Pharmacy to Dose: The Critical Care Podcast

Literature Review Series November 2023 Special Guests: Arjay Mendoza, PharmD, BCPS, AAHIVP Brock Townsend, PharmD @Townsend_PharmD   04:30 – Featured Articles 35:25 – Cardiology 48:05 – Precision-based medicine potpourri 58:50 – Infectious Diseases 69:10 – PharmD   Reference List: https://pharmacytodose.files.wordpress.com/2024/04/november-lrs-2023-references.pdf   PharmacyToDose. Com @PharmacyToD...

Trial of the Week: SOAP II Special Guest: Jessica Casey, PharmD, BCPS, BCCP @jmc_cardspharmd   Jessica Casey joins to discuss the April Trial of the Week “Comparison of Dopamine and Norepinephrine in the Treatment of Shock,” the SOAP II study, published in NEJM in 2010. We set the scene by reviewing catecholamine vasopressor receptor physiology, guideline recommendations, and pre-SOAP II research....

Trials of the Week: Landmark Nimodipine Studies Special Guest: Salia Farrokh, PharmD, BCCCP, FNCS @salia_farrokh   Salia Farrokh joins to highlight two landmark studies with nimodipine, “Cerebral Arterial Spasm – A Controlled Trial of Nimodipine in Patients with Subarachnoid Hemorrhage” published in NEJM in 1983 and “Effect of Oral Nimodipine on Cerebral Infarction and Outcome after Subarachnoid H...

Norepinephrine Position Paper and Sepsis Research Priorities Special Guests: Brittany Bissell Turpin, PharmD, PhD, FCCM, BCCCP @BissellBrittany Patrick Wieruszewski, PharmD, BCCCP @pwierusz Seth Bauer, PharmD, FCCM, FCCP, BCCCP @SethRBauer   07:30 – Norepinephrine position paper introduction 11:35 – When did we realize this and what are the implications? 36:00 – Key task force take-aways 51:00 – S...

Final Four Preview and More: 2024 Critical Care Trials March Madness Bracket   Sepsis/Fluids Bracketologist: Clay Small, PharmD, BCCCP CV/Pulm Bracketologist: Jolie Gallagher, PharmD, BCCCP Bleeding/BG Bracketologist: Jason Hecht, PharmD, BCPS, BCCCP, FCCM Neuro/PADIS Bracketologist: Karen Berger, PharmD, FASHP, FCCM, BCPS, BCCCP   06:10 – Region recaps 32:10 – Final Four preview and predictions 4...

Literature Review Series October 2023 Special Guests: Hailey Burns, PharmD @Hailey_rx36 Caitlyn Simonson, PharmD   03:45 – Featured Articles 38:15 – Neuro 50:10 – EM/Tox/Trauma 61:50 – Renal/Endocrine 66:38 – PharmD 70:10 – Sweet Emotion   Reference List: https://pharmacytodose.files.wordpress.com/2024/03/october-lrs-2023-references.pdf   PharmacyToDose. Com @PharmacyToDose PharmacyToDose@Gmail.co...

Sweet 16 Preview and Recap: 2024 Critical Care Trials March Madness Bracket Preview   04:06 – First round recap 13:25 – Second round recap 19:05 – Sweet 16 preview   PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-reference-list-all-regions.pdf   2024 March Madness Bracket: https://pharmacytodose.com/2024/03/17/202...

Pharmacotherapy in the Critically Ill Pregnant Patient: Part II Special Guests: Allison Lankford, MD Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin   04:50 – Obstetric hemorrhage 18:20 – Ectopic pregnancy 22:30 – Hypertensive emergency 28:45 – Pre-eclampsia/eclampsia 35:00 – Lactation considerations 39:35 – Take-home points   Pharmacotherapy “Caring for two in the ICU” articles:...

