Precision Medicine Made Simple

What happens when a highly motivated patient meets a healthcare system that’s… not built for patients? In this episode, Kathy Giusti joins Taylor Cu and Dr. William Stanford to break down why cancer care can feel impossible to navigate—and what patients can do to take control of decisions, timelines, and outcomes. Kathy shares how her diagnosis pushed her into “research mode,” how she identified t...

In this episode of Precision Medicine Made Simple , we continue our discussion with Dr. Mohammad Jarbou from Episode 33, where we first explored the significance of VO₂ Max testing and its role in personal health optimization. Now, we dive deeper into the importance of sleep health , heart rate variability (HRV) , and the insights provided by sleep studies . Dr. Jarbou breaks down how HRV can be a...

The traditional healthcare system is breaking under the weight of burnout, short appointments, and profit-driven incentives, and Dr. Adam Wheeler has lived it from the inside. After losing a patient and realizing that all his creative energy was going into improving metrics instead of improving lives, he decided to build something radically different. In this episode of Precision Medicine Made Sim...

In this episode of Precision Medicine Made Simple , we’re joined by Dr. Mohammad Jarbou, co-founder of the Longevity Clinic. Dr. Jarbou, a board-certified physician in pulmonary medicine, critical care, sleep medicine, and clinical informatics, discusses how his clinic uses a holistic approach to aging and health span. The clinic focuses on prevention and early detection, utilizing personalized me...

In this episode of Precision Medicine Made Simple , we’re joined by Dr. Jeff Gulcher, co-founder of Decode Genetics and current leader at Galateo Bio. Dr. Gulcher shares his vast experience in the field of genomics and precision medicine, covering everything from polygenic risk scores (PRS) to the challenges of integrating diverse genetic data into predictive healthcare. Dr. Gulcher takes us back...

In this episode of Precision Medicine Made Simple , we’re joined by Lucy Janoyan , the Chief Operations Officer and Chief Strategy Officer at Biography Health. Together with Taylor Cu, Lucy dives into a wide-ranging discussion on the state of healthcare, DIY testing, and the future of personalized care. Lucy and Taylor reflect on their experience at Rosetta Fest, where they explored the complexiti...

In this episode of Precision Medicine Made Simple , we welcome back Dr. Yelena Bykhovskaya, the Chief Scientific Officer at Biography Health, for a deep dive into polygenic risk scores (PRS) and their emerging role in precision medicine. Dr. Bykhovskaya breaks down the complexities of genetics and its application in clinical practice, focusing on how polygenic risk scores can be used to assess an...

In this episode of Precision Medicine Made Simple , we’re joined by Dr. Rich Joseph, a physician with a rare blend of expertise as both a strength and conditioning specialist and a competitive athlete. Dr. Joseph is the founder of VIM Medicine and the Board Chair of Vital Connections. He’s also a faculty member at Harvard Medical School and Brigham and Women’s Hospital, where he focuses on prevent...

Most of today’s healthcare still treats problems after they happen. Dr. Leroy Hood thinks that needs to change. In this episode of Precision Medicine Made Simple , he explains how genomics, regular health tracking, and AI can shift the focus to preventing disease before it starts. Dr. Hood is one of the scientists who helped build the automated DNA sequencer that powered the Human Genome Project....

What does it really take to solve the medical mysteries most doctors dismiss? In this episode of Precision Medicine Made Simple , we sit down with Dr. Hengameh Monsef, DO, an internal medicine physician trained in high-acuity care, now reinventing how we treat chronic and complex illness through concierge precision medicine at Ascending Medicine. She shares her journey from Iran to the U.S., from...

What if your doctor could predict what will kill you—before it ever becomes a problem? In this episode of Precision Medicine Made Simple , we dive into the evolving landscape of longevity medicine and health AI with Dr. Hillary Lin, Stanford-trained internist, former oncologist, and co-founder of CareCore—a platform empowering wellness creators and brands to offer doctor-supervised, data-driven ca...

In this episode of Precision Medicine Made Simple, hosts Dr. William Stanford and Taylor Cu sit down with Dr. Genise Fraiman, founder of Ascending Medicine and a trailblazer in concierge care. With over two decades of experience—from co-founding one of Cedars-Sinai’s top hospitalist groups to mentoring young physicians—Dr. Fraiman shares her personal and professional evolution toward a more human,...

