Ben Courchia MD & Daphna Yasova Barbeau MD

The Incubator's Journal Club

Health EN ↓ 162 episodes

The Incubator’s Journal Club is a weekly podcast dedicated to reviewing the latest evidence published in peer-reviewed journals in neonatology and perinatal medicine. Each episode breaks down important studies in newborn and perinatal care, with a clear focus on methodology, key findings, and real-world clinical impact. Designed for clinicians, nurses, and trainees, this series highlights research that meaningfully informs bedside practice and clinical decision-making. It is an efficient and reliable way to stay current with the most relevant and practice-changing evidence in neonatal care.

Author

Ben Courchia MD & Daphna Yasova Barbeau MD

Episodes

#352 - [Journal Club Shorts] - 📌 What Are Outcomes for Infants Born at 22–23 Weeks Across 11 Countries? 01.01.2026 12:57

Outcomes of Preterm Infants Born at 22 to 23 Weeks' Gestation in 11 International Neonatal Networks. Isayama T, Norman M, Kusuda S, Reichman B, Lehtonen L, Lui K, Adams M, Vento Torres M, Filippi L, Battin M, Guinsburg R, Modi N, Håkansson S, Klinger G, de Almeida MF, Helenius K, Bassler D, Su YC, Shah PS; International Network for Evaluation of Outcomes (iNeo) Investigators. JAMA Pediatr. 20...

#331 - [Journal Club Shorts] - 📌 First Use of Patient Specific In Vivo Gene Editing for CPS1 Deficiency 01.01.2026 8:04

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease. Musunuru K, Grandinette SA, Wang X, Hudson TR, Briseno K, Berry AM, Hacker JL, Hsu A, Silverstein RA, Hille LT, Ogul AN, Robinson-Garvin NA, Small JC, McCague S, Burke SM, Wright CM, Bick S, Indurthi V, Sharma S, Jepperson M, Vakulskas CA, Collingwood M, Keogh K, Jacobi A, Sturgeon M, Brommel C, Schmaljohn E, Kurgan G, Osborne...

#331 - [Journal Club Shorts] - 📌 School Performance After Neonatal HIE Through Early Adolescence 01.01.2026 11:41

School outcomes after HIE: a population-based cohort study. Rees P, Dronavalli M, Carter B, Bajuk B, Burns L, Dickson M, Eastwood J, Hossain S, Lawler K, Lee E, Munasinghe S, Page A, Uebel H, Dicair L, Green C, Gale C, Oei JL.Arch Dis Child Fetal Neonatal Ed. 2025 Jun 8:fetalneonatal-2024-328346. doi: 10.1136/archdischild-2024-328346. Online ahead of print. PMID: 40484626 Support the show As alway...

#331 - [Journal Club Shorts] - 📌 Early Full Enteral Nutrition with Fortified Milk in Very Preterm Infants 01.01.2026 20:46

Early full enteral nutrition with fortified milk in very preterm infants: a randomized clinical trial. Salas AA, Gunawan E, Jeffcoat S, Nguyen K.Am J Clin Nutr. 2025 May;121(5):1117-1123. doi: 10.1016/j.ajcnut.2025.02.019. Epub 2025 Feb 21.PMID: 39986385 Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can...

#331 - [Journal Club Shorts] - 📌 Three Neonatal Complications Strongly Associated with Adverse Long Term Outcomes 01.01.2026 12:33

Association of a Count of Inpatient Morbidities with 2-Year Outcomes among Infants Born Extremely Preterm. Dorner RA, Li L, DeMauro SB, Schmidt B, Zangeneh SZ, Vaucher Y, Wyckoff MH, Hintz S, Carlo WA, Gustafson KE, Das A, Katheria A; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr. 2025 Mar;278:114428. doi: 10.1016/j.jpeds.2024....

#331 - [Journal Club Shorts] - 📌 Extended Caffeine Treatment in Moderately Preterm Infants Does Not Shorten Hospital Stay 01.01.2026 11:11

Extended Caffeine for Apnea in Moderately Preterm Infants: The MoCHA Randomized Clinical Trial. Carlo WA, Eichenwald EC, Carper BA, Bell EF, Keszler M, Patel RM, Sánchez PJ, Goldberg RN, D'Angio CT, Van Meurs KP, Hibbs AM, Ambalavanan N, Cosby SS, Newman NS, Vohr BR, Walsh MC, Das A, Ohls RK, Fuller J, Rysavy MA, Ghavam S, Brion LP, Puopolo KM, Moore R, Baack ML, Colaizy TT, Baserga M, Osman...

#331 - [Journal Club Shorts] - 📌 Clinical Recommendations for Imaging and Follow Up of Perinatal Urinary Tract Dilation 01.01.2026 7:18

Perinatal Urinary Tract Dilation: Recommendations on Pre-/Postnatal Imaging, Prophylactic Antibiotics, and Follow-up: Clinical Report. Anthony Herndon CD, Otero HJ, Hains D, Sweeney RM, Lockwood GM; Section on Urology; Section on Nephrology; Section on Radiology; Section on Hospital Medicine. Pediatrics. 2025 Jul 1;156(1):e2025071814. doi: 10.1542/peds.2025-071814.PMID: 40518141 Review. Support th...

