VJOncology Podcast

In this week’s VJOncology podcast, leading experts share the latest updates in ADCs in HER2-positive and metastatic breast cancer in recognition of Breast Cancer Awareness Month. Charles Geyer, MD, discusses pivotal results from the Phase III DESTINY-Breast05 trial, where trastuzumab deruxtecan (T-DXd) significantly improved invasive disease-free and disease-free survival versus trastuzumab emtans...

In this week’s VJOncology podcast, leading experts share key updates presented at the ESMO 2025 Congress in Berlin, Germany. Sara Tolaney, MD, MPH, highlights the expanding role of ADCs in earlier lines of metastatic breast cancer, presenting data from the DESTINY-Breast09 and ASCENT-03 trials, and discusses results from DESTINY-Breast05, where trastuzumab deruxtecan demonstrated superior outcomes...

In this week’s VJOncology podcast, leading experts share the latest updates in the management of hepatocellular carcinoma (HCC) in recognition of Liver Cancer Awareness Month. Stephen Lam Chan, MD, FRCP, discusses emerging immunotherapy and targeted approaches, including novel TIM3 and TIGIT inhibitors, and findings from the SIERRA study of durvalumab and tremelimumab in advanced HCC. Lorenza Rima...

In this week’s VJOncology podcast, we are joined by brain tumor experts Stephen Bagley, MD, MSCE, University of Pennsylvania, Philadelphia, PA, and Cecile Riviere-Cazaux, PhD, Mayo Clinic, Rochester, MN, as they discuss the latest updates in cerebrospinal fluid (CSF) liquid biopsies in brain tumors. They will comment on the rationale and challenges in CSF liquid biopsies in this space, current res...

In this week’s exclusive VJOncology podcast, we are joined by Javier Martín-Broto, MD, PhD, Fundación Jiménez Díaz University Hospital, Madrid, Spain, who shares expert insights on the evolving role of immunotherapy in sarcoma. He discusses the unique immunosensitivity of alveolar soft part sarcoma, the potential of combining checkpoint inhibitors with anti-angiogenic or anti-CTLA-4 agents, and en...

In this week’s VJOncology podcast, we have the pleasure to bring you key updates in lung cancer at IASLC 2025 World Conference on Lung Cancer (WCLC), which we attended live in Barcelona, Spain. Join experts John Varlotto, MD, Marshall University, Huntington, WV, Alessio Cortellini, MD, Bio-Medico University, Rome, Italy, Ana Baramidze, MD, PhD, Todua Clinic, Tbilisi, Georgia, Nicolas Girard, MD, I...

In this week’s podcast from VJOncology, three leading experts provide insights into the latest advances in precision medicine for head and neck cancer. Luigi Lorini of Humanitas Research Hospital discusses the evolving treatment landscape of immunotherapy in head and neck squamous cell carcinoma. Danny Rischin of the Peter MacCallum Cancer Centre presents findings from a Phase II trial evaluating...

In this week’s VJOncology podcast, we will be joined by Rupert Bartsch, MD, Medical University of Vienna, Vienna, Austria, as he outlines current and emerging strategies for managing HER2-positive metastatic breast cancer after antibody–drug conjugate (ADC) therapy, with a focus on trastuzumab deruxtecan (T-DXd). He discusses the use of tucatinib-based regimens, mechanisms of resistance to agents...

In this week’s installment of the VJOncology podcast, we will examine the cutting-edge applications of artificial intelligence in clinical oncology. This episode presents a curated series of expert insights into AI-driven tools for early detection, diagnostic precision, biomarker development, treatment guidance, and prognostic assessment. Leading clinicians and researchers discuss breast, sarcoma,...

Join leading GI cancer experts J. Randolph Hecht, UCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA, Jasmine Mitchell, UCLA Santa Monica Medical Center, Santa Monica, CA, and Jingran Ji, UCLA Santa Monica Medical Center, Santa Monica, CA, as they share key insights from the most impactful gastrointestinal cancer updates presented at ASCO 2025. In this episode, they discuss pivotal trials i...

In this week's VJOncology podcast, we will be covering highlights from the American Society of Clinical Oncology (ASCO) Annual Meeting 2025 in Chicago, IL. Gain expert insight on exploratory biomarkers, treatment landscape shifts, and practice-changing trials from leading researchers in the field of genitourinary cancers. Join renowned speakers Angela Jia, Tian Zhang, Michael Harrison, Margaret Ga...

In this episode of the VJOncology podcast, we explore the evolving landscape of gynecologic cancer care with expert insights recorded at the 2025 ESMO Gynaecological Cancers Congress in Vienna. Ilana Cass, MD, Dartmouth-Hitchcock Medical Center, Lebanon, NH, discusses new data from the RUBY trial and the impact of dostarlimab in endometrial cancer. Christina Fotopoulou, MD, PhD, Imperial College L...