We’re living in the age of health data overload—but how do you turn all those insights into real-life transformation? This episode of Precision Medicine Made Simple features Dr. Daniel Stickler, former vascular surgeon turned systems medicine pioneer, who’s leading the charge in longevity, AI-powered diagnostics, and cutting-edge clinical tools. In this candid conversation with hosts Dr. Stanford...

The Former ER Doctor Challenging How We Practice Medicine w/Dr. Sukhjit "Sarge" Takhar Primary-MD.com Email: drtakhar@primary-md.com Takeaways Dr. Takhar emphasizes the importance of understanding the patient as a person. Concierge medicine allows for more personalized and attentive care. The healthcare system often limits the time doctors can spend with patients. AI can assist in healthcare but c...

In this episode, Dr. David Moskowitz shares how thousands of patients have avoided dialysis through genomic medicine — and why most kidney failure is preventable. We dive deep into ACE genes, repurposed drugs like quinapril and ProGraph, and explore what genomic insights could mean for diseases like Alzheimer's and cancer. Heads up: this one gets detailed with a lot of medical terminology. If you'...

In this episode, Dr. Stanford, Lucy Janoyan, and Taylor Cu reflect on key takeaways from the Precision Medicine World Conference — from AI’s role in understanding disease to the future of polygenic risk scores. They discuss the challenges of data validity, patient privacy, and the evolving role of patients and providers in a tech-driven healthcare landscape, including a highlight from NVIDIA CEO J...

Podcast Suggestion Survey

When Genes Collide: A Rare Diagnosis Reveals Complex Health Interactions with Dr. Philip Bretsky For this episode, Dr. Bretsky shares a remarkable case study that unravels the complex relationship between genes and inflammation. When a patient's mysterious symptoms led to the rare diagnosis of VEXAS syndrome, it revealed an unexpected connection with cardiovascular health, demonstrating how differ...

Beauty Span and Health Span: Where Aesthetics Meets Longevity with Dr. Cory Goldberg For this episode, we dive deep into the intersection of aesthetics and longevity with Dr. Cory Goldberg, a renowned plastic and craniofacial surgeon. Dr. Goldberg bridges the art of aesthetic medicine with the science of precision medicine, sharing groundbreaking insights on how oxidative stress affects both beaut...

From Flight Medic to Precision Medicine with Dr. Kat Schmolly In this episode, we're joined by Dr. Kat Schmolly. From her adventurous past as an Air Force Flight Medic to her current mission revolutionizing rare disease diagnosis, Dr. Schmolly shares her unique journey into precision medicine. We discuss why bringing personalized care to the frontlines of medicine is crucial, and explore how innov...

A Doctor's Mission: How Dr. Scoles Used Genetics to Transform Patient Care with Dr. Lyndell Scoles In this episode, we explore pharmacogenomics, also known as genetic pharmaceutical profiling with Dr. Lyndell Scoles with MDVIP. He’s an early pioneer in using genetic testing to optimize medication choices. With over 30 years of experience in internal medicine, Dr. Scoles shares how genetic pharmace...

Ep. 15 - Beyond One-Size-Fits-All: The Science of Drug-Gene Interactions with Michelle Beckwith This episode features Michelle "Shelly" Beckwith, a genetics pioneer since the 1990s who worked on the Human Genome Project. She breaks down how pharmacogenetic testing helps optimize medication choices by analyzing how patients' genetic variations affect drug metabolism. The discussion covers testing m...

Genotyping vs. Sequencing: What's the Difference? In this episode, Dr. William Stanford, Dr. Yelena Bykhovskaya and Taylor Cu discuss various genetic testing methods. The conversation compares genotyping, exome sequencing, and whole genome sequencing, with an emphasis on whole genome sequencing, which provides the most comprehensive genetic information. Timestamps: 00:03:22 - Discussion begins on...

In this episode, Dr. Yelena Bykhovskaya, Chief Scientific Officer at Biography Health, shares her expertise in genetics. We explore the importance of both polygenic and monogenic risk scores in patient care. The conversation underscores the value of combining cutting-edge genetic analysis with traditional clinical factors in the evolving field of precision medicine, emphasizing the need for a comp...

How Doctors are Using Genetic Data to Transform Patient Care with Philip Bretsky MD PhD MPH FACP In this episode, we're joined by Dr. Philip Bretsky, a board-certified internist from Santa Monica with expertise in epidemiology and Alzheimer's research. Dr. Bretsky discusses how precision medicine is transforming healthcare by integrating genetics, biomarkers, and lifestyle factors. He explores the...