#331 - [Journal Club Shorts] - 📌 Higher Carbon Dioxide Thresholds for Late Permissive Hypercapnia in Preterm Infants 01.01.2026 15:02

Late Permissive Hypercapnia for Mechanically Ventilated Preterm Infants: A Randomized Trial. Travers CP, Gentle SJ, Shukla VV, Aban I, Yee AJ, Armstead KM, Benz RL, Laney D, Ambalavanan N, Carlo WA.Pediatr Pulmonol. 2025 Jun;60(6):e71165. doi: 10.1002/ppul.71165.PMID: 40525736 Free PMC article. Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to...

#331 - 📑 Journal Club - The Complete Episode from July 20th 2025 01.01.2026 1:22:47

In this week’s Journal Club, Ben and Daphna dive into several impactful neonatal studies shaping today’s clinical decisions. The discussion opens with the MOCA Trial, exploring whether extending caffeine therapy in moderately preterm infants reduces hospital stays and improves outcomes. Despite reducing apnea episodes, the study highlights that extending caffeine treatment does not reduce time to...

#341 - [Journal Club Shorts] - 📌 EBNEO: Is Therapeutic Hypothermia Beneficial to Infants Born Between 33 and 35 Weeks Gestation? 01.01.2026 16:40

Whole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants 33 to 35 Weeks' Gestation: A Randomized Clinical Trial. Faix RG, Laptook AR, Shankaran S, Eggleston B, Chowdhury D, Heyne RJ, Das A, Pedroza C, Tyson JE, Wusthoff C, Bonifacio SL, Sánchez PJ, Yoder BA, Laughon MM, Vasil DM, Van Meurs KP, Crawford MM, Higgins RD, Poindexter BB, Colaizy TT, Hamrick SEG, Chalak LF, Ohls RK, Ha...

#341 - [Journal Club Shorts] - 📌 New Fenton Growth Charts! 01.01.2026 11:49

Fenton Third-Generation Growth Charts of Preterm Infants Without Abnormal Fetal Growth: A Systematic Review and Meta-Analysis. Fenton TR, Elmrayed S, Alshaikh BN.Paediatr Perinat Epidemiol. 2025 Jun 19. doi: 10.1111/ppe.70035. Online ahead of print. PMID: 40534585 Review. Birth weight and head circumference for 22-29 weeks gestation neonates from an international cohort. Fenton TR, Alshaikh B, Kus...

#341 - [Journal Club Shorts] - 📌 Does ROP Signal Brain Injury in Preterm Infants? 01.01.2026 12:17

Retinopathy of Prematurity and Risk of Structural Brain Abnormalities on Magnetic Resonance Imaging at Term Among Infants Born at Less Than or Equal to 32 Weeks of Gestation. Roy S, Peterson L, Kline-Fath B, Parikh NA; Cincinnati Infant Neurodevelopment Early Prediction Study (CINEPS) Investigators. J Pediatr. 2025 Jun 27;286:114711. doi: 10.1016/j.jpeds.2025.114711. Online ahead of print. PMID: 4...

#341 - [Journal Club Shorts] - 📌 Should you resuscitate preemies with 100% O2 during DCC? 01.01.2026 10:56

Deferred Cord Clamping With High Oxygen in Extremely Preterm Infants: A Randomized Clinical Trial. Katheria AC, Ines F, Lee HC, Sollinger C, Vali P, Morales A, Sanjay S, Dorner R, Koo J, Gollin Y, Das A, Poeltler D, Steinhorn R, Finer N, Lakshminrusimha S.JAMA Pediatr. 2025 Jul 21:e252128. doi: 10.1001/jamapediatrics.2025.2128. Online ahead of print. PMID: 40690234 Support the show As always, feel...

#341 - [Journal Club Shorts] - 📌 Can Autologous Cord Blood Improve Neurodevelopment in the Extremely Preterm? 01.01.2026 14:16

Early Neurodevelopment of Extremely Preterm Infants Administered Autologous Cord Blood Cell Therapy: Secondary Analysis of a Nonrandomized Clinical Trial. Zhou L, Razak A, McDonald CA, Yawno T, McHugh DT, Whiteley G, Connelly K, Sackett V, Miller SL, Jenkin G, Novak I, Hunt RW, Malhotra A.JAMA Netw Open. 2025 Jul 1;8(7):e2521158. doi: 10.1001/jamanetworkopen.2025.21158.PMID: 40608334 Free PMC arti...

#325 - [Journal Club Shorts] - 📌 Severe Neonatal Morbidity and Mortality Through Adolescence 01.01.2026 16:38

Severe Neonatal Morbidity and All-Cause and Cause-Specific Mortality Through Infancy and Late Adolescence. Graham H, Johansson K, Persson M, Norman M, Razaz N.JAMA Pediatr. 2025 Jun 10:e251873. doi: 10.1001/jamapediatrics.2025.1873. Online ahead of print. PMID: 40493844 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can...

