UEG Podcast

UEG Podcast is on summer holiday and re-releases published episodes that we think deserve another listen. Enjoy! In this episode, host Egle speaks with former UEG President Axel Dignass about what it takes to lead in times of crisis. Drawing on his experience during the COVID-19 pandemic, Axel reflects on the difference between being a boss and being a true leader. He shares thoughts on the value...

Michael Bretthauer on the real epidemiology of colorectal cancer in the under-50s: a genuine rise from a tiny baseline, the carcinoid confounder inflating the numbers, lifestyle versus genetics, why screening ages shouldn't drop yet, and the ECOPOP trials testing endoscopic resection against surgery.

The 2024 MASLD treatment guidelines are already changing. Pradeep Mundre and Professor Sven Francque (Antwerp), guideline co-author, cover weight-loss targets (7% and 10%), resmetirom in F2-F3 fibrosis, semaglutide's positive phase 3 in MASH, plus pioglitazone, bariatric surgery, and liver transplantation in this population.

Around one in three adults has MASLD, but only a few percent reach cirrhosis. Pradeep Mundre and Professor Sven Francque (Antwerp), co-author of the 2024 EASL guidelines, cover the new nomenclature, dysfunctional adiposity versus BMI, and how to use FIB-4 to decide who needs a hepatologist.

Sphincter-preserving surgery spares most rectal cancer patients a stoma, but hands many of them low anterior resection syndrome (LARS). Three European surgeons join Harald Rosen in discussing follow-up, where transanal irrigation lands, when to involve the gastroenterologist, and where sacral neuromodulation fits.

EoE requires long-term management, but what does that look like in practice? In Part 2, Prof. Alex Straumann discusses the realities of treating a chronic, relapsing disease, where remission is achievable but a cure is not. The episode explores how to approach maintenance therapy, manage persistent symptoms despite histological remission, and when to escalate treatment to biologics. It also addres...

Part 2 will be released on Wednesday, the 29th of April. Eosinophilic oesophagitis (EoE) is now a well-recognised condition. But it was not always so. In this episode, Prof. Alex Straumann shares how EoE was first identified, taking us back to the late 1980s when unusual cases of food impaction and eosinophilic inflammation did not fit any known diagnosis. He discusses the clinical observations th...

In this episode, Pradeep Mundre speaks with Hannah Gordon about one of the most challenging areas in inflammatory bowel disease management: balancing effective treatment with cancer risk. As therapeutic options expand, clinicians increasingly face complex scenarios involving patients with prior malignancy in remission or those undergoing active cancer treatment. The discussion examines how cancer...

Cristian Costas, a leading dietitian in coeliac disease, shares insights on managing celiac disease through diet, setting up specialised services, and navigating dietary challenges. We explore diagnosis, implementation of a gluten-free diet, and strategies to improve patient outcomes.

In the second part of this in-depth conversation, host Egle Dieninyte continues her discussion with Professor Nageshwar Reddy, shifting the focus from technological innovation to ethics, responsibility and the human dimension of endoscopy. Professor Reddy shares how mobile endoscopy units have brought life-saving care to rural populations, and why cascade hygiene strategies are sometimes necessary...

What has truly transformed endoscopy over the past decades? In this first part of a two-part conversation, host Egle Dieninyte sits down with Professor Nageshwar Reddy, one of the most influential pioneers in modern therapeutic endoscopy, to reflect on how the field has evolved — and where it is heading next. From the transition from rigid to fibreoptic endoscopy, to the introduction of video syst...

- What happens when optical diagnosis and histology don’t align? - Does better polyp detection always mean better outcomes? - And how should AI, quality metrics and surveillance intervals really shape daily endoscopy practice? In this special episode, we share an unfiltered round-table discussion recorded during the UEG Online Course on the impact of polyp detection in colonoscopy. Leading experts...

In this episode of the UEG Podcast, host Pradeep Mundre is joined by David Sanders, Professor of Gastroenterology at Sheffield and one of the world’s leading experts in coeliac disease. Timed with the recent update of the British Society of Gastroenterology coeliac guidelines, the discussion explores why coeliac disease remains frequently underdiagnosed, even in specialist care. Together, they unp...

