The Pharm So Hard Emergency Medicine & Hospital Pharmacy Podcast

In this episode of the Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, is joined by Brian Gilbert, PharmD, MBA, FCCM, FNCS, FCCP, FASHP, FKCHP, Heather Blue, PharmD, BCPS, FMSHP, BCEMP, Alyssa Robertson, PharmD, BCPS, BCCCP, BCEMP, and David Zimmerman, PharmD, BCCCP, BCEMP, FASHP, FCCP, to discuss one of the most pressing operational challenges facing emergency medicine pharm...

In Episode 130 of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, is joined by Hunter Rondeau, PharmD, BCIDP, AAHIVP, antimicrobial stewardship coordinator at SSM Health, to explore the growing role of single-dose aminoglycosides for urinary tract infections with limited oral treatment options. Hunter shares how this strategy gained traction through emergency department c...

In Episode 129 of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, is joined by Oscar Santalo, PharmD, MBA, MHA, BCPS, to discuss his recently published study in the Journal of Acute Care Pharmacotherapy (JACP) examining prescription abandonment after emergency department discharge. Jimmy and Oscar walk through the motivation behind the research and explore how automated p...

In Episode 128 of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, takes on one of the most common—and most consequential—errors in emergency care: how we give IM epinephrine for anaphylaxis. Spoiler alert: if you’re giving it in the arm, you may be giving your patient little more than saline. Using real EMS-to-ED scenarios and landmark pharmacokinetic data, Jimmy breaks d...

In Episode 127 of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, breaks down the long-awaited RSI Trial comparing ketamine versus etomidate for rapid sequence intubation in critically ill patients. Challenging more than two decades of dogma, Jimmy explores why ketamine was associated with more early cardiovascular collapse—including higher rates of vasopressor escalation...

Picking up right where Part 1 left off, this episode zeroes in on the practical, high-stakes side of inpatient heart failure management. Dr. Cait Kulig returns to unpack key adverse effects of diuresis, strategies to overcome diuretic resistance, and how to approach add-ons, IV vasoactive agents, and inotropes. Jimmy and Cait also dive into the impact of acute decompensated heart failure on pharma...

In Part 1 of this two-part masterclass on acute heart failure, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, teams up with Cait E. Kulig, PharmD, HF-Cert, clinical cardiology expert and creator of CAR Rx Explain , to unpack the fundamentals of heart failure in a way that finally clicks. From defining heart failure and understanding ejection fraction to breaking down volume status and the Forreste...

In Episode 124 of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, explores the ongoing debate around anticoagulation reversal in patients with minor traumatic intracranial hemorrhage (TICH). Highlighting a recent multicenter study, Jimmy breaks down the data, challenges current guideline-driven practices, and raises critical questions about risk, patient selection, and cl...

In this episode of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, introduces the Society of Emergency Medicine Pharmacists (SEMP), a newly established organization dedicated to advancing the practice of emergency medicine pharmacy. Jimmy discusses SEMP's mission to optimize pharmacotherapeutic care in emergency departments through practice improvement, education, advocac...

In this episode of The Pharm So Hard Emergency Medicine Podcast , host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, explores the potential of SGLT2 inhibitors in critically ill patients with guest Daniella Abi Kheir, PharmD. Traditionally viewed as diabetes medications, SGLT2 inhibitors are now gaining attention for their pleiotropic effects, including cardiovascular, renal, and anti-inflammatory ben...

In this episode of The Pharm So Hard Emergency Medicine Podcast , host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, is joined by William Amarquaye, PharmD, to discuss Journavix, the first non-opioid pill approved for moderate to severe acute pain in over 20 years. They break down its mechanism as a NAV1.8 sodium channel blocker, compare it to existing analgesics, and analyze clinical trial data on it...

Episode 120. Ketamine for Benzodiazepine-Resistant Status Epilepticus – A Game-Changer? In this episode of The Pharm So Hard Emergency Medicine Podcast , host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP dives deep into an exciting new study exploring ketamine as a rescue agent for benzodiazepine-resistant status epilepticus. Traditionally, managing refractory seizures often requires intubation, high-...

In Episode 119 of The Pharm So Hard Emergency Medicine Podcast , Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, dives into the COPY-ED study, which explores cephalosporins as a viable option for treating outpatient pyelonephritis. Jimmy challenges the fluoroquinolone-dominant narrative, breaks down the study’s methods and results, and highlights the implications for emergency medicine pharmacists.   ★...

