The NatureCity Podcast

Most sleep supplements were built around one idea: make you sleepy. But if you have ever felt tired but wired at bedtime, you already know that making yourself drowsy does not guarantee a good night's sleep. In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, explains why modern sleep support has to do more. Carl co-founded NatureCity over 20 years ago with his wife, Beth, and the co...

Most people meet vitamin K2 through bone health. The less known story is what it does for your arteries. Subscribe for science-backed healthy-aging answers from Carl Pradelli. Most of the vitamin K in your diet is K1, not K2, and the two do not behave the same way in the body. That distinction is the whole episode. Carl Pradelli, CEO and Co-Founder of NatureCity, walks through why vitamin K2 in th...

Some magnesium supplements look impressive on the label — especially those claiming large amounts of magnesium from a “complex” of multiple forms. But when you break down the math, many of these products appear to rely overwhelmingly on magnesium oxide : the cheapest, least absorbable, and often least desirable form for everyday supplementation. In this episode, Carl Pradelli, CEO and Co-Founder o...

Many people reach for glucosamine or chondroitin when they think about joint supplements. The ingredient with some of the strongest human research behind it comes from a part of the egg almost everyone throws away: the thin membrane inside the shell. Carl Pradelli, CEO and Co-Founder of NatureCity, breaks down natural eggshell membrane, known as NEM, and why it may be one of the most underapprecia...

Amla is everywhere in haircare right now—but what does the science actually support? Carl Pradelli breaks down what this trending ingredient does best. WHAT YOU'LL LEARN Why amla (Indian gooseberry) is trending in beauty and haircare circles What the early human research says about amla and hair health The stronger scientific evidence linking amla to cardiovascular support How Capros amla extract...

Most women don't think about bone health until their 60s or 70s — and by then, bone loss is already well underway. Subscribe to the NatureCity channel for science-backed conversations on supplements, healthy aging, and the research most women never hear. In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, walks through why bone health support has to start earlier than most women real...

Most collagen advice stops at the supplement aisle. Subscribe for what comes next: https://www.youtube.com/@naturecitysupplements In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, walks through what the body actually does with collagen peptides — and the five nutrients that turn those fragments into actual collagen for healthy skin, hair, joints, and connective tissue. Collagen is...

Turmeric and curcumin are not the same thing — and most curcumin supplements are poorly absorbed. Subscribe for more supplement truth from Carl Pradelli. In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, breaks down the real reason so many curcumin supplements underperform: absorption. The milligram number on the bottle is only half the story. What matters is how much your body can...

Struggling to stay focused without reaching for another cup of coffee? Carl Pradelli, CEO and Co-Founder of NatureCity, explains why stimulation is not the same as focus and how calming energy can transform your productivity. WHAT YOU'LL LEARN ✓ Why caffeine creates short energy spikes followed by crashes that hurt focus ✓ What "calming energy" means and why it outperforms stimulation for sustaine...

Is your magnesium supplement actually what it claims to be? Carl Pradelli, CEO and Co-Founder of NatureCity, breaks down the critical difference between magnesium glycinate and magnesium bisglycinate chelate so you stop wasting money on supplements that may look good on the label but don’t deliver. Subscribe for weekly supplement truths. WHAT YOU’LL LEARN ✓ Why magnesium glycinate and magnesium bi...

Hair thinning and excess shedding are common concerns — but can targeted nutrition help? In this episode of the NatureCity Podcast, Carl Pradelli breaks down a new placebo-controlled study evaluating plant-based biotin (RGen-Bio®) and silica (RGgen-Si™), and their impact on hair loss, hair growth, thickness, and overall appearance. Plus, you’ll see how these nutrients helped skin and nails too. Yo...

Your body runs on cellular energy, and your cells constantly need to produce new energy. In the last episode, we explored how ubiquinol, the active form of CoQ10, supports heart health by fueling the massive energy demands of the heart. But the heart is not the only organ that relies heavily on cellular energy. In this episode of the NatureCity Podcast, CEO and co-founder Carl Pradelli expands the...

