Clot, Clot, Who's There?

The COBRRA Trial and the Questions that Remain Clinicians have long relied on indirect comparisons when choosing between direct oral anticoagulants (DOACs) for VTE. The COBRRA trial changed that. Join experts Behnood Bikdeli, Lana Castellucci, and David Jiménez as they discuss: • The landmark COBRRA trial and its implications for VTE treatment • How bleeding risk, adherence, and patient preference...

When a young, otherwise healthy patient presents with an upper extremity DVT, venous thoracic outlet syndrome should be high on the differential—but the diagnosis is often delayed or missed. Join experts JoMarie Monzon, MSN, FNP-BC and Drs. Donna Bahroloomi, Ali Azizzadeh, and Vincent Jongkind as they discuss: Why venous thoracic outlet syndrome is frequently mistaken for musculoskeletal injury Di...

In urgent, high-stakes situations—like major bleeding or emergency surgery—how should clinicians assess coagulation in patients on factor Xa inhibitors? And more importantly, are we focusing on the right signal? Join global experts as they explore: Why traditional assays (PT/aPTT, anti-Xa) often fall short in critical decision-making The role of functional testing in assessing true hemostatic pote...

Surviving a stroke is only the beginning. Preventing the next one is where the real clinical challenge lies—and for patients with non-cardioembolic stroke, the existing toolkit has long fallen short. Join Drs. Geoff Barnes, Mike Sharma, and Valeria Caso as they explore: Stroke subtypes, recurrence risk, and the unique challenges of non-cardioembolic stroke and ESUS Why current treatment options ha...

When it comes to antithrombotic therapy in coronary artery disease, the central question is no longer "What should everyone get?" It's "What's right for this patient?" In this episode, Drs. Heather Johnson, Ty Gluckman, and Davide Cappodano explore the modern balance between managing clotting and bleeding risk in patients on antiplatelets and anticoagulants. From the evolving role of aspirin and P...

In this episode of Clot, Clot, Who's There? Drs. Christian Ruff (USA) and Giulio Francesco Romiti (Italy) chat about long-term anticoagulation management after successful atrial fibrillation ablation. They explore why stroke risk may persist despite rhythm control, examine emerging evidence from the ALONE-AF and OCEAN trials, and consider how patient selection and shared decision-making should inf...

In this episode of Clot Clot Who's There, Aviva Schwartz, Director of Education at Vasculearn Network, speaks with Professor Gregory Lip about key anticoagulation and atrial fibrillation data from 2025 and what lies ahead in 2026. The discussion spans post–AF ablation management, holistic AF care, and emerging factor XI inhibitors shaping the future of thrombosis management. Tune in now and subscr...

Host Dr. Alex Spyropoulos is joined by global experts Drs. James Douketis and Marc Samama for a focused, practical discussion on perioperative anticoagulation management in nonurgent procedures. Together, they clarify: When and how to safely interrupt warfarin and direct oral anticoagulants Why heparin bridging is now rarely needed How procedural bleeding risk and pharmacokinetics inform decision-...

Host Tara Lech is joined by Drs. Scott Woller and Virginia Silvari for a thoughtful conversation on anticoagulation stewardship: what it is, why it matters, and how it can help patients who need antithrombotic therapy. They share examples from their own practice, talk through common challenges, and offer simple steps for improving care across settings. Topics: What makes anticoagulation stewardshi...

Join host Christian Weber, MD (LMU Munich) with vascular biology experts Kimberly Martinod, PhD (University of Rochester) and Konstantin Stark, MD (LMU Munich) as they explore the evolving science of immunothrombosis and thromboinflammation—concepts that rose to prominence during COVID-19 but reach far beyond infectious disease. Learn about: How thrombotic and inflammatory mechanisms impact cardio...

Join JoMarie Monzon, NP (Cedars-Sinai, Vasculearn Network) as she welcomes moderator Dr. Cassra Arbabi and guests Drs. Donald Baril (Cedars-Sinai) and Efthymios (Makis) Avgerinos (Athens Medical Center) for a high-stakes discussion on acute limb ischemia (ALI). Explore U.S. and European approaches to this vascular emergency—from recognition to revascularization—and gain practical, globally informe...

Dr. Bethany Samuelson Bannow is joined by Dr. Erik Klok and Dr. Geoff Barnes for a discussion on the best ways to communicate with your patients about anticoagulation. Anticoagulation therapy is a cornerstone of care for patients, but starting and managing these medications can be overwhelming for patients. In this episode, we'll cover common patient questions, tips for improving adherence, how to...

Join Dr. Jose Joglar, Chair of the 2023 U.S. AFib Guidelines, and Professor Gregory Lip, Chair of the ESC Council on Stroke, as they dive into the latest U.S. and European atrial fibrillation guidelines. From risk scores to rhythm control, they explore common ground, key differences, and the global shift toward holistic, patient-centered care. (Hint: coffee lovers with AFib, rejoice!) Whether you'...

Join host Dr. Kerstin de Wit as she welcomes Drs. Cecilia Becattini and Behnood Bikdeli to unpack one of the most nuanced challenges in thrombosis care: venous thromboembolism (VTE) risk stratification and anticoagulation management. This case-based conversation explores:  How clinicians navigate decisions around continuing, reducing, or stopping anticoagulation Whether formal risk scores or D-dim...

Does sex influence the risk of atrial fibrillation (AF)-related strokes? Is female sex truly an independent risk factor? And what common myths still cloud clinical understanding? In this episode, host Dr. Giulio Francesco Romiti ( internal medicine specialist from Sapienza University of Rome, Italy ) is joined by guests Dr. Geoff Barnes (cardiologist and vascular medicine specialist, University of...

In this inaugural episode of Clot Clot Who's There , global experts Professor Tatjana Potpara (Serbia), and Dr. Annabelle Volgman (USA) join moderator Dr. Panteleimon Papakonstantinou (Ireland) to discuss the rising global prevalence of atrial fibrillation (AF), a leading contributor to strokes and heart failure. They explore regional differences in AF management, evolving guidelines, and the pote...