#325 - [Journal Club Shorts] - 📌 Prone Positioning in Preterms: Hypoxemia and Feeding 01.01.2026 11:55

Prone Positioning Was Associated With Less Hypoxemic Events and Improved Feeding Tolerance in Preterm Infants. Bohnhorst B, Lutz E, Pirr S, Peter C, Böhne C.Acta Paediatr. 2025 May 26. doi: 10.1111/apa.70153. Online ahead of print. PMID: 40418109 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show t...

#325 - [Journal Club Shorts] - 📌 Prophylactic Hydrocortisone and Sepsis Risk 01.01.2026 15:03

Prophylactic hydrocortisone and the risk of sepsis in neonates born extremely preterm. Baud O, Lehert P; PREMILOC study group. Eur J Pediatr. 2025 Jun 14;184(7):419. doi: 10.1007/s00431-025-06248-9.PMID: 40515786 Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram o...

#325 - [Journal Club Shorts] - 📌 Teleneonatology and Hypothermia Timing 01.01.2026 12:55

Impact of teleneonatology on time to goal temperature in outborn neonates with hypoxic-ischemic encephalopathy requiring therapeutic hypothermia. Kaczor M, Hentz R, Youssef PE, Fine A, Fang J.J Perinatol. 2025 May 29. doi: 10.1038/s41372-025-02324-y. Online ahead of print. PMID: 40442292 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@...

#325 - [Journal Club Shorts] - 📌 Cold Milk for Infants with Feeding Challenges 01.01.2026 15:14

From Warm to Cold: Feeding Cold Milk to Preterm Infants with Uncoordinated Oral Feeding Patterns. Ferrara-Gonzalez L, Kamity R, Htun Z, Dumpa V, Islam S, Hanna N.Nutrients. 2025 Apr 26;17(9):1457. doi: 10.3390/nu17091457.PMID: 40362766 Free PMC article. Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can...

#325 - [Journal Club Shorts] - 📌 Norepinephrine vs. Dopamine in Neonatal Septic Shock 01.01.2026 12:51

Norepinephrine versus Dopamine for Septic Shock in Neonates: A Randomized Controlled Trial. Mazhari MYA, Priyadarshi M, Singh P, Chaurasia S, Basu S.J Pediatr. 2025 Jul;282:114599. doi: 10.1016/j.jpeds.2025.114599. Epub 2025 Apr 17.PMID: 40252959 Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also co...

#325 - [Journal Club Shorts] - 📌 Kangaroo Care vs. Conventional Care Meta-Analysis 01.01.2026 6:12

All-cause mortality and infection-related outcomes of hospital-initiated kangaroo care versus conventional neonatal care for low-birthweight infants: a systematic review and meta-analysis. Minotti C, Jost K, Aghlmandi S, Schlaeppi C, Sieswerda E, van Werkhoven CH, Schulzke SM, Bielicki JA.Lancet Child Adolesc Health. 2025 Jul;9(7):470-483. doi: 10.1016/S2352-4642(25)00130-0. Epub 2025 May 26.PMID:...

#325 - 📑 Journal Club - The Complete Episode from June 29th 2025 01.01.2026 1:25:33

In this week’s Journal Club, Ben and Daphna unpack a series of recent studies exploring outcomes in neonatology—from long-term mortality after severe neonatal morbidity to short-term feeding strategies in preterm infants. They open with a large population-based Swedish study showing that infants who experience severe neonatal morbidities face elevated mortality risks well into adolescence—especial...

#317 - [Journal Club Shorts] - 📌 The AAP Report on diagnosis and treatment of the PDA 01.01.2026 31:58

Patent Ductus Arteriosus in Preterm Infants. Ambalavanan N, Aucott SW, Salavitabar A, Levy VY; Committee on Fetus and Newborn; Section on Cardiology and Cardiac Surgery. Pediatrics. 2025 May 1;155(5):e2025071425. doi: 10.1542/peds.2025-071425.PMID: 40288780 Review. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also...

#317 - [Journal Club Shorts] - 📌 The latest meta analysis of early treatment of the PDA 01.01.2026 4:21

Active Treatment vs Expectant Management of Patent Ductus Arteriosus in Preterm Infants: A Meta-Analysis. Buvaneswarran S, Wong YL, Liang S, Quek SC, Lee J.JAMA Pediatr. 2025 May 27:e251025. doi: 10.1001/jamapediatrics.2025.1025. Online ahead of print. PMID: 40423988 Free PMC Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com....

#317 - [Journal Club Shorts] - 📌 🇨🇦 Consensus on Timing of Brain MRI and Classification of Brain Injury after HIE 01.01.2026 13:27

Consensus Approach for Standardization of the Timing of Brain Magnetic Resonance Imaging and Classification of Brain Injury in Neonates With Neonatal Encephalopathy/Hypoxic-Ischemic Encephalopathy: A Canadian Perspective. Mohammad K, Reddy Gurram Venkata SK, Wintermark P, Farooqui M, Beltempo M, Hicks M, Zein H, Shah PS, Garfinkle J, Sandesh S, Cizmeci MN, Fajardo C, Guillot M, de Vries LS, Pinche...