2024 Critical Care Trials March Madness Bracket Preview: Part II Cardiac/Pulmonary and Sepsis/Fluids Regions   CV/Pulm Bracketologist: Jolie Gallagher, PharmD, BCCCP Sepsis/Fluids Bracketologist: Clay Small, PharmD, BCCCP   PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-reference-list-all-regions.pdf   2024 March...

2024 Critical Care Trials March Madness Bracket Preview: Part I Bleeding/Blood Glucose and Neuro/PADIS Regions   Bleeding/BG Bracketologist: Jason Hecht, PharmD, BCPS, BCCCP, FCCM Neuro/PADIS Bracketologist: Karen Berger, PharmD, FASHP, FCCM, BCPS, BCCCP @karenccrx   PubMed links for all 68 Critical Care March Madness trials: https://pharmacytodose.files.wordpress.com/2024/03/critical-care-trials-...

Trial of the Week: CHAMPION PHOENIX Special Guest: Jack Pluenneke, PharmD, BCCP @JackPluenneke   Jack Pluenneke joins to discuss a March 2024 Trial of the Week, “Effect of platelet inhibition with cangrelor during PCI on ischemic events” the CHAMPION PHOENIX trial, published in 2013 in NEJM.  We review PK/PD advantages with cangrelor, go over the CHAMPION trials, and then highlight why the CHAMPIO...

Corticosteroids in the Critically Ill Special Guest: Andrea Nei, PharmD, BCPS, BCCCP, FCCM @Dre_pharmd   04:40 – Guideline introduction/background 08:35 – Scope/authorship 13:35 – PICO questions/recommendations 14:22 – Sepsis 17:20 – CAP 19:10 – ARDS 21:55 – Research priorities/Take-home points 28:50 – Working with your spouse Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: REDUCE Special Guest: Matt Duprey, PharmD, PhD, BCCCP   Matt Duprey joins to discuss the March Trial of the Week, published in 2018 in JAMA: “The Effect of Haloperidol on Survival Among Critically Ill Adults with a High Risk of Delirium: the REDUCE Randomized Clinical Trial.”   We review the history of antipsychotic pharmacotherapy treatment and prophylaxis in delirium, reviewin...

Pharmacotherapy in the Critically Ill Pregnant Patient: Part I Special Guests: Allison Lankford, MD Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin   08:05 – PK/PD changes 12:50 – Medication safety/Drug information resources 20:15 – Maternal sepsis 33:15 – ARDS 43:15 – PADIS 48:45 – Cardiogenic shock & cardiac arrest 59:00 – VTE   Pharmacotherapy “Caring for two in the ICU” artic...

Trial of the Week: Levetiracetam Rapid IV Push Special Guest: Olivia Morgan, PharmD, BCCCP, BCGP   I’m joined by Olivia Morgan to discuss her first author 2020 Neurocritical Care article entitled “Safety and Tolerability of Rapid Administration Undiluted Levetiracetam.” We review previous administration techniques and discussing how this study came to be before highlighting all the findings from t...

Glycemic Control in the Critically Ill: Part I Special Guest: Traci Grucz, PharmD, BCCCP @tmgrucz   04:50 – ICU hyperglycemia mechanism 09:52 – Background/landmark research 27:00 – Current recommendations 30:25 – Hyperglycemia and hypoglycemia tips/tricks 46:30 – Treatment considerations 54:50 – Take-home points   Reference List: https://pharmacytodose.files.wordpress.com/2024/02/glycemic-control-...

Literature Review Series September 2023 Special Guests: Garrett Terhune, PharmD Caroline Blankemeier, PharmD   04:35 – Featured Articles 32:28 – Pulm 38:35 – PADIS 46:50 – Neuro 53:40 – Trauma 62:00 – PharmD 68:10 – Grab Bag   Reference List: https://pharmacytodose.files.wordpress.com/2024/02/september-lrs-2023-references.pdf   PharmacyToDose. Com @PharmacyToDose PharmacyToDose@Gmail.com Learn mor...