Your heart beats 100,000 times a day and pumps up to 10 tons of blood — but most people never think about the energy it takes to keep it going. In this American Heart Month episode, NatureCity CEO and co-founder Carl Pradelli breaks down the critical connection between heart health and cellular energy — and explains why ubiquinol, the active form of CoQ10, may be the most overlooked supplement for...

In this episode of the NatureCity Podcast , host and supplement expert Carl Pradelli welcomes back Dr. Karen Hecht , Vice President of Science at AstaReal , along with Dr. Susan Hamrahi , who leads scientific communications. Astaxanthin has long been recognized as one of nature’s most powerful antioxidants — but since Carl and Dr. Hecht’s original deep dive in Episode 9, a wave of new human resear...

In this episode of the NatureCity Podcast , host and supplement expert Carl Pradelli breaks down a newly published study that takes a deeper — and more impactful — look at omega-3s and brain health. Rather than relying on food questionnaires or supplement surveys, this new research measured omega-3 blood levels , offering a clearer picture of how EPA and DHA status relates to the earliest biologic...

In this episode of the NatureCity Podcast , host and supplement expert Carl Pradelli breaks down a newly published human study on resveratrol — and why its findings go beyond skin-deep benefits. Resveratrol has long been discussed for its role in healthy aging, heart health, and longevity. But this new research shifts the spotlight to something many people notice first as they age: visible changes...

In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli takes a step back from the hype surrounding cutting-edge longevity supplements to ask a more practical — and important — question: Do you really need expensive, trendy longevity products to support healthy aging? With longevity now dominating wellness headlines, many supplements promise to slow aging, lengthen telo...

Is your daily coffee helping you… or quietly harming your bones? And could tea actually strengthen them? In this episode of the NatureCity Podcast , host and supplement expert Carl Pradelli revisits a popular question from a past episode: Is caffeine bad for bone health? This time, he breaks down new research published in late 2025 that followed nearly 10,000 women over age 65 for a decade — revea...

Joint discomfort, sore muscles, restless nights, and being overwhelmed by daily stress seem like separate challenges — but did you know your body naturally makes a nutrient that offers support for all of them? In this episode of the NatureCity Podcast , host and supplement expert Carl Pradelli takes a deep dive into PEA (palmitoylethanolamide) —a naturally occurring fatty compound your body uses t...

Skin creams and serums can only do so much to keep your skin and hair looking their best. Support starts from within your body. This is especially true when it comes to reinforcing your skin’s moisture barrier and protecting hair cuticles with ceramides. In this episode of the NatureCity Podcast , host and supplement expert Carl Pradelli introduces Ceramosides® —a plant-based, gluten-free ceramide...

Fraudulent products are a real concern for supplement buyers.   The latest example of this was revealed in lab testing of top selling berberine supplements purchased on Amazon.  The results were pretty shocking with the majority of supplements seemingly containing less than 10% of the berberine claimed on the product label – with a couple containing none at all. In this eye-opening episo...

A new study sponsored by the American Heart Association links long-term melatonin use to increased risk of heart failure and early death—but is the data trustworthy?  What does this mean for supplement users? In this episode, Carl Pradelli breaks down the controversial melatonin study making headlines and the potential issues with how the study was conducted.   Carl also shares his...

In this episode of The NatureCity Podcast , host Carl Pradelli, CEO and co-founder of NatureCity, explores the benefits of one of the best probiotic strain options available for supplements.  It’s a strain of Bacillus subtilis called DE111®. Carl explains how your gut is estimated to contain more than 100 trillion bacteria, which is why supplementing with a diverse group of probiotic strains...

Finding the right supplements and a brand you can trust can feel overwhelming. How do you know which ones truly care about your health? In this episode of the NatureCity Podcast, host and CEO Carl Pradelli shares his 3rd essential tip for buying dietary supplements: know who owns and runs the brand - and why the brand exists. Carl explains why transparency, integrity, and experience matter more th...

Staying active is key to good health.  But it’s hard to do if your muscles don’t recover quickly and soreness lingers. New scientific evidence shows how OptiMSM can help your body recover faster. In this episode of the NatureCity Podcast, host and CEO Carl Pradelli dives into the latest research with OptiMSM, which is a premium form of MSM (methylsulfonylmethane). Find out how this sulfur-ric...