Get the STUCK Out

Ibogaine has surged in popularity as a topic due to its potential to target addiction, trauma and more. But as is always the case with sensational topics, much of what you hear may be false. In this episode, we sit down with a world expert on the topic to understand what is known about this powerful molecule and what is still to be discovered as well as risks and opportunities. Dr. Deborah C. Mash...

6 Daily Habits to Help Prevent Dementia & Keep Your Brain Sharp | Dr. Austin Perlmutter  Dementia and Alzheimer's disease are on the rise — but science shows your daily habits can significantly lower your risk. In this video, physician and brain health expert Dr. Austin Perlmutter shares 6 science-backed strategies to help prevent dementia, protect memory, and keep your brain sharp at any age. The...

The New Science of Psychedelics for Brain Health 🧠✨ For thousands of years, humans have turned to psychedelic plants and fungi—from psilocybin mushrooms to peyote cactus—for healing, ritual, and transformation. But now, cutting-edge neuroscience is uncovering how these substances may do more than alter consciousness—they may rewire the brain and reduce inflammation in ways that could benefit men...

Is sugar toxic to the brain? From honey to aspartame, here's the sweet science of sugar and sweeteners for brain health. #health #brain #sugar   This podcast is sponsored by Lichen Air. I helped start Lichen Air because air pollution is a top threat to brain health. We build science-backed air purifiers with advanced HEPA-14 filters and large-room capacity for brain wellness. Our industry-leading,...

Creatine may boost brain metabolic and immune systems. This is cutting-edge research worth knowing!  For all the references/articles I cited: https://www.austinperlmutter.com/post/the-neuroscience-of-creatine #creatine #muscle #memory #neuroscience Check out my newsletter! https://www.austinperlmutter.com/newsletter This content is not intended to diagnose, treat, cure, or prevent disease. The inf...

Here's the latest science on brain fog, what may be causing it and the current knowledge about potential therapeutic modalities  Check out my newsletter! https://www.austinperlmutter.com/news2  

Here's the latest science on if we should nap, how we should nap and what we should consider for brain health.  Full article with references: https://www.austinperlmutter.com/post...https://www.austinperlmutter.com/post/napping-good-or-bad-for-your-brain Check out my newsletter!  https://www.austinperlmutter.com/news2 This content is not intended to diagnose, treat, cure, or prevent disease. The i...

Food influences cellular aging. Avoiding certain foods may help protect your brain and body from premature aging. I discuss the science around 3 of these foods.  Full article with references:  https://www.austinperlmutter.com/post... Check out my newsletter!  https://www.austinperlmutter.com/news2 This content is not intended to diagnose, treat, cure, or prevent disease. The information provided b...

Groundbreaking research connects muscle mass to brain health. In this episode, you'll discover how resistance training may help fight dementia and depression, why metabolic health starts with your muscles, and how specific nutrients and supplements can supercharge both body and mind. For my full free guide to this topic + all the studies I cited, along with a guide to top plant and animal based pr...

Chronic inflammation is convincingly linked to higher risk of psychiatric disorders. But how, and what can we do about it? We cover: inflammatory cytokines, the inflammatory hypothesis of depression, key pathways acted on by inflammation in the brain and the role of pharmaceuticals and lifestyle factors in acting on inflammatory pathways related to mental health. Check out the below blog for all t...

How Does Coffee Impact Your Brain? In this video we explore Brain Health, Alzheimer's Prevention, Mental Health, Mechanism, Dosing and Metabolism Check out the below blog for all the references https://www.austinperlmutter.com/post/what-coffee-does-to-your-brain Check out my newsletter! https://www.austinperlmutter.com/newsletter This content is not intended to diagnose, treat, cure, or prevent di...

In this episode, I discuss the four major types of brain cells, including neurons, microglia, astrocytes and oligodendrocytes, what they do and their role in brain health. I then discuss the research on what we can do to help optimize their function. Get my Free Guide: 11 Science-Backed Steps to Help Boost Memory and Prevent Dementia: https://www.austinperlmutter.com/memoryguide Check out my free...