In this episode of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, and guest Rosa Malloy-Post, MD, delve into the debate over the most suitable paralyzing agent for rapid sequence intubation (RSI). They weigh the advantages and disadvantages of Succinylcholine ("Succ") and Rocuronium ("Roc") by comparing their pharmacologic properties, onset, duration, side effects, and c...

In this episode, host Jimmy L. Pruitt III, PharmD, BCPS, BCCCP, BCEMP, welcomes Tessa R. Cox, PharmD, BCCCP, and Brian W. Gilbert, PharmD, MBA, FCCM, FNCS, BCCCP, to discuss their study on the early administration of subcutaneous (SQ) basal insulin in mild to moderate diabetic ketoacidosis (DKA). The episode covers the definition and treatment of DKA, the role of insulin therapy, and the design an...

Amazon Link: https://www.amazon.com/InteGREAT-Guidebook-Creating-Healthcare-Teams/dp/1946665706 In this episode, Jimmy Pruitt engages with the C3 Group authors, Andrea Sikora, Anthony Hawkins, and Susan Smith from the University of Georgia College of Pharmacy. They delve into their collaborative journey of writing the book InteGREAT: A Guidebook for Creating Great Healthcare Teams . The discussion...

This episode of the Pharm So Hard podcast discusses the use of clinical pharmacy practitioners in the emergency room and their impact on sepsis antibiotic interventions author by Aubrie Hammond, Regan Porter, Taylor Cason, et al. The study found that the involvement of EMCPPs significantly improved the selection and timing of antibiotic administration in septic patients. The pharmacist-driven prot...

In this episode of the Pharm So Hard Podcast's PharmD Literature Highlight Series, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP discusses the study "Risk of arrhythmia in post-resuscitative shock after out-of-hospital cardiac arrest with epinephrine versus norepinephrine" by Sarah Normand, Pharm. D., Courtney Matthews, Pharm. D., Caitlin S. Brown, Pharm. D., Alicia E. Mattson, Pharm. D., Kristin...

Full Text PubMed In this episode of the Pharm So Hard podcast, host Jimmy Pruitt interviews Brock Townsend and Brian Gilbert about their study on the impact of time to administration of four-factor PCC for patients with warfarin-associated intracranial hemorrhage. The study was a retrospective observational single-center study performed at a large community teaching hospital. The authors stratifie...

In this episode of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, alongside guests Robert O'Connell, PharmD, BCCCP, BCEMP, Louisa Sullivan, PharmD, BCPS, BCEMP, Mark Mixon, PharmD, BCPS, BCIDP, BCCCP, and Joshua Senn, PharmD, BCPS, share their experiences at last year's EMPoweRx conference. As they gear up for this year's conference, gain exclusive insights into their preparati...

This Pharm So Hard episode titled "Pulse Check! Kyle Stupca's Study on Esmolol & Dose-Capped Epi" is a deep dive into the innovative research conducted by Kyle Stupca on emergency cardiac care. The episode hosted by Jimmy Pruitt aims to explore Stupca's groundbreaking study which focuses on the use of Esmolol and dose-capped epinephrine in treating life-threatening cardiac arrhythmias like ven...

In this episode of the Pharm So Hard Podcast, Jimmy L. Pruitt III, PharmD, BCPS, BCCCP together with Alexandra Cruz Pabón, PharmD and Nicholas Servati, PharmD, BCCP discuss the STREAM-2 Study Journal Club. ★ Support this podcast ★

In this episode of the Pharm So Hard Podcast, Jimmy L. Pruitt III, PharmD, BCPS, BCCCP together with Rosa Malloy-Post, MD discuss the use of Methylene Blue for Refractory Hypotension. ★ Support this podcast ★

In this episode of the Pharm So Hard Podcast, Jimmy L. Pruitt III, PharmD, BCPS, BCCCP together with Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES and Sarah Cummins, PharmD discuss everything about DEI, Transparency, and Advocacy in Pharmacy Organizations. ★ Support this podcast ★

In this episode of the Pharm So Hard Podcast, Jimmy L. Pruitt III, PharmD, BCPS, BCCCP together with Thom Maciulewicz, PharmD, BCPS talk everything about Bupropion. ★ Support this podcast ★