MedInsights Unleashed

Breast cancer care continues to evolve rapidly as new research helps clinicians personalize treatment and improve patient outcomes. In this episode of MedInsights Unleashed, Dr. Christine Simmons MD , Associate Professor in the Faculty of Medicine at the University of British Columbia (UBC) and specialist in breast cancer and sarcoma, reviews the most important breast cancer studies presented at A...

Many patients believe that once a prescription is written, receiving treatment is a straightforward process. In reality, prior authorizations, insurance requirements, specialty pharmacy restrictions, and affordability challenges can create significant barriers to accessing care. In this episode of MedInsights Unleashed, Patrick R. Coyle MBA, joins John Collins to discuss the complexities of health...

The RASolute 302 trial represents a breakthrough in pancreatic cancer treatment, successfully doubling patient survival compared with standard care. In this episode of MedInsights Unleashed, Prof. Philip Philip, Professor of Medical Oncology, Wayne State University School of Medicine and Henry Ford Cancer Institute, discusses how targeting KRAS mutations may change the treatment landscape for panc...

In this episode of MedInsights Unleashed , John Collins speaks with Professor Gregory Randolph MD, FACS, FACE, Bertucci Chair in Thyroid Surgical Oncology at Harvard Medical School, about the evolving role of neoadjuvant therapy in advanced thyroid cancer. The discussion explores the challenges of locally invasive thyroid cancer and how neoadjuvant lenvatinib prior to surgery may help improve surg...

In this episode of MedInsights Unleashed , John Collins speaks with Devin Hinchcliffe about one of the most important life-saving interventions in medicine and emergency care — CPR. The discussion explores CPR fundamentals, CPR-102 updates, AED use, DNR considerations, and why rapid intervention by both healthcare professionals and members of the community can significantly improve outcomes during...

In this episode of MedInsights Unleashed, Wayne Paterson, Vice Chairman and CEO of Anteris Technologies, joins us to discuss one of the fastest evolving areas in structural heart disease — whether the future of valve replacement lies not only in replacing diseased valves, but also in restoring more natural heart flow. The discussion explores aortic stenosis, the evolution of TAVR, and the emerging...

In this episode of MedInsights Unleashed , John Collins speaks with Patrick Coyle, MBA, about the often-overlooked journey patients face after receiving a prescription. The conversation explores the complex system behind drug access—including insurance coverage, copays, prior authorizations, and the role of pharmacies. Patrick provides insight into how financial and operational factors influence w...

In this episode of MedInsights Unleashed , Professor Markus Peck-Radosavljević, MD, MBA—Professor of Medicine and Chairman of the Department of Internal Medicine & Gastroenterology at Klinikum Klagenfurt, Austria— discusses evolving treatment strategies in hepatocellular carcinoma (HCC). The conversation explores the changing role of transarterial chemoembolization (TACE) in intermediate-stage...

In this episode of MedInsights Unleashed , the discussion focuses on advanced chronic spine pain and when surgery becomes part of the care pathway. Dr. Rohan R. Lall, neurosurgeon at M Health Fairview University of Minnesota Medical Center, shares clinical perspective on evolving surgical approaches for patients with severe degeneration, instability, and chronic nerve-related pain. The conversatio...

Dr. Lori Wirth, MD—Elizabeth and Michael Ruane Chair of Endocrine Oncology; Medical Director of the Massachusetts General Hospital Center for Head and Neck Cancers; and Professor of Medicine at Harvard Medical School—joins MedInsights Unleashed to discuss modern thyroid cancer care. She explores differentiated, medullary, and anaplastic disease; advances in diagnosis and treatment; the role of gen...

In this MedInsights Unleashed episode, we explore an emerging treatment for chronic degenerative disc disease called Hydrafil. Our guests are Bill Niland , CEO of ReGelTec Inc., and Dr. Anthony Lowman, PhD , Professor of Biomedical Engineering and Co-Founder/Chief Medical Officer at ReGelTec. They walk us through the science, creation, and development of this injectable hydrogel technology. Hydraf...

In this episode of  MedInsights Unleashed , Professor Pierre Gholam, MD., FAASLD, AGAF , returns to explore the transformative potential of  GLP1-based therapies  beyond diabetes and obesity. The discussion highlights how these drugs may play a groundbreaking role in **cancer prevention—particularly liver cancer—**by addressing the root causes of  metabolic dysfunction , a growing public health cr...

We’re honored to share a powerful new episode featuring Dr. Pierre Gholam , MD, FAASLD, AGAF—Professor of Medicine at Case Western Reserve University and Director of the Hepatobiliary Multidisciplinary Team at University Hospitals Seidman Cancer Center. With clarity and compassion, Dr. Gholam explores the complex and evolving nature of liver cancer, tracing its historical roots in viral hepatitis...