Immunotherapy might be revolutionising the way we fight GI cancers. In our latest episode, we dive into how this innovative treatment is changing patient outcomes and the role it plays in cancer management. To discuss this, we talked to Jeroen Dekervel, gastroenterologist and oncologist at the UZ Leuven in Belgium. Our host, Pradeep Mundre guides us through the conversation about how tumours devel...

In this thought-provoking episode of the UEG Podcast, host Egle Dieninyte sits down with organisational psychologist Lina Sopiene to explore one of medicine’s most unspoken challenges — burnout. Together, they unpack why high-achieving healthcare professionals often equate self-worth with performance, how this mindset fuels exhaustion, and what practical steps can help doctors and nurses reconnect...

This episode of the UEG Podcast takes place at the EPC meeting in the summer of 2025. Our host Egle Dieninyte sits down with Professor Marco Del Chiaro, Surgical Oncologist and global lead of the upcoming Guidelines on Pancreatic Cystic Neoplasms. Tune in as they discuss why a unified, evidence-based approach is essential in this complex field, the challenges of managing cystic pancreatic lesions...

In this episode of the UEG Podcast, Mary Phillips and Leigh Donnelly reflect on the highlights of UEG Week 2025 in Berlin from a nursing and allied healthcare perspective. They discuss the most inspiring sessions from learning through mistakes in “Never Waste a Good Disaster” to the growing focus on sustainability, green endoscopy, and global health. The conversation also touches on caring for tra...

In this episode, UEG's new Scientific Committee chair Jörn Schattenberg and Carolin Schneider, UEG rising start of 2025, recap the standout science from UEG Week 2025 in Berlin. They discuss highlights from the HPB field, including pivotal phase III data on linerixibat for cholestatic pruritus in PBC, advances in MASLD/MASH therapies such as FGF21 analogues and resmetirom, and new insights into li...

In this episode of the UEG Podcast, our host Pradeep Mundre, together with IBD expert Klaartje Bel Kok, explore the latest breakthroughs in IBD presented at UEG Week 2025 in Berlin. From long-term IL-23 inhibitor data to novel drugs such as Obefazimod and Tulisokibart, the discussion covers key findings that are reshaping IBD management. Bel dives into new insights on JAK inhibitors in pregnancy,...

Join Julia Mayerle and Francisco X. Real (Paco) as they reflect on the first-ever Digestive Disease Mechanism (DDM) Summit, introduced during UEG Week 2025 in Berlin. In this special episode, they discuss how the DDM Summit brought together leading scientists and clinicians to explore the mechanisms driving GI cancers — from colorectal to pancreatic and liver cancer. Hear how cutting-edge discover...

In this episode, host Eglė is joined by Manmeet Matharoo (St Mark’s Hospital, London) to reflect on the highlights of UEG Week 2025 in Berlin from an endoscopy perspective. Together, they discuss the shift towards precision endoscopy, smarter patient and lesion selection, and the philosophy of “treat the patient, not the polyp.” The conversation explores how concepts such as cold-snare resection,...

Our hosts Egle and Pradeep take you back to UEG Week 2024 in Vienna, where they spoke with visitors from across the globe. Discover their impressions, experiences, and highlights — from career-boosting opportunities to inspiring scientific sessions and the vibrant community spirit. Tune in and get ready for what awaits at UEG Week 2025 in Berlin. Don’t miss the chance to hear why participants call...

How can we ensure young patients with chronic digestive and liver diseases move safely and smoothly from paediatric to adult care? In this episode, Pradeep speaks with Professor Patrizia Burra (University of Padua, Italy; Chair of UEG Public Affairs Group) and Dr Jorge Amil Dias (Hospital Lusíadas, Porto, Portugal; ESPGHAN representative in UEG Public Affairs Committee).

In this episode of UEG Talks, host Egle and co-host Charles Murray sit down with Alexander Goldowsky, a gastroenterologist and gut microbiome expert, to explore the unique healthcare challenges faced by sexual and gender minority (SGM) groups. They discuss the stigma and discrimination that impact SGM patients, the broader implications for their health, and the urgent need for greater awareness, e...

During the summer holidays, UEG Talks re-releases older episodes: In this episode of UEG Talks, host Pradeep Mundre is joined by two experts in AI applications for endoscopy: Louis Lau from the Chinese University of Hong Kong and Alanna Ebigbo from the University Hospital in Augsburg. In the first part of the episode, they discuss the basic concepts of AI and its utility in the upper GI tract.