Peptides and Longevity: Redefining Aging and Transforming Health with Dr. Kent Holtorf

Aging may begin in the immune system long before symptoms appear. In this Peptides and Longevity episode, Dr. Kent Holtorf breaks down the science behind peptides, immune balance, inflammation, mitochondrial health, sleep, brain function, and why peptide therapies are being explored as tools to support healing and healthy aging.  - - - - -  Kent Holtorf, MD , is the founder and medical director of...

Fasting isn’t just willpower, it’s a cellular switch. In this Peptides and Longevity episode, nutrition professional Renee Fitton breaks down how fasting mimicking supports deep cellular cleanup, metabolic markers, cravings, and longevity pathways—without the struggle of a traditional water fast. - - - - -  Renee Fitton, MS, RD is a longevity-focused registered dietitian and Director of Education...

What if weight loss isn’t about willpower, but restoring what your body lost along the way? In this episode of Peptides and Longevity , Dave Knapp shares his journey through obesity, type 2 diabetes, GLP-1 therapy, sobriety, and faith, revealing how peptides, lifestyle change, and spiritual surrender reshaped his health and purpose. - - - - -  Dave Knapp is a podcaster and founder of On The Pen, a...

Independent pharmacies are filling prescriptions at a loss, and most people have no idea. In this episode of the Peptides and Longevity Podcast, Dr. Lisa Faast breaks down why margins are getting crushed, what clinicians miss about business, and how pharmacy owners can build real stability without losing the heart of patient care. - - - - -  Dr. Lisa Faast, PharmD is a pharmacist with over two dec...

What if healthcare practitioners could serve people more freely while preserving patient choice? In this episode of Peptides and Longevity , Michael Blake, founder of Forgotten Formula, explains Private Membership Associations (PMAs), how member-based models function, and why some clinicians are exploring constitutional frameworks to support integrative, root-cause care. - - - - -  Michael Blake i...

Healing often stalls when care relies on guesswork instead of clarity. In this episode of Peptides and Longevity , Debi Bryk of MaxGen Labs explains how genetic testing provides a lifelong blueprint for personalized nutrition, lifestyle, and supplementation, helping practitioners and individuals move from trial and error to targeted healing. - - - - -  Debi Bryk, NC, BCHN, is a board-certified hol...

He was preparing to lose his bladder after a cancer diagnosis… until his second surgery revealed something no one expected. In this episode of Peptides and Longevity , Jon Vengochea shares how personalized, multi-system care alongside conventional treatment transformed his strength, outlook, and recovery journey. - - - - -  Jon Vengochea is a patient at Holtorf Medical Group who shares his persona...

In this episode of Peptides and Longevity , Michael McNeal sits down with Melanie Murphy Richter to break down how the ProLon 5-Day Fasting Mimicking Diet is designed to keep you just below key nutrient-sensing pathways so you can access autophagy, support gut balance, and reduce cravings while still eating real food. Melanie Murphy Richter, MS, RDN, is a registered dietitian nutritionist with a b...

Most skincare promises repair, but this goes far beyond that. In this episode of Peptides and Longevity , Debbi Barber, founder of Vitali Skincare, shares how copper peptides remodel damaged skin, improve texture and tone, and support healing after procedures through a discovery that transformed her own skin. Debbi Barber is the founder, creator, and CEO of Vitali Skincare, a peptide-based skincar...

Chronic illness doesn’t begin with a diagnosis. It begins with a story. In this episode of Peptides and Longevity , Michael Blake from Forgotten Formula explains how birth trauma, microbiome disruption, toxic exposure, infections, and unresolved trauma accumulate over a lifetime to drive autoimmunity, cancer, and metabolic breakdown. Michael Blake is the founder of Forgotten Formula and a leading...

Healing breaks down when the cell runs out of energy. In this episode of Peptides and Longevity, Dr. Drew Kidder explains why mitochondria drive peptide effectiveness, regeneration, and immune balance, and why real healing must begin at the cellular level. Dr. Drew Kidder is a clinical educator with CellCore Biosciences, where his work focuses on mitochondrial health, detoxification, and cellular...

Aging isn’t just about getting older. It’s about what’s quietly breaking down underneath the surface. In this episode of Peptides and Longevity , Dr. Jeffrey Gladden explains how nervous system regulation, biological aging hallmarks, environment, and regenerative sequencing determine whether aging accelerates or becomes reversible. Dr. Jeffrey Gladden is a former interventional cardiologist and th...