We are privileged to have Dr. Ari Rosenberg, MD, and Dr. Maha Elsebaie, MD, MSc, from the University of Chicago, join us to discuss groundbreaking research in neoadjuvant head and neck cancer treatment . This episode explores how circulating HPV DNA , measured through a simple blood test , is emerging as a powerful tool to guide therapy decisions , personalize treatment , and potentially reduce th...

Groundbreaking research presented at ASCO with Dr. Elinor Barsh, MD, and Dr. Jacob Keeling, MD, focuses on advances in immunotherapy for CTLA-4 resistant melanoma. This episode highlights the importance of recent progress, including the Phase I study of the antibody–drug conjugate ozuriftamab vedotin. Dr. Barsh and Dr. Keeling discuss new clinical trial data, evolving treatment pathways, and the s...

Dr. Sharlene Gill, MD, joins the MedInsights Unleashed podcast to discuss the Challenge Study's promising results on exercise in cancer care. Conducted over 17 years, the study revealed that colon cancer patients engaging in structured exercise post-treatment exhibited improved survival rates. The trial involved a comprehensive three-year program incorporating both in-person and virtual components...

In this episode of MedInsights Unleashed, Dr. Ari Goldman, MD, FAAOS, and Lewis Collins, OPA-C, ATC, OTC, from the Northwell Health Orthopedic Trauma and Surgery Team, uncover the facts on knee replacements. The discussion kicks off with a detailed look at knee anatomy and the factors leading to knee replacements, such as arthritis and genetic predispositions. The episode delves into the importanc...

Professor Philip A. Philip, MD, PhD, FRCP, Professor of Medical Oncology at Wayne State University School of Medicine and the Henry Ford Cancer Institute, returns to the MedInsights Unleashed podcast discusses the intricate topic of neuroendocrine tumors(NETs), including their rarity, the non-aggressive nature of many cases, and their potential functional characteristics. Prof. Phillip clarifies c...

In this episode of MedInsights Unleashed, Dr. Kriti Dhamija, MD, a second-year resident in the Department of Internal Medicine at Allegheny Health Network, Pittsburgh, Pennsylvania, USA, challenges the misconceptions around palliative care, particularly in pancreatic cancer. She explains why palliative care should begin at diagnosis, not at the end of life, and how early referral can reduce ER vis...

In a recent episode of MedInsights Unleashed, Dr. Danny Rischin, MD, medical oncologist/clinician researcher at the Peter MacCallum Cancer Centre and Professor, Sir Peter MacCallum Department of Oncology, University of Melbourne, discusses the groundbreaking C-POST study focused on cutaneous squamous cell cancer. By utilizing the immunotherapy drug, cemiplimab, the study achieves a 68% reduction i...

In this episode of  MedInsights Unleashed , Professor Philip A. Philip, MD, PhD, FRCP, Professor of Medical Oncology at Wayne State University School of Medicine and the Henry Ford Cancer Institute, shares vital insights into one of the most challenging cancers to detect and treat—pancreatic cancer. He highlights the urgent need for early recognition of symptoms and the growing understanding of ge...

In this hard-hitting episode of MedInsights Unleashed , we tackle the escalating crisis of drug-related medical emergencies with guest speaker Eric Prach, MAS, BPsych—an EMT and police officer on the frontlines. This episode uncovers the harsh realities of fentanyl-laced overdoses, the rise of synthetic additives like Xylazine, and the increasing concern over Kratom use among young individuals. Er...

Episode Summary: This is the second episode in our series on colorectal cancer. In this episode of MedInsights Unleashed , we sit down with Prof. Paulo Hoff, MD, PhD, from the University of São Paulo, Brazil, to discuss the latest developments in colorectal cancer treatment. With cases increasing, especially among younger adults, the conversation underscores the importance of early screening and d...

Osteoporosis is often viewed as a women’s disease, but in this episode of MedInsights Unleashed , Dr. Tom Forfa, MBBS, reveals why men are also at serious risk. A retired physician and osteoporosis educator from Queensland, Australia, Dr. Forfa shares his personal journey, from multiple fractures to a delayed diagnosis, highlighting the need for early screening and awareness. This episode uncovers...

In this latest episode of MedInsights Unleashed , we are delighted to welcome Dr. Paulo Hoff, MD, PhD, Professor of Clinical Oncology at the Department of Radiology and Oncology, University of São Paulo. Dr. Hoff discusses the rising incidence of colorectal cancer in younger populations, highlighting key risk factors including poor diet, sedentary lifestyle, and obesity. He emphasizes the critical...