1PM

First Principles of Medicine

Health EN ↓ 74 episodes

🌐 1PM.WIKI 🌐🔍 🎲 Welcome to 1PM, in this series we will be breaking down complex medical topics into their First Principles.😟 When the stress is on, and you’ve just been asked a tough question you don’t know the answer to, we feel you’ll be able to fall back on these principles to formulate a decent answer and reason your way out of trouble.

Author

1PM

Category

Health

Podcast website

1pm.wiki

Latest episode

Jun 13, 2026

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Episodes

#39 Abnormal Uterine Bleeding (Part I) 13.06.2026

First Principles of Abnormal Uterine Bleeding (AUB) Think it's "just PMS"? Think again! In Part I of our AUB series, we dive into what counts as normal menstrual bleeding, when bleeding becomes abnormal, and the common causes behind it. Join us as we unpack the basics of Abnormal Uterine Bleeding and turn a confusing topic into something clear, practical, and surprisingly fascinating...

#38B - Seizures...in 5 minutes! 08.11.2025

The First Principles of Seizures (Summary): Join us for the summary version of our seizures episode. ⁠1PM Notion: Seizures⁠ === Other Links === 1PM Website Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes. Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠https://www.instagram.com/firstprinciple...

#38A - Seizures: When electricity becomes pathology! 08.11.2025

The First Principles of Seizure: Join us as we explore the electrifying world of seizures and epilepsy. We hope this episode will provide you with a clearer framework to describe, investigate, diagnose, and manage seizures from a patient’s first seizure to the emergency of status epilepticus. 1PM Notion: Seizures === Other Links === 1PM Website Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠1pm.wik...

#37B - The Limping Child... in 7 minutes! 02.09.2025

The First Principles of The Limping Child Summary version of "The Limping Child," best used as brief revision of key concepts explored in the original episode. === Other Links === Check out our notion document on this topic: https://www.notion.so/1pm/37-The-Limping-Child-261ef1d0b55f80bf84e1eb1b3a86b736 Check out our website 1pm .wiki for the Notion document, free Anki flashcards, and po...

#37A - The Limping Child 01.09.2025

The First Principles of The Limping Child In this episode we seek to break down a common paediatric presentation into the essentials, primarily covering a systematic approach to differentiating the causative pathologies. Join us as we limp towards a diagnosis. === Other Links === Check out our notion document on this topic: https://www.notion.so/1pm/37-The-Limping-Child-261ef1d0b55f80bf84e1eb1b3a8...

#36B - Osteoporosis... in 4 minutes! 11.08.2025

The First Principles of osteoporosis: Join us for the summary version of this episode for a quick run down on the presentation, diagnosis and management of osteoporosis. === Other Links === 1PM Website https://1pm.notion.site/36-Osteoporosis-24cef1d0b55f8063ba30cc625d2c8122?source=copy_link Check out our new website 1pm .wiki for the Notion document, free Anki flashcards, and podcast episodes. Ins...

#36A - Osteoporosis: Falls, Fractures and Frailty. 11.08.2025

The First Principles of osteoporosis: Join us as we discuss the pathophysiology, diagnosis and management of osteoporosis, a common condition which you will encounter throughout your medical career. === Other Links === 1PM Website https://1pm.notion.site/36-Osteoporosis-24cef1d0b55f8063ba30cc625d2c8122?source=copy_link Check out our new website 1pm .wiki for the Notion document, free Anki flashcar...

#35B - Septic Arthritis & Gout...in 8 minutes! 03.07.2025

The First Principles of acute joint pain with a focus on septic arthritis and gout. Join us for the summary version of this episode for a quick run down on the presentation, diagnosis and management of septic arthritis and gout. === Other Links === 1PM Website https://1pm.notion.site/35-Septic-Arthritis-Gout-24cef1d0b55f803a903ac17c31e94566?source=copy_link Check out our new website 1pm.wiki for t...

#35A - Red, Hot & Swollen: Septic Arthritis & Gout 03.07.2025

The First Principles of acute joint pain with a focus on septic arthritis & gout. Join us as we discuss an approach to acute joint pain and tackle the key principles of septic arthritis and gout. We hope this episode will provide you a framework of assessing patients with acute joint pain and assist you with the diagnosis and management of septic arthritis and gout. === Other Links === 1PM Web...

#34B - Rash...in 9 minutes! 16.06.2025

The First Principles of Rash (Summary): Join us for the summary version of our rash episode for a quick run down on describing and diagnosing rashes. ⁠1PM Notion: Rash⁠ === Other Links === 1PM Website Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes. Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠...

#34A - Rash: Not just skin deep! 16.06.2025

The First Principles of Rash: Join us as we explore the challenging world of describing and diagnosing rashes. We hope this episode will grow on you as we delve into how to describe a rash and present some rash vignettes to help you better understand and remember the clinical features of both common and serious rashes. We’re joined by Dr Matthew Ghodsian, a dermatology registrar, who shares valuab...