You can look healthy and still feel broken inside. In this episode of Peptides and Longevity , Dr. Miles Nichols joins us to explain why trauma, chronic stress, and environmental illness reshape the brain and nervous system. Tune in to find out how advanced diagnostics, breathwork, and phased healing restore resilience and function. Dr. Miles Nichols is a physician at Medicine With Heart Clinic, w...

Perimenopause can feel like your body and emotions have suddenly turned against you. In this episode of Peptides and Longevity , Dr. Jen Pfleghaar explains why progesterone declines first, why estrogen becomes erratic, and how stress, toxins, and insulin resistance can drive anxiety, weight gain, libido changes, and skin issues years before menopause. Jen Pfleghaar, DO, ABOIM Website: pflegmed.com...

Did you know that most supplements never even make it into your cells? In this episode of Peptides and Longevity , Dr. Jeffrey Gross joins us to explain how plant-derived exosomes act as nature’s delivery system, dramatically improving how nutrients reach and support cellular function. Dr. Jeffrey Gross is a spinal neurosurgeon and regenerative medicine specialist with a background in molecular bi...

Trauma doesn’t stay in the past. It changes how your brain and immune system respond. In this episode of Peptides and Longevity , Dr. Keesha Ewers joins us to discuss the different kinds of trauma and how perceived stress can mirror brain changes in PTSD. We also dive into why healing requires shifting the patterns of your nervous system. Dr. Keesha Ewers is a board-certified functional and Ayurve...

Most supplements fail not because they’re useless, but because they’re poorly made, underdosed, or mislabeled.  In this episode of Peptides and Longevity , Dr. Kent Holtorf speaks with Don Wiencek about private-label supplements, quality control, FDA pitfalls, and how doctors can create effective, ethical formulations their patients can trust. Don Wiencek is the founder and owner of Tru Body Welln...

Most people reach for another coffee when their brain is tired—but what if the real issue is how your brain makes and spends energy? In this episode of Peptides and Longevity , Dr. Gregory Kelly joins us to break down what nootropics are, how caffeine impacts focus and mood, and why mitochondrial health and chronobiology matter for sustainable brain performance. Dr. Gregory Kelly is a naturopathic...

What if your concussion wasn’t just about the hit to your head, but everything that was already simmering in your body? In this episode of Peptides and Longevity, neurosurgeon and functional medicine practitioner Dr. Chad Prusmack joins us to unpack precision medicine, environmental subconcussion, and why toxins, infections, autonomic imbalance, and data-driven rehab can make or break brain recove...

What if your iron wasn’t just high but actively damaging your cells? In this episode of Peptides and Longevity , Bob Miller joins us to explore a little-known process called ferroptosis: a kind of ‘iron overload gone wrong’ that may help explain why some people get stuck in chronic illness. Bob breaks down how everyday exposures, stress, and hidden genetic patterns can overwhelm the body, and shar...

PRP: miracle cure or medical myth? Here’s the real story. In this episode of Peptides and Longevity , Dr. Jeffrey Piccirillo reveals why some platelet-rich plasma treatments disappoint while others spark remarkable repair. He also breaks down the small tweaks that can turn an average treatment into a regenerative breakthrough. If you’ve ever wondered why this therapy seems magical for some and use...

The secret to healthier aging might be hiding in your chromosomes. In this episode of Peptides and Longevity , Eric McDonald of T.A. Sciences joins us to unpack how people are using their supplements to help preserve telomere length, support immune function, and promote healthier aging. ---- Eric McDonald brings almost four decades of experience in biology, pharmaceuticals, and regenerative medici...

Reversing autoimmunity isn’t about chasing perfect lab numbers. It’s about teaching your immune system how to find balance again. In this episode of Peptides and Longevity , Elizabeth Tringali joins us to reveal how small, strategic steps like the right peptides, detox support, and food choices can quiet flares, rebuild energy, and help you feel like yourself again. ---- Elizabeth Tringali is a Bo...

In this episode of Peptides & Longevity, Dr. Kent Holtorf speaks with Dr. Sanjeev Goel, a Toronto-based biohacker and longevity expert. They explore how psychedelics, peptides, and data-driven therapies are transforming health, performance, and aging—revealing what’s next in the science of self-optimization. Born in Montreal and now based in Toronto, Dr. Goel’s journey has been far from conven...

Reignite your libido from the inside out—no shame, no guesswork. In this episode of Peptides and Longevity , Dr. Valerie Phillips joins us to uncover what really drives desire. She shares how rebalancing your hormones, optimizing sleep, calming stress, and even healing your gut and pelvic floor can reignite libido, naming certain peptides may be the missing piece to bringing your passion back. Los...