Neurology English Podcast

What you will learn This conversation introduces common abnormal gait patterns and their associated neurological diseases. Key words Sensory ataxia. Cerebellar ataxia. Spastic gait. Scissoring gait. Parkinsonian gait. Steppage gait. Intermittent claudication. Waddling gait. Source Clinical neurological examination and standard clinical practice. Note This episode is for educational purposes only....

What you will learn This conversation introduces how to perform a basic reflex examination, including deep tendon reflexes, the Jendrassik maneuver, and the Babinski reflex. Key words Jaw jerk reflex. Biceps reflex. Patellar tendon reflex. Jendrassik maneuver. Babinski reflex. Source Clinical neurological examination and standard clinical practice. Note This episode is for educational purposes onl...

What you will learn This conversation introduces how to askabout numbness and how to perform a basic sensory examination. Key words Numbness. Anesthesia. Dysesthesia. Pain andtemperature sensation. Joint position sense. Vibration sense. Source Clinical neurological examination andstandard clinical practice. Note This episode is for educational purposesonly. This is a practice conversation, not a r...

What you will learn This conversation practices manual muscle testing using simple and clear English commands for neurological examination. Key words Neck flexors, Neck extensors, Deltoid, Biceps brachii, Triceps brachii, Wrist extensors, Wrist flexors, Pinch, Abductor pollicis brevis, First dorsal interosseous, Abductor digiti minimi, Flexor digitorum profundus, Iliopsoas, Rectus femoris, Hamstri...

What you will learn This conversation introduces a step-by-step cranial nerve examination and helps you practice simple and practical English commands used in neurological exams. Key words Olfactory nerve. Optic nerve. Oculomotor nerve. Trochlear nerve. Trigeminal nerve. Abducens nerve. Facial nerve. Vestibulocochlear nerve. Glossopharyngeal nerve. Vagus nerve. Accessory nerve. Hypoglossal nerve....

What you will learn This episode reviews a multicenter retrospective study on cancer-associated stroke and explains why post-treatment plasma D-dimer levels, rather than pre-treatment levels, are independently associated with poor short-term outcomes and mortality.   Key words Cancer-associated stroke. Hypercoagulability. Recurrent. Cumulative. Mortality rate. Adjusted odds ratio. Anticoagulation...

What you will learn This episode reviews a multicentre retrospective study of corticosteroidtreatment in CIDP and explains that daily prednisolone, pulsed dexamethasone,and pulsed intravenous methylprednisolone showed broadly similar efficacy andsafety outcomes. Key words Pulsed dexamethasone. Pulsed intravenous methylprednisolone. Remission rates. Cumulative steroid dose. Responder. Source van Li...

What you will learn This episode reviews a multicentre UK study on very high dose immunoglobulin treatment in CIDP and explains why dose escalation may not always be the best option in patients with a poor response.   Key words Pre-treatment disability. Maximal improvement. Thromboembolic complications. Suboptimal response. dose escalation.  Source Very High Dose Immunoglobulin Treatment for Chron...

What you will learn This episode reviews a multicenter study on chronic inflammatory demyelinating polyradiculoneuropathy, or CIDP, and explains how early treatment may be a key modifiable factor in reducing long-term disability. Key words determinants, therapeutic factors, long-term disability, univariate and multivariate linear regression analyses, modifiable factor Source Determinants of long-t...

What you will learn A short review of a serious case report involving lecanemab, t-PA, and multiple cerebral hemorrhages after acute ischemic stroke. Key words cerebral hemorrhage, t-PA, homozygous, gaze preference, administer, intraparenchymal, cerebral amyloid angiopathy Source Multiple Cerebral Hemorrhages in a Patient Receiving Lecanemab and Treated with t-PA for Stroke. N Engl J Med. 2023;388...

What you will learn A short review of the TRAILBLAZER-ALZ 2 trial and how donanemab showed clinical benefit in early symptomatic Alzheimer’s disease. Key words early symptomatic Alzheimer’s disease iADRS least-squares mean change CDR-SB amyloid plaque ARIA Short summary This episode reviews the TRAILBLAZER-ALZ 2 trial, published in JAMA in 2023. Donanemab slowed cognitive and functional decline in...

What you will learn A short review of a key paper in neurology, explained in simple English. Key words monoclonal antibody protofibril cognitive decline CDR-SB ADAS-Cog14 adjusted mean change adverse events Short summary Lecanemab slowed cognitive and functional decline in early Alzheimer’s disease over 18 months. Clinical outcomes such as CDR-SB and ADAS-Cog14 also favored lecanemab, although adv...