LifeSci Talks

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Farrell Healion, Founder and Principal Consultant at OptiTrial, to explore why study design is so often the overlooked "missing link" in clinical development and where real flexibility and patient centricity live. Together, they unpack the gap between what a protocol asks for and how i...

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Stacie Hudgens, Chief Scientific and Strategy Officer at Clinical Outcome Solutions, to discuss whether the field of clinical outcome assessment has started sacrificing “good for perfect.” Together, they explore the role of regulatory guidance and clinical development timelines, specif...

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Lina Eliasson PhD CPsycho, Founding Partner at Sprout Health Solutions, to discuss how pharma companies of all sizes can build a comprehensive, patient-centric evidence strategy that spans the entire drug development pathway. Together, they examine the growing role of COA and in-study...

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader & COA SME at TransPerfect Life Sciences, is joined by Katja Rudell, VP of Patient-Centered Outcomes at Kielo Research, to take a behind-the-scenes look at the reality of patient-centered instrument development. They discuss diaries and quality of life tools, rare disease challenges, and proxy reporting, as well as the tradeoff...

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Alice Biggane, Outcomes Innovation and Research Lead at Pfizer UK, to discuss how various PRO measures inform and impact reimbursement decisions for HTA driven markets.  Together they unpack what data sources and methods exist for the quantification and understanding of HRQoL for cost-...

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, is joined by Jonathan Norman, Director of Translation and Localization at YPrime, for an in-depth discussion on the realities of eCOA libraries. Together, they explore why “libraries” are more accurately described as asset repositories, the conditions under which reuse can meaningfully accelerate stu...

In this tech-forward episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, welcomes Indira Jain-Figueroa, Product Director at Evinova, for a deep dive into the ever-evolving landscape of eCOA development. Covering everything from cross-platform development, backups, and emulator use to the future role of AI in reporting, this conversation highlights how innovat...

Artificial intelligence is redefining what’s possible across the clinical development lifecycle, but with rapid innovation comes the need for thoughtful oversight. In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Richard “ RJ ” Kedziora, Co-Founder of Estenda Solutions, to explore how AI is transforming clinical research and digital...

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Dr. Kate Williams, Director of Patient-Centred Outcomes Research at Acaster Lloyd, to explore the nuances of gathering and applying qualitative data in rare disease research. From intaking both the patient and caregiver experience using a narrative approach, to qualitatively describing...

In this episode of  LifeSci Talks , Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Elizabeth (Nicki) Bush, Executive Director and Global Head of Endpoint Strategy and COA Measurement at OPEN Health Group to discuss the growing complexity of collecting and interpreting patient data. With insights from the recent FDA workshop around Patient-Focused Drug Development (...

In this episode of LifeSci Talks, TransPerfect’s Global Practice Leader Mark Wade sits down with Dr. Karl McEvoy, VP of eCOA and Patient Technology at YPrime, to discuss the importance of embracing technology in clinical research to reduce the patient burden. The two cover everything from updating legacy instruments to more modern solutions such as using video assessments, to incorporating caregiv...

In this episode of LifeSci Talks, TransPerfect Life Sciences’ Global Practice Leader Mark Wade sits down with Kelly Dumais PhD, Director of eCOA Science at Clario to discuss the significance rater training plays in standardizing the administration and scoring of clinical scales. Aiming to reduce bias and enhance data quality, you’ll hear about potential strategies for better engaging patients and...

In this episode of TransPerfect LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences sits down with John Reites, Co-Founder and CEO of THREAD research to discuss the importance of patient listening and in-study interviews to build better clinical trial endpoints. They delve into the differences between enterprise and point solutions, challenges with standardization, and t...

In this episode of TransPerfect LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences sits down with Tom Willgoss, Patient-Centered Outcomes Research Chapter Lead, UK Site Head for Data Sciences at Roche to discuss the value of understanding and measuring patient experience data throughout the clinical journey. They delve into the significance of patient-centered clinical...

 In this episode of TransPerfect LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Dr Michelle Longmire, CEO of Medable, to discuss her journey from clinical practice to entrepreneurship, driven by a passion for rare disease, and the need for technological innovation in clinical research. The conversation highlights key challenges faced in transitioning...

In the first part of TransPerfect's latest LifeSci Talks episode, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, with guest Dr. Michelle Longmire, CEO of Medable, spoke about how a Stanford doctor transitioned into a career of entrepreneurship, creating a multimillion dollar eClinical company. Continuing the conversation in part two, the pair explore the commercial aspects of e-c...

In this episode of TransPerfect LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences sits down with Andrew Lloyd, Director at Acaster-Lloyd Consulting, to spotlight the burden of clinical research for patients, and their caregiver/family dynamics. From ethical considerations surrounding patient/caregiver consent, to the intricate timing challenges of data collection, the...

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Stacey Higgins, Associate Director, COA & Digital Implementation Team at AbbVie, to cover the intricacies of clinical trial licensing, contract variations among eCOA providers, the importance of sponsor involvement, and the challenges of validated translations. Explore the complexi...

DCTs have picked up significantly in previous years, catalyzed by the pandemic and a move to remote research. With this move comes a host of new challenges, including those surrounding technical interoperability, resistance to adopting new technologies, and the need for flexibility in technology uptake at research sites. With additional considerations to be made, such as ensuring regulatory compli...

Explore how artificial intelligence is rapidly changing the landscape of clinical trials, from discovering new therapies and complex calculations to protocol optimization. Discover how AI can generate study protocols, consent forms, and more, saving time and resources. Join us to unravel the potential of AI in reshaping the future of medical research and clinical trial operations.

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Dr. Florence Mowlem, VP of Science at ObvioHealth, to discuss maximizing patient accessibility in trial design. This includes implementing accommodations for patients with physical and cognitive limitations, and ensuring thoughtful applications of electronic modalities.

In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences sits down with Dr. Elizabeth Bacci, Senior Research Scientist at Evidera., to discuss critical aspects of developing meaningful and relevant Digital Health instruments. The conversation emphasizes the importance of aligning digital health tools with individual patient needs, and prioritizing the patie...

Mark Wade interviews Paul O'Donohoe, Senior Director of Product for eCOA and COA at Medidata. They delve into the challenges and opportunities of adopting decentralized clinical trials (DCTs) and explore topics such as mixed modalities for data capture, patient burden, site-centricity, HTML5-based app wrappers, regulatory advancements during the pandemic, and the importance of flexibility in clini...

Tune in to our chat with Aaron McCormick, Associate Director, eCOA Implementation at Moderna, to unravel the importance of standardized eCOA systems across trials and indications. Explore compliance reporting, document management, and TMF guidelines, and gain invaluable insights for successful trial execution and inspection readiness.

What is implementation science, and how can it revolutionize patient-centered healthcare? Join Dr. Meredith Smith in conversation with Mark Wade as they discuss this systematic approach to bridging the gap between healthcare innovations and routine settings. Explore its potential to improve patient outcomes and reduce therapy wastage, while gaining attention from regulatory authorities.