Ed Delesky, MD and Nicole Aruffo, RN
Your Checkup: Patient Education Health Podcast
Ever leave the doctor’s office more confused than when you walked in? Your Checkup: Health Conversations for Motivated Patients is your health ally in a world full of fast appointments and even faster Google searches. Each week, a board certified family medicine physician and a pediatric nurse sit down to answer the questions your doctor didn’t have time to. From understanding diabetes and depression to navigating obesity, high blood pressure, and everyday wellness—we make complex health topics simple, human, and actually useful. Whether you’re managing a condition, supporting a loved one, or...
Author
Ed Delesky, MD and Nicole Aruffo, RN
Category
Podcast website
Latest episode
Jul 6, 2026
Where to listen?
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Episodes
120: Can Lifting Weights Help Prevent a Heart Attack? 06.07.2026 20:52
Cardio has been the default prescription for heart health for decades, but a growing body of evidence suggests we’ve been overlooking a major protective tool: strength training. We dig into a large, long-running research dataset that followed more than 117,000 women for nearly 15 years and found a powerful link between resistance training and lower heart attack risk. The number that stops people i...
119: Can Medicare Finally Cover Weight Loss Meds? Understanding the New GLP-1 Bridge Program 29.06.2026 29:18
We break down Medicare’s brand-new GLP-1 Bridge Program and explain why headlines are both true and incomplete. We lay out the real eligibility rules, the $50 copay promise, and the smarter questions to ask so you and your clinician can find the right coverage pathway. • why Medicare historically excludes weight loss medications and what changed with modern obesity medicine • what the GLP-1 Brid...
118: When Should You Consider an Antidepressant? 22.06.2026 28:06
The hardest part about antidepressants is often not the pill, it is the question you ask yourself before you ever bring it up: “Is this serious enough?” We think that question keeps too many people stuck. We are Ed Delesky (family medicine doctor) and Nicole Aruffo (nurse), and we walk through a clearer test: is depression or anxiety affecting your ability to live your life the way you want to liv...
117: Migraine Explained: Triggers, Treatment, and When to Worry for Patients 15.06.2026 52:50
We break down migraines as a neurologic condition with a real brain-based chain reaction, not a character flaw or a one-off “bad headache.” We share practical prevention habits, how to track triggers, and how acute and preventive migraine medications fit together so you can walk into your next visit prepared. • what makes a migraine different from other headache types • common and less common mi...
116: Can Weight Loss Medications (GLP1s) Reduce Breast Cancer Risk? 08.06.2026 26:01
A headline like “weight loss drugs may reduce breast cancer risk” grabs attention fast, but the real story lives in the fine print. We take you through a new Penn Medicine study that observed lower breast cancer rates among women with overweight or obesity who used GLP-1 medications, then we translate what that finding actually means in plain language. Observational data can reveal a signal worth...
115: Are Food Preservatives Raising Your Blood Pressure? A New Study Explained 01.06.2026 27:03
That scary nutrition headline about preservatives and high blood pressure is everywhere right now and it’s easy to jump straight from “linked” to “proven.” We slow it down and do what we’d do in an exam room: look at what the study actually says, what it doesn’t say, and how to translate it into real-life choices that protect your heart without turning grocery shopping into a panic spiral. We talk...
114: COPD Explained Clearly for Patients 25.05.2026 20:13
Breathing out shouldn’t feel like pushing air through a straw, but for millions of people that’s the daily reality of COPD. We sit down and translate chronic obstructive pulmonary disease into plain English, starting with what the name really means and why the main problem is often getting air out, not just getting air in. If you’ve ever heard someone say they “can’t catch their breath,” we give y...
113: Health Trends Everywhere Right Now: Hype vs Reality 18.05.2026 41:53
Cortisol is getting blamed for basically everything online, and we get why it’s tempting: it gives a neat explanation for feeling tired, stressed, bloated, or “off.” But as a family medicine doctor and a nurse, we want to bring the conversation back to what cortisol actually does, what real testing looks like, and why most people don’t need to treat normal life stress like a hormonal crisis. From...
112: Hantavirus Explained: Why Experts Are Watching This Rare Virus 11.05.2026 24:23
“Rare, deadly virus” is a phrase that can hijack your nervous system, especially after the last few years. We slow the whole story down and walk through what hantavirus is, why it’s trending again, and how to tell the difference between a serious public health investigation and a true pandemic threat. We start with the headline that pulled hantavirus back into the spotlight: an unusual outbreak ti...
111: What To Expect When You Begin a GLP-1 04.05.2026 32:04
GLP-1 medications can feel like a Rorschach test online: one person calls Ozempic or Wegovy a miracle, another calls it miserable, and almost nobody explains what the “normal middle” looks like. We wanted to fix that with a practical walkthrough of what tends to happen after you start a GLP-1 receptor agonist, especially in those first weeks when you’re on a low dose and you’re wondering if anythi...
110: When To Consider Starting a GLP-1 (Wegovy, Zepbound): Honest Guide for Patients 27.04.2026 33:25
A medication that can support weight loss, lower diabetes risk, and protect your heart sounds almost too good to be true. So we get practical about the real decision: not “Do I want a GLP-1?” but “What problem am I trying to solve?” If the goal is better metabolic health, less sleep apnea burden, improved blood pressure, or a long-term plan for obesity as a chronic disease, the conversation change...
109: Why Your Weight Is Creeping Up (And What To Do About It) 20.04.2026 46:10
Ten extra calories a day. That’s it. That’s the kind of razor-thin margin that can quietly add a pound a year and it’s why so many people swear they “didn’t change anything” while the scale slowly drifted upward. We unpack the simple math behind the one pound rule, what the research shows across decades, and why the real story is rarely one dramatic habit. It’s a stack of tiny shifts: a little les...
