Beimnet Kassaye

The Journal Club

Science EN ↓ Odcinki: 19

This podcast is structured as a short scientific journal club where I will discuss scientific papers and relate their major findings. Generally, journal clubs have a scientific audience ranging from college science students to university professors. And the communication during the sessions is of scientific jargon that is very niche to the field of study. For this podcast, I try very hard to use everyday language to explain science. It is not going to be easy, but it will get better over time. I am also a science student, so in this podcast, we learn science together!

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Autor

Beimnet Kassaye

Kategoria

Science

Strona podcastu

rss.com

Ostatni odcinek

24 gru 2024

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Odcinki

New brain cells and how they join the old 24.12.2024

In this episode, I cover a paper by Kochan et al., 2024. The title of the paper is "Enhanced mitochondrial fusion during a critical period of synaptic plasticity in adult-born neurons ." Here is the link for the paper https://pubmed.ncbi.nlm.nih.gov/38582081/ Here is the webpage of the Bergami lab: https://bergami-lab.com . You may access other publications and the current focuses of their lab by...

#18 Housekeeping in the schizophrenic brain with Katy Bjornson 10.12.2024

Katy shares one of her graduate school papers on how a cell clean-up mechanism improves cognition and its consequences in schizophrenia. Here is a link to the paper: https://pubmed.ncbi.nlm.nih.gov/39019008/ And here is the Cahill lab https://cahilllab.wiscweb.wisc.edu

#17 The brain where it is not "thinking": regulating the immune response 05.12.2024

In this episode, I cover a paper by Jin et al., 2024. The title of the paper is "A body-brain circuit that regulates body inflammatory responses ." Here is the link for the paper https://pubmed.ncbi.nlm.nih.gov/38692285/ . Here is the webpage of the Kaeser lab: https://www.zukerlab.com . You may access other publications and the current focuses of their lab by following the link.

#16 Dopamine in psychosis and substance use disorder with Loren Peeters 25.11.2024

Loren Peeters shares her graduate paper titled Effects of positive mGlu5 modulation on D2 signaling and nicotine-conditioned place preference: Mechanisms of epigenetic inheritance in a transgenerational model of drug abuse vulnerability in psychosis . Here is the link for the paper https://pubmed.ncbi.nlm.nih.gov/39462877/ . You can follow the full-text links. Here is the webpage of the Brown lab...

#15 Dopamine as we move and pursue 20.11.2024

In this episode, I cover a paper by Cai et al., 2024. The title of the paper is "Dopamine dynamics are dispensable for movement but promote reward responses ." Here is the link for the paper https://www.nature.com/articles/s41586-024-08038-z.epdf?sharing_token=iaTQaNGlwJ3U0t63gRdvoNRgN0jAjWel9jnR3ZoTv0MqwcJmJFCUL7uZ_15TPCZ8espe7y0UtGVKs-OYDW0-m_RyOV3e_4j76PM8ppXJi_A_Epvvz9vVyfGlJxd6RlTQ6xjr5ibCAnz...

# 14 Length of daylight alters potassium channel expression in our serotonin neurons 07.11.2024

In this episode, I cover a paper by Giannoni-Guzman et al., 2020. The title of the paper is "Circadian photoperiod alters TREK-1 channel function and expression in dorsal raphe serotonergic neurons via melatonin receptor 1 signaling ." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/33210730/ . You may access the paper by clicking on the icons under the "Full Text Links" ta...

#13 Length of daylight and positive mood: the serotonin story 10.07.2024

In this episode, I cover a paper by Green et al., 2015. The title of the paper is "Photoperiod Programs Dorsal Raphe Serotonergic Neurons and Affective Behaviors." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/25959961/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Here are the webpages of Dr. McMahon and Dr. Grueter respectively: ht...

#12 Seasonal change in daylight on reward and motivation: the dopamine story 03.07.2024

In this episode, I cover a paper by Jameson et al., 2023. The title of the paper is "Photoperiod Impacts Nucleus Accumbens Dopamine Dynamics." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/36781229/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Here are the webpages of Dr. McMahon and Dr. Grueter respectively: https://www.mcmahonlab....

#11 Could KLOTHO be the long-awaited Alzheimer's drug? 13.06.2024

In this episode, I cover a paper by Zhao et al., 2020. The title of the paper is "Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease . " Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/32964663/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Here is the webpage of Dr. Jun-R...

#10 The Western diet and Alzheimer's disease (Second half with Stedman Stephens) 05.06.2024

In this episode, Stedman and I cover the second half of a paper by Poxleitner et al., 2024. The title of the paper is " Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis. " Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/38745337/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Here are...

#9 The Western diet and Alzheimer's disease (First half with Stedman Stephens) 29.05.2024

In this episode, Stedman and I cover the first half of a paper by Poxleitner et al., 2024. The title of the paper is " Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis. " Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/38745337/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Here are...

#8 APOE4 and Alzheimer's disease 15.05.2024

In this episode, I cover a paper by Wang et al., 2021. The title of the paper is "Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia . " Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/33831349/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Her...

#7 Neuroinflammation in Alzheimer's disease 08.05.2024

In this episode, I cover a paper by Kummer et al., 2021. The title of the paper is "Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology . " Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/34825707/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Here is the webpage of the Heneka...

#6 How does the gut microbiome contribute to Alzheimer's disease? 01.05.2024

In this episode, I cover a paper by Grabrucker et al., 2023. The title of the paper is "Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis . " Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/37849234/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Here is the webpage of the Nolan lab: https://...

#5 Alzheimer's disease, amyloid plaques and tau tangles 24.04.2024

In this episode, I cover a paper by Zeng et al., 2023. The title of the paper is " Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease. " Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/36732642/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Here is the web...

#4 Oxygen imaging of hypoxic pockets in the mouse cerebral cortex 17.04.2024

In this episode, I cover a paper by Beinlich et al., 2024. The title of the paper is "Oxygen imaging of hypoxic pockets in the mouse cerebral cortex." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/38547288/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. Here is the webpage of the Nedergaard lab: https://www.urmc.rochester.edu/labs/ned...

#3 Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures 10.04.2024

In this episode, I cover a paper by McCafferty et al., 2023. The title of the paper is "Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures" Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/36627270/ . You may access the paper by clicking on the icons under the "Full Text Links" tab. You may have noticed that the...

#2 Improvement of sensory deficits in fragile X mice by increasing cortical interneuron activity after the critical period 03.04.2024

In this episode, I cover a paper by Kourdougli et al., 2023. The title of the paper is "Improvement of sensory deficits in fragile X mice by increasing cortical interneuron activity after the critical period." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/37451263/ . You may access the paper by clicking on the CellPress OpenAccess icon under the "Full Text Links" tab. You...

#1 Dopamine pathways mediating affective state transitions after sleep loss 27.03.2024

In this episode, I cover a paper from Wu et al. , 2024. The title of the paper is "Dopamine pathways mediating affective state transitions after sleep loss." Here is a PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/37922904/

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