The Other 80

Healthcare pioneer Rushika Fernandopulle joins us to discuss his new venture Liza and why this is the perfect moment to build new primary care models from the bottom up. Rushika argues that “shareholder value” has usurped the needs of patients in US healthcare, and that fundamental rethinking, not optimizing or tweaking at the edges, is needed. Rushika shares the ‘build principles’ for Liza: Backl...

Does the history of drugs tell us something bigger about the world? That’s what former Wired executive editor and UC Berkeley Senior Impact Fellow Thomas Goetz is betting on with his new podcast Drug Story. He joins Claudia to talk about how big drug breakthroughs have shaped how we live and what it will really take to build health in our society. Thomas and Claudia dive into: Fluoride: The parado...

After spending time in the Obama White House, Kumar Garg came away with a toolset of skills to help drive change, spotlight good ideas and scale them. Now he’s applying those ideas to philanthropy. As the co-founders of Renaissance Philanthropy, Kumar and Tom Kalil have built an organization around a deceptively simple idea: What if philanthropy could help scientists, technologists, and innovators...

Halle Tecco is an investor, entrepreneur, and author of the new book Massively Better Healthcare . In this live conversation, she offers advice for aspiring health tech founders, reflects on why “hustle culture” needs to be kept in check, and makes the case that founders should become anthropologists of the problems they want to solve. Most importantly, she argues that today’s founders need to be...

After moving to the US from Iran at age 17, entrepreneur and inventor Fred Khosravi went on to launch more than 20 companies and earn hundreds of patents. In this conversation, Fred reflects on the power of immigration, freedom, education and what it means to build a life in a new country. He shares how leaving Iran after the revolution shaped his willingness to take risks, his sense of purpose, a...

Patient innovators Liz Salmi and Hugo Campos join The Other 80 to discuss the evolving role of patients in healthcare, using the recent release of ChatGPT Health as a central lens. They delve into how AI is shifting the power dynamic by enabling greater patient agency and creating new expectations for health systems. Drawing on their personal experiences, including Liz's work with OpenNotes and Hu...

Newly-minted Nobel laureate Fred Ramsdell joins Claudia to discuss his groundbreaking work on regulatory T cells, which act as the immune system's natural "brakes." His research aims to "reset" the immune system to cure autoimmune diseases (like rheumatoid arthritis and MS) moving beyond mere symptom management. Fred reflects on his new role as a science advocate, addressing the crisis of public t...

When Mayor Lurie took office, San Francisco was spending nearly $1 Billion a year responding to homelessness, yet the number of people living unsheltered had not budged in years. In this episode, Kunal Modi, the city’s Chief of Health and Human Services, shares how the Lurie administration is tackling the intersecting homelessness, mental health and addiction crises. Rather than layering on new pr...

Not many digital health companies go public. And even fewer do so with a model designed to fix what’s truly broken in U.S. healthcare: episodic, fragmented care that fails to support the behavior change required to manage chronic disease. Omada Health CEO Sean Duffy joins Claudia to discuss the company’s journey from scrappy startup to public company—and his biggest ambition for the future: bendin...

In 2025, New Mexico made history as the first state in the nation to commit to free childcare for all families. Elizabeth Groginsky, who leads this effort, joins Claudia to discuss what Governor Michelle Lujan Grisham has described as a “cradle-to-career education system”—and why investing early pays dividends from school readiness to family economic stability. Claudia and Elizabeth dive into: The...

This week, we close out our three-part series on rethinking drug access and costs with a must-listen encore episode. After detailing the scope of the drug price crisis with Mark Cuban and how we can re-purpose drugs to treat rare illnesses with David Fajgenbaum, we turn to a leader who is actively changing the dynamic: Paul Markovich. Now the CEO of Ascendiun (the parent company of Blue Shield of...

Investor and healthcare disruptor Mark Cuban joins The Other 80 to talk about his online pharmacy, Cost Plus Drugs, that is bringing affordable drugs with transparent markups to American households. Mark lays out his basic formula for taking overhead and complexity out of the US healthcare system by disaggregating huge vertical businesses and disintermediating middlemen. In this episode, Mark Cuba...