108: What Actually Happens During a Heart Attack 13.04.2026 12:12
Your heart doesn’t “randomly” decide to have a heart attack, and that one idea can change how you react to symptoms. We sit down and explain, in plain language, what’s happening inside the body when a coronary artery suddenly gets blocked and why the phrase time is muscle is not just a slogan, it’s the whole game. We start with the basics: the heart is a muscle that needs its own oxygen supply, de...
107: A New GLP1 Weight Loss Pill? What You Need to Know About Orforglipron (Foundayo) 06.04.2026 26:46
A GLP-1 that comes as a simple daily pill and can be taken with or without food sounds like a small change, until you think about real life. We’re celebrating two years of Your Checkup and sharing what’s surprised us most, from listeners across the country and around the world to the messages that stick with us, like families changing habits after a heart attack or patients bringing notes back aft...
106: Fatigue: Practical Approach and Ideas for Patients 30.03.2026 33:09
You wake up tired, push through the day tired, and somehow still feel tired after sleeping. That frustrating loop is one of the most common concerns we hear in primary care, and it usually has a pattern. We walk through a simple, clinician-style way to think about fatigue that doesn’t spiral into guesswork: sleep, nutrition, or an underlying medical issue. If you’ve ever wondered whether you’re “j...
105: New Cholesterol Guidelines 2026: What Your Numbers Mean & What to Do 23.03.2026 48:54
Cholesterol advice has been stuck in “it depends” for years, and we wanted something more concrete you can actually use. So we dig into the 2026 American Heart Association cholesterol guidelines and translate them into plain language: the new LDL cholesterol thresholds, what counts as borderline or high, and why having clear targets can make shared decision-making with your doctor, nurse, or PA a...
104: How Smartphones Affect Mental Health: Anxiety, Depression, and Screen Time Explained 16.03.2026 32:11
Your phone might be doing more than stealing time. It may be quietly taxing your mood, your attention, and the basic habits that keep you well. We found a fascinating research study that tested a simple but radical idea: block mobile internet access on a smartphone for two weeks while still letting people call and text, and then measure what changes in mental health, well-being, and focus. We wal...
103: What They Say You Should Actually Eat Everyday 09.03.2026 29:49
Headlines argue. We read the document. This week we unpack the newest dietary guidelines with a clear, practical lens: what the recommendations actually say, why they still look a lot like Mediterranean and DASH patterns, and how to turn them into everyday choices that reduce risk without wrecking joy. We start with the big shift that matters most—focusing on overall dietary patterns instead of ob...
102: 3 Surprising Health Risks You Might Be Ignoring 05.03.2026 16:35
Three ordinary habits—puzzling, pouring, and brushing—carry extraordinary power over long-term health. We unpack new and notable research on cognitive health, colorectal cancer risk, and cardiovascular disease, then turn it into simple actions you can actually keep. First, we explore why puzzles and other structured brain challenges may strengthen executive function, attention, and visuospatial sk...
101: The New (and confusing) Food Pyramid 02.03.2026 27:28
Ever wondered who really decides what America should eat—and how those choices land on your tray at school, your hospital menu, or your family’s grocery list? We take you behind the scenes of the U.S. dietary guidelines, charting the history from the low-fat era and the iconic food pyramid to today’s more pattern-based approach. Along the way, we explore the messy overlap of science, policy, econo...
100: Does Intermittent Fasting Actually Work in 2026? 26.02.2026 22:30
This week on Tasty Tip, we break down three new health stories: • What new research says about intermittent fasting and metabolic health • Why early-onset colon cancer rates are rising • Whether caffeine intake may reduce dementia risk Send us a (voice ) message with this link, we would love to hear from you. Standard message rates may apply. Support the show Production and Content: Edward De...
99: Understanding Your Body Composition: Why the Scale Doesn’t Tell the Whole Story 23.02.2026 35:28
We swap small talk for a deep dive on body composition and why muscle and visceral fat tell a truer health story than the scale. Practical tools like DEXA, bioelectrical impedance, and a simple tape measure help you track what matters and take action. • why body composition beats weight and BMI for risk • what visceral fat is and why it drives inflammation • how muscle improves insulin sensitivity...
98: Menopause, Hormones, & GLP Weight Loss Shots 16.02.2026 24:07
In this episode of Your Checkup , we explore a new study from the Mayo Clinic examining whether menopause hormone therapy enhances weight loss outcomes in postmenopausal women taking tirzepatide. Menopause is a major metabolic turning point — with rising visceral fat, declining muscle mass, and increasing cardiovascular risk. Researchers found that women using hormone therapy while on tirzepatide...
97: The Motivation Checkup: Episode 6: From Motivation to Momentum, How to Turn Insight Into Action 09.02.2026 34:19
This is the final episode of our Motivation Checkup mini-series, and it’s all about turning everything you’ve learned into real, sustainable change. Over the last five episodes, we explored why motivation fades, why willpower isn’t enough, how small habits create lasting progress, what to do when motivation disappears, and how stress, sleep, and burnout sabotage behavior change. In this episode, w...
96: The Motivation Checkup: Episode 5: Motivation vs Habits vs Discipline, What Creates Change 02.02.2026 24:26
In this episode, we break down the difference between motivation, habits, and discipline — three tools people often confuse when trying to change their health. You’ll learn why motivation is great for starting but unreliable for consistency, why habits are the real engine of long-term change, and why discipline is best used as a short-term support, not a lifestyle. We show how relying too much on...
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