#33B - Inflammatory Bowel Disease...in 5 minutes! 25.05.2025

The First Principles of Inflammatory Bowel Disease (Summary): Join us for the summary version of our IBD episode for a quick run down on the details of pathophysiology to clinical features to diagnosis and management of IBD. ⁠⁠ 1PM Notion: Inflammatory Bowel Disease === Other Links === 1PM Website Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion...

#33A - Inflammatory Bowel Disease: A bad gut feeling 25.05.2025

The First Principles of Inflammatory Bowel Disease: Join us as we tackle the challenging world of identifying, diagnosing and managing IBD, from the GP to ED setting. This episode focuses on how the pathophysiology of immune dysregulation in the gut can be used to remember the clinical signs and symptoms associated with both types of IBD. This episode features repeat presenter Josh (now junior doc...

#32B - Hypokalaemia...in 3 minutes! 05.05.2025

The First Principles of Hypokalaemia (Summary): Join us for the summary version of our hypokalaemia episode for a quick run down on the details of aetiology to management of hypokalaemia. ⁠⁠1PM Notion: Hypokalaemia⁠ === Other Links === 1PM Website Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and po...

#32A - Hypokalaemia: When you’re not oK+ 05.05.2025

The First Principles of Hypokalaemia: Join us as some fresh new voices present everything from the aetiology to the management of hypokalaemia. This episode focuses on how the basic physiology of action potentials can be used to remember the clinical signs and symptoms associated with hypokalaemia. This is the first of many episodes to come that is being led by our new medical student presenters,...

#31B - Acute Otitis Media...in 6 minutes! 06.04.2025

The First Principles of Acute Otitis Media Summary: Join us as we summarise the key principles and takeaways about diagnosis and management of AOM. 1PM Notion: Acute Otitis Media === Other Links === Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠1pm.wiki⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes. Check out our Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠...

#31A - Acute Otitis Media: Hear we go again! 06.04.2025

The First Principles of Acute Otitis Media: Join us as we uncover the principles that underly what is such a common GP presentation that affects children worldwide! We cover everything from the anatomical basis to the specific management guidelines. Hear us out? 1PM Notion: Acute Otitis Media === Other Links === Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠1pm.wiki⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠...

#30B - Shock...in 5 minutes! 15.02.2025

The First Principles of Shock (Summary): a 5 minute summary covering the causes, symptoms, types, and management of shock. ⁠1PM Notion: Shock⁠ === Other Links === Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠1pm.wiki⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes. Check out our Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠https://www.instagram.com/fi...

#30A - Shock! When oxygen delivery begins to stop 15.02.2025

The First Principles of Shock: Join us as we break down the essentials, covering everything from the causes and symptoms, to the latest management strategies. We go through all of the shocking details as well as a case example of a patient in shock, and how to manage it. 1PM Notion: Shock === Other Links === Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠1pm.wiki⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠...

#29B - Pneumonia...OSCE-style summary in 7 minutes! 26.11.2024

The First Principles of Pneumonia: Join us as we break down the essentials, covering everything from the causes and symptoms to the latest management strategies. Whether it's community-acquired, hospital-acquired, or the dreaded atypical pathogens, we’ve got you covered with all you need to know. Does choking on steak causing pneumonia? === Other Links === Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠...

#29A - Pneumonia: Did you eat any steak? 13.11.2024

The First Principles of Pneumonia: Join us as we break down the essentials, covering everything from the causes and symptoms to the latest management strategies. Whether it's community-acquired, hospital-acquired, or the dreaded atypical pathogens, we’ve got you covered with all you need to know. Does choking on steak causing pneumonia? === Other Links === Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠...

#28B - PPH: OSCE-style summary 08.11.2024

The First Principles of PPH: Join us as we dive into the 4 T's – Tone, Trauma, Tissue, and Thrombin – the key culprits behind excessive bleeding. From uterine atony to clotting issues, we’ll walk you through each cause and the life-saving interventions you need to know in managing PPH effectively. === Other Links === Check out our new website ⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠...

#28A - PPH: Push! Push! Harder! 05.11.2024

The First Principles of PPH: Join us as we dive into the 4 T's – Tone, Trauma, Tissue, and Thrombin – the key culprits behind excessive bleeding. From uterine atony to clotting issues, we’ll walk you through each cause and the life-saving interventions you need to know in managing PPH effectively. === Other Links === Check out our new website  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠...

#27B - Vertigo: OSCE-style summary 09.10.2024

The First Principles of Vertigo: Feeling dizzy? Or did you just get hit in the ear? Join us for a spin on the world of vertigo: whether it's crystals in your ears or something more sinister, we've got you covered with tips to help you stay upright. === Other Links === Check out our new website  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ , free Anki flash...

#27A - Vertigo: Did you get hit in the ear? 05.10.2024

The First Principles of Vertigo: Feeling dizzy? Or did you just get hit in the ear? Join us for a spin on the world of vertigo: whether it's crystals in your ears or something more sinister, we've got you covered with tips to help you stay upright. === Other Links === Check out our new website  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ , free Anki flashcard...

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