In this weeks podcast from VJOncology, five leading experts share updates and insights on the evolving landscape of precision medicine in sarcoma. Robin Jones discusses the complexities of implementing precision medicine and presents results from a Phase III trial of catequentinib in advanced leiomyosarcoma. Javier Martín-Broto explores recent advances in immunotherapy and shares findings from Coh...

In this weeks VJOncology podcast, we have the pleasure to bring you key updates in CAR-T and cellular therapies in brain tumors. Gain expert insights on landmark trials, treatment advances, and shifting screening practices from some of the foremost voices in the field. Topics of discussion include a Phase I trial of intracranial B7H3-directed CAR-T cell therapy in patients with recurrent glioblast...

This week’s VJOncology podcast episode highlights four breakthrough studies from ESMO GI 2025 in Barcelona, Spain, featuring expert insights on gastrointestinal cancer advances. Coverage includes the EXPEL PANC study combining BXCL701 with pembrolizumab for pancreatic cancer, SIERRA study safety data on the STRIDE regimen for hepatocellular carcinoma, TALENTACE trial results combining TACE with at...

Join esteemed experts Joao Victor Alessi, Hospital Sírio-Libanês, Sao Paolo, Brazil, and Alessandro Di Federico, Dana-Farber Cancer Institute, Boston, MA, as they discuss the most anticipated updates in lung cancer presented at ASCO 2025, as they comment on ground-breaking trials and provide their insights on the significance of the findings and updates. In this episode, they comment on the potent...

Join our experts as they delve into the latest advancements in breast cancer presented at ASCO 2025, as they comment on highly anticipated trials and gives their perspectives on the significance of the findings and updates. In this episode, Kevin Kalinsky, Emory University Hospital, Atlanta, GA, and Komal Jhaveri, Memorial Sloan Kettering Cancer Center, New York, NY, receive updates on trials pres...

In this weeks VJOncology podcast, we have the pleasure to bring you key updates in gynecological cancer from ASCO 2025, which we attended live in Chicago, IL. Join leading experts as they comment on key trials and provide their insights on the ever-evolving treatment landscape and screening patterns.   Dr Jyoti Mayadev gives an overview of highly anticipated trials at the conference including the...

In this ASCO 2025 edition of VJOncology podcasts, we spotlight five game-changing studies set to reshape cancer care across multiple tumor types. Join our host and a panel of leading oncology experts as they unpack the most impactful data from this year’s American Society of Clinical Oncology Annual Meeting. Discover pivotal insights from the MATTERHORN trial in gastric cancer, explore KRAS G12C-t...

Welcome to another episode of the VJ Oncology Podcast, where we bring you the forefront of cancer research and clinical practice. This week, we focus on the revolutionary field of cell therapy for solid tumors, with particular emphasis on lung cancer and melanoma. Join Dr. Alison Betoff-Warner and Dr. Ben Creelan as they discuss the potential of targets like TILs, TCRs, and CAR-Ts. Learn about the...

In this week’s podcast, we take you through the latest episodes of the VJOncoAlert Journal Club—a collaborative series from VJOncology and OncoAlert that brings together leading oncology experts to discuss the most impactful and practice-changing research in the field. We are joined by Misty Shields, MD, PhD, from the Indiana University Simon Comprehensive Cancer Center in Indianapolis, IN, who di...

Welcome to this week's podcast by VJOncology, where we delve into the latest developments in adjuvant therapy for hepatocellular carcinoma. Join five leading experts as they discuss cutting-edge research and its impact on clinical practices. Stephen Chan, MBBS, MRCP, The Chinese University of Hong Kong, Hong Kong, China, Laura Williams Goff, MD, MSCI, MMHC, Vanderbilt-Ingram Cancer Center, Nashvil...

In this week's VJOncology podcast, we are focusing again on Prostate Cancer Awareness Month, where we have collaborated with experts on liquid biopsies for tracking and predicting treatment outcomes in metastatic castration-resistant prostate cancer. Join Chinmay Jani from the Sylvester Comprehensive Cancer Centre, Xin Gao from Massachusetts General Hospital Cancer Center, Christos Kyriakopoulos f...

In this weeks VJOncology podcast, we explore key update from BTOG 2025 in thoracic oncology. Prof. Sanjay Popat discusses the evolving role of ADCs in lung cancer treatment, focusing on efficacy, toxicity management, and biomarker integration. Prof. Samreen Ahmed examines ADC resistance mechanisms, drawing insights from breast cancer therapy to refine drug development strategies. Prof. Robert Rint...

In this weeks VJOncology podcast, three oncology experts delve into the transformative potential of liquid biopsy in breast cancer treatment. First, Michail Ignatiadis (Jules Bordet Institute, Brussels, Belgium) discusses the clinical applications and challenges of utilizing liquid biopsy in metastatic breast cancer, focusing on the Phase III TREAT ctDNA trial (NCT05512364) and its implications fo...