Immunotherapy Part II Special Guest: Matt McKenzie, PharmD, BCCCP @mgm485 04:40 – What is and when do we use immunotherapy? 09:00 – CAR-T cell therapy 15:20 – Standard ICU work-up 21:00 – Cytokine release syndrome (CRS) 35:00 – Immune effector cell-associated neurotoxicity syndrome (ICANS) 51:00 – Immune checkpoint inhibitors 64:30 – Summary and take-home points Reference List: https://pharmacytod...

Burnout and Well-being Special Guest: Brent Reed, PharmD, MS, PhD Candidate 07:25 – How did we get here? 09:05 – Defining and drivers of burnout 18:45 – Is it too late if we're already experiencing? 20:15 – Relationship between well-being and burnout 22:00 – Work:life balance 29:00 – Precepting and teaching 35:25 – Foundation of burnout prevention 38:30 – 5 step process for work design change 50:5...

Literature Review Series August 2023 Special Guests: Katie Rogers, PharmD Eric Johnston, PharmD 04:35 – Featured Articles 39:00 – Sepsis 47:35 – Potpourri 52:45 – Infectious Diseases 61:45 – PharmD 68:15 – Grab Bag Reference List: https://pharmacytodose.files.wordpress.com/2024/01/august-lrs-2023-references.pdf PharmacyToDose. Com  @PharmacyToDose  PharmacyToDose@Gmail.com Learn more about your ad...

2024 SCCM Congress Recap Special Guest: Anthony Hawkins, PharmD, FCCM, BCCCP Conference correspondent Anthony Hawkins returns to recap all the happenings from the 2024 SCCM Congress. We review Phoenix, likes and dislikes from the Convention Center, session highlights, exhibit hall review, favorite session titles, PharmD award winners, and much, more. 2024 SCCM Congress website: https://congress202...

2024 SCCM Congress: Tuesday Special Guests: Karen Berger, PharmD, FASHP, FCCM, BCCCP, BCPS Melanie Smith Condeni, PharmD, FCCM, BCPS, BCCCP Julie Farrar, PharmD, BCCCP Lama Nazer, PharmD, BCPS Joanna Stollings, PharmD, FCCP, FCCM, BCPS, BCCCP Andy Webb, PharmD, BCCCP 03:05: Star Research Presentation: “Effect of Antipsychotics on Agitation in ICU Delirium: Secondary Analysis of a Randomized Trial”...

2024 SCCM Congress: Monday Special Guests: Caitlin Brown, PharmD, BCCCP, FCCM Marilyn Bulloch, PharmD, BCPS, FCCM Kayla Kotch, PharmD, BCCCP 02:55: Marilyn Bulloch discusses her role and experience as a 2024 SCCM Congress co-chair 28:30: Star Research Presentation: “Impact of Early Initiation of Phenobarbital for Alcohol Withdrawal Syndrome in the Critically Ill” featuring Kayla Kotch 39:00: Star...

2024 SCCM Congress: Sunday Special Guests: Judi Jacobi, PharmD, BCCCP, MCCM Blake Robbins, PharmD, MBA, BCCCP 02:45: Quick review of the happenings on Sunday, January 21st from 2024 SCCM Congress 07:20: Star Research Presentation: “Standard vs. Augmented Corticosteroid Dosing in Mechanically Ventilated Patients due to COVID-19” featuring Blake Robbins 22:05: Discussion about the SCCM Glycemic Cont...

2024 SCCM Congress: Saturday The episode starts out with a preview of the 2024 SCCM Congress schedule as the conference starts Sunday, January 21 in Phoenix, AZ 11:25: Then I highlight 3 presentations with Pharmacist speakers from the SCCM Digital Congress Fill the Tank or Squeeze the Pipes? Fluid Administration Over Early Vasopressor Therapy for the Management of Shock with Olivia Marchionda, Pha...