Creatine May Have Brain and Muscle Benefits: Initially popular among athletes for muscle growth and performance, creatine is now recognized for its potential positive effects on brain function. Naturally occurring in the body, especially in muscles, supplementation can significantly boost its levels. Enhancing Brain Function: Studies suggest that creatine supplementation increases brain creatine l...

Alcohol use has been part of human culture for millennia. But modern research has revealed that ethanol may be a major risk for our brain health, and a potential brain booster. So, which is it? #alcohol #health #brainhealth #neuroscience Here's my full take: https://www.austinperlmutter.com/post/what-does-alcohol-really-do-to-your-brain Want more brain science?  Subcribe to my newsletter! https://...

We've all heard about exercise for preventing cardiovascular disease and weight gain. But where is the conversation about lifestyle modification to prevent conditions like depression? We have more than enough data to recommend diet, exercise, sleep and mindful interventions, and given the incredible damage to our health posed by conditions like depression, I think it's high time we give preventive...

There are thousands of molecules found in plants that are now known to impact everything from inflammation to the gut microbiome. They're called "polyphenols" and they may help explain why eating more whole plant foods is linked to better overall and brain health. For more, check out my website at Austinperlmutter.com

All of us hear about "superfoods" and amazing vitamins and minerals that will fix everything from poor memory to our mood. But what does the science say about the traits of the top foods for brain health? Here are some top takeaways: • Food turns into the building blocks for our brains, so eating more high-quality foods may be a good recipe for a higher-quality brain • Foods that are rich in polyp...

Get the Stuck Out Shorts   Your brain uses more energy (by weight) than any other organ in the body. Your 86 billion neurons each contain up to a million mitochondria, responsible for generating power to keep your thoughts and consciousness running. When things go wrong, we may be at higher risk for brain diseases. So how does this complex system work, and what might we be able to do to improve it...

A recent study finds that erythritol may be bad for brain health. But how does sugar impact the brain overall, and what does the research say about sugar alternatives? Should we eat more honey? How does the microbiome factor in? For a nuanced conversation specific to the recent erythritol study, check out my blog at austinperlmutter.com/blog 

Depression is a worldwide issue experienced by hundreds of millions. For years, the main theory of what was going wrong in the brain focused on the neurotransmitter serotonin. This theory is called the serotonin hypothesis, and it's based on a number of data points. But recently, researchers have questioned whether serotonin plays a central or even a major role in depression at all. In this episod...

In this episode of Get the STUCK Out, Dr. Will Bulsiewicz (Dr. B) explores the role of gut health on diseases like autoimmunity, allergy cancer and inflammation. We talk about the best diets to support gut health, and how the microbiome shapes us. We compare different diets (e.g keto and more plant based) for their effects on health and talk actionable strategies to improve gut health.  You can fi...

How does nature influence our brain function? In this episode we'll review the science connecting exposure to nature, or "vitamin N" with improvements in general as well as brain health, and the pathways that might help explain some of these findings. We'll cover the connection between nature and stress, the sympathetic nervous system and the immune system, and how our lives spent away from nature...

Deep dive episode! With millions reporting symptoms of brain fog, depression, anxiety and trouble focusing alongside infection with COVID-19, many want to know: how is the virus influencing the brain? In this video, we'll explore: Historical context for microbes influencing brain function. Methods by which SARS-CoV-2 could enter the brain. Evidence for infection in the brain. Alternative explanati...

Neuroplasticity is the brain's ability to change itself over the course of our lives. Impairments in neuroplasticity have been linked to depression, and many antidepressive therapies may actually work in part by boosting neuroplasticity. In this podcast we'll cover: -How neuroplasticity changes over the lifespan -The connection between impaired neuroplasticity and depression psychology -How neurop...

Trauma is certainly a popular topic of conversation these days. But few in this space share the level of expertise offered by Dr. James. S. Gordon. Dr. Gordon has been helping people around the world to understand and heal from their trauma for decades. Listen as he shares his years of clinical and research experience on how trauma manifests in the brain, body and psychological state, and what to...