Fireside Chats on Endocrinology and Metabolism in the Mantzoros lab

Current and emergent incretin-based therapies (such as GLP-1 and GIP receptor agonists) have transformed obesity treatment by producing unprecedented weight loss. But these benefits come with complexity: significant lean mass loss, raising concerns about metabolic stability, muscle health, and long-term outcomes.    In this episode, we briefly revisit the clinical approach to weight-loss medicatio...

Obesity is described by many as the epidemic of the 21st century. Currently, limited and suboptimal drugs are available to the clinician's therapeutic armamentarium. However, novel agents and combination schemes, mainly with Incretin Analogs, seem to be revolutionizing the way we will soon be treating overweight and obesity. In this podcast, we discuss notable drug advancements and concepts of nov...

Este episodio es la traducción en español de nuestra conversación con el Dr. Christos Mantzoros, profesor y endocrinólogo de la Facultad de Medicina de Harvard, sobre el cambio de la terminología de Hígado Graso No Alcohólico (NAFLD por sus siglas en íngles) hacia la Enfermedad Hepática Esteatósica Asociada a Disfunción Metabólica (MASLD). Además hablaremos de la importancia de esta nueva nomencla...

In this episode, Dr. Christos Mantzoros, Professor and Endocrinologist at Harvard Medical School and the editor-in-chief of the Journal Metabolism: Clinical and Experimental, will guide the discussion about the ongoing journey towards refining the NAFLD terminology to Steatotic Liver Disease (SLD) and will shed light to the significance of the recent nomenclature change.  The consensus to shift to...

La obesidad es la epidemia del siglo XXI, pero ¿qué es y por qué la desarrollamos?   ¿Es una enfermedad? ¿Existe la obesidad metabólicamente saludable y la no saludable?   ¡Bienvenido a la serie sobre la obesidad! En este primer episodio, presentaremos conceptos críticos sobre cómo desarrollamos la obesidad y por qué es importante.   ¡Estén atentos de nuestros siguientes episodios de obesidad!   L...

Obesity is the global epidemic of the 21st century, but what is it, and why do we develop it?   Is it a disease? Is there metabolically healthy and unhealthy obesity?   Welcome to the obesity series! In this first episode, we will present critically important concepts on how we develop obesity and why it matters.   There is more to come, please stay tuned!   The authors own the copyright to all th...

La enfermedad del hígado graso no alcohólico (NAFLD, por sus siglas en inglés) es una importante epidemia de salud pública estrechamente relacionada con las epidemias de obesidad y síndrome metabólico. Su prevalencia, combinada con los avances recientes de la investigación, requiere que los endocrinólogos y los médicos de atención primaria participen en la identificación y el manejo de las persona...

Nonalcoholic fatty liver disease (NAFLD) is a major public health epidemic closely linked to the epidemics of obesity and the metabolic syndrome. Its prevalence, combined with recent research advances, necessitates that endocrinologists and primary care physicians are involved in identifying and managing persons affected by, or at risk for developing this disease.   Welcome to our episode Fatty Li...

Bienvenidos al primer episodio de nuestro podcast  ¡Estamos muy emocionados de que te unas a nosotros! Gracias por estar acá,   El Mantzoros Lab, ¡Apasionados por la Endocrinología, la Innovación y la Mentoría!

Welcome to the first episode of the Fireside Chats on Endocrinology and Metabolism in the Mantzoros Lab. We are so excited you are joining us! Thank you, The Mantzoros Lab.  Passionate about Endocrinology, Innovation, and Mentoring!       The following music was used for this media project: Music: Total Happy Up And Sunny by Sascha Ende. License (CC BY 4.0):  https://filmmusic.io/standard-license...