51D Mice Reveal a Shared Parkinson’s Pathway Article metadata: Article title: Selective loss of primary cilia and neurotrophic signaling in G51D α- synuclein mice highlights a common pathway to Parkinson’s disease Jo...

This release contains only the music track from Base by Base Episode 445. Song title: Dimers in the Dawn Original Base by Base episode: 445: Why Thymine Survived the UV: Photodamage Pathways Explained Article metadata: Article title: UV photodamage pathways and the evolutionary selection of thymine over uracil in early genetic systems Journal: PNAS DOI: 10.1073/pnas.2615278123 Reference: Khosh Aba...

This release contains only the music track from Base by Base Episode 444. Song title: Curves in the Watch Original Base by Base episode: 444: Many-eyes or Sentinels? How Cost Curvature Shapes Collective Vigilance Article metadata: Article title: Many-eyes and sentinels in selfish and cooperative groups Journal: PNAS DOI: 10.1073/pnas.2536017123 Reference: Pilgrim C, Bate AM, Sigalou A, Aellen M, Mo...

This release contains only the music track from Base by Base Episode 444. Song title: Curves in the Watch Original Base by Base episode: 444: Many-eyes or Sentinels? How Cost Curvature Shapes Collective Vigilance Article metadata: Article title: Many-eyes and sentinels in selfish and cooperative groups Journal: PNAS DOI: 10.1073/pnas.2536017123 Reference: Pilgrim C, Bate AM, Sigalou A, Aellen M, Mo...

This release contains only the music track from Base by Base Episode 443. Song title: Skip the Broken Beat Original Base by Base episode: 443: 5D‑ASO boosts exon 51 skipping and restores dystrophin in DMD models Article metadata: Article title: An antisense method for efficient exon skipping and its application to Duchenne muscular dystrophy Journal: PNAS DOI: 10.1073/pnas.2606494123 Reference: Fe...

This release contains only the music track from Base by Base Episode 442. Song title: Pump the Light Back In Original Base by Base episode: 442: When pumps go missing: Ca2+ control of PMCA2 in Tmc1 deafness mutants Article metadata: Article title: Ca2+ regulation of PMCA2 calcium pump expression in hair cells of Tmc1 deafness mutants Journal: Proceedings of the National Academy of Sciences (PNAS)...

This release contains only the music track from Base by Base Episode 441. Song title: Voltage in the Margins Original Base by Base episode: 441: Evolutionary mapping of Cav1.3 functional sites Article metadata: Article title: Identification of novel functional sites in the Cav1.3 calcium channel α1-subunit using evolutionary modeling Journal: PNAS DOI: 10.1073/pnas.2602636123 Reference: Tang X, He...

This release contains only the music track from Base by Base Episode 440. Song title: Scars on the Signal Original Base by Base episode: 440: DENV-4: Suppressing DNA Repair and Causing Genome Damage Article metadata: Article title: DENV-4 infection suppresses transcription of DNA repair genes Journal: PNAS DOI: 10.1073/pnas.2536909123 Reference: Lamkina EN, Reich J, Victora JA, et al. DENV-4 infec...

This release contains only the music track from Base by Base Episode 440. Song title: Scars on the Signal Original Base by Base episode: 440: DENV-4: Suppressing DNA Repair and Causing Genome Damage Article metadata: Article title: DENV-4 infection suppresses transcription of DNA repair genes Journal: PNAS DOI: 10.1073/pnas.2536909123 Reference: Lamkina EN, Reich J, Victora JA, et al. DENV-4 infec...