When David Fajgenbaum nearly died of Castleman disease for the fifth time, he decided to take fate into his own hands. Using his medical training, he searched for an existing drug that might save his life—and found one. Now his organization, Every Cure, is scaling the same approach to uncover hidden treatments for other diseases with no known cure. David and Claudia discussed:  How Every Cure...

Richmond, California used to be called America’s “Murder Capital”. But when city leaders chose a different path the city’s gun violence problem dramatically declined.  DeVone Boggan and UC Berkeley’s Jason Corburn join Claudia to discuss their new book “Advancing Peace”, which chronicles their efforts to reduce gun violence in Richmond and other cities by focusing on those most likely to pull...

Investor Nancy Brown joins us at Aspen Ideas Health to share her blueprint for impactful investments. Identify public health breakthroughs that deliver measurable cost and quality improvements — then show how they can thrive in the marketplace. You don’t have to look far to see this playbook in action. One of the year’s biggest health exits, Omada Health, is a digital version of the CDC’s Diabetes...

Grey’s Anatomy Executive Producer and physician Dr. Zoanne Clack joins The Other 80 at Aspen Ideas: Health to talk about what public health leaders can learn from Hollywood storytelling. After training as a doctor and working for the CDC, Zoanne followed her childhood dreams and moved to Hollywood. With no job or warm leads, Zoanne set out to use the power of storytelling to drive health change.&n...

AI is going to transform healthcare - but how do we ensure it does so responsibly, equitably and ethically? Google’s former Chief Health Officer, Dr. Karen DeSalvo, says that AI could be public health’s new best friend - if we use it in the right ways. Karen  sits down with Claudia at Aspen Ideas Health to talk about her longtime career as a public health leader and where she sees a role for...

In a time where we need hope and innovation more than ever, we asked 13 health leaders—all guests on this podcast—what they would do to reimagine health. Tune into the episode to hear what they shared (in order of appearance): David Zipper, Senior Fellow, MIT Mobility Initiative  Maya Petersen, Professor of Biostatistics, Epidemiology and Computational Precision Health, UC Berkeley  Kody...

When we think about digital tools and technology, we think of them as moving fast. Katie Drasser, CEO of Rock Health, joins me to discuss what a “slow tech” approach to health innovation could look like. It would ground innovation in participatory design, build community trust and aim for long term impact, not just rapid scaling. We discuss: How she’s working to fix the broken investment cycle for...

On the surface, what the wellness industry is offering feels like an antidote to our fragmented and fast-paced lives. Influencers and companies use words like "mindfulness" or “whole foods” or “self care” to get our stressed out, burnt out buy in. But, somewhere along the line those promises start to morph into luxury services, expensive memberships and supplements you never knew you needed. In he...

Loneliness isn’t just a feeling - it’s a public health crisis. The number of hours we spend with friends is rapidly decreasing, more and more Americans report feeling lonely, and loneliness is linked to bad health outcomes like risk of premature death, heart disease, stroke, depression and anxiety. Kasley Killam, author of  “The Art and Science and Connection”, joins us to talk about why soci...

What if instead of treating illness we also confronted the reasons Americans get sick in the first place? That’s the origin of this podcast and also the four billion dollar question Dr. Bechara Choucair is tackling at Kaiser Permanente as Chief Community Health Officer. He joins Claudia to talk about the organization’s focus on climate change and health, workforce pipelines and addressing unmet so...

The US leads the world in biomedical innovation, with about 40% of patents being filed by US scientists and companies. The FDA plays a critical role in supporting and enabling this innovation pipeline and our guest Dr. Robert Califf was commissioner of the agency not once, but twice under Presidents Obama and Biden. He joins us to talk about what Americans should know about FDA’s critical role and...

Could primary care at home unlock better health and lower costs for American families? Rebekah Gee, a physician and policymaker turned entrepreneur, joins us to talk about the big bet her company Nest Health is making on home-based primary care. It’s a model that makes sense for families and delivers results. In the first year of operations Nest doubled primary care visits, reduced ER visits, and...

Whether it's the civil rights movement, marriage equality or even seatbelt laws, community organizing is how change happens in America. In this encore episode, Dr. Tony Iton shares a masterclass in how social, political and economic power shape health outcomes and how to meaningfully shift those dynamics when it matters most. Tony argues that reinvigorating democracy at the community and local lev...