Science TLDR

A genetic common factor underlying self-reported math ability and highest math class taken 11.10.2025 16:07 ↓

https://doi.org/10.1038/s41380-025-03237-0

Profiling Hinge Plasticity in Intact Monoclonal Antibodies for Antigen Recognition 15.09.2025 13:57 ↓

https://doi.org/10.1021/acs.biochem.5c00274

The impact of CD3 affinity-attenuation on T cell engaging bispecific antibodies: is it really that simple? 12.09.2025 17:02 ↓

DOI: 10.1080/17460441.2025.2522088

Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy 29.08.2025 19:23 ↓

https://doi.org/10.1016/j.cell.2025.07.046

Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy 26.08.2025 20:18 ↓

https://doi.org/10.1038/s41586-025-09370-8

AlphaEarth Foundations: An embedding field model for accurate and efficient global mapping from sparse label data 06.08.2025 18:47 ↓

arXiv:2507.22291v1

Single-Chain Fab Chain-Exchange (scFab-PACE) converts targeted prodrugs into functional T cell engagers on tumor cells 05.08.2025 16:30 ↓

https://doi.org/10.1016/j.jbc.2025.110490

Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement 04.08.2025 12:05 ↓

https://doi.org/10.1016/j.celrep.2025.115965

Navigating protein landscapes with a machine-learned transferable coarse-grained model 30.07.2025 15:34 ↓

https://doi.org/10.1038/s41557-025-01874-0

Sliding Window Interaction Grammar (SWING): a generalized interaction language model for peptide and protein interactions 30.07.2025 16:44 ↓

https://doi.org/10.1038/s41592-025-02723-1

Predicting human decisions with behavioural theories and machine learning 29.07.2025 18:03 ↓

https://doi.org/10.1038/s41562-025-02267-6

Tuning antibody stability and function by rational designs of framework mutations 27.07.2025 14:28 ↓

https://doi.org/10.1080/19420862.2025.2532117

Lying increases trust in science 26.07.2025 13:08 ↓

https://doi.org/10.1007/s11186-025-09635-1

Soil and cherry bacterial communities predict flavor on coffee farms 20.06.2025 6:16 ↓

https://doi.org/10.1038/s41598-025-03665-6

What Is It Like to Be a Bat? 12.06.2025 10:43 ↓

https://www.jstor.org/stable/2183914

3 Papers on Antibody Tumor Penetration and Clearance 07.06.2025 15:19 ↓

Mixing it up a little with an episode covering 3 papers on the same topic. Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearancedoi:10.1016/j.addr.2008.04.012. A highly stable human single-domain antibody-drug conjugate exhibits superior penetration and treatment of solid tumorshttps://doi.org/10.1016/j.ymthe.2022.04.013. Influence of molecular size on tissue dis...

Why people follow rules 03.06.2025 6:50 ↓

https://doi.org/10.1038/s41562-025-02196-4

Cross-tissue multicellular coordination and its rewiring in cancer 31.05.2025 18:11 ↓

doi: 10.1038/s41586-025-09053-4

Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity 27.05.2025 13:21 ↓

https://doi.org/10.1038/s41586-025-08997-x

Deep-learning-based single-domain and multidomain protein structure prediction with D-I-TASSER 26.05.2025 11:24 ↓

https://doi.org/10.1038/s41587-025-02654-4

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease 20.05.2025 12:51 ↓

DOI: 10.1056/NEJMoa2504747

Adversarial testing of global neuronal workspace and integrated information theories of consciousness 02.05.2025 9:34 ↓

https://www.nature.com/articles/s41586-025-08888-1

Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease 14.04.2025 13:17 ↓

https://doi.org/10.1038/s41586-025-08852-z

A natural experiment on the effect of herpes zoster vaccination on dementia 07.04.2025 11:50 ↓

DOI: 10.1038/s41586-025-08800-x

The end of the genetic paradigm of cancer 02.04.2025 25:31 ↓

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003052