The Human Upgrade: Biohacking for Longevity & Performance

IN THIS EPISODE OF THE HUMAN UPGRADE™…  you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people  thrive . Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering w...

Neurohacker Collective  sponsored this episode. IN THIS "UPGRADE SPOTLIGHT" EPISODE OF THE HUMAN UPGRADE ™… you’re going to learn about the zombie cells taking up valuable space in your body and how you can clear them out with senolytics. When these zombie cells accumulate (formally called senescent cells), they negatively impact how you age. You may experience symptoms like joint discomfort,...

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... the new year starts off with a Legacy Upgrade conversation between Dave Asprey and  Dr. Andrew Weil  recorded live at  True Food Kitchen  in Phoenix, Arizona.  Dr. Weil’s an internationally known pioneer and leader in integrative medicine. He’s also a Harvard-trained botanist and medical doctor recognized worldwide for his views o...

IN THIS EPISODE OF THE HUMAN UPGRADE™… Humble The Poet joins the show to talk about a unique perspective on love. You’ll learn: what “real” love means (hint: it’s not found or earned) and how to recognize it in your life.  how to shift away from a mindset of earning more, achieving more, and gaining more attention so you can clear pathways for love to enter and flourish in your life how to di...

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… …  Ari Whitten, Ph. D. (Cand.), CES, PES , explains how to double your energy through improved resilience, cell defense, nutrition and supplementation.   In his newest book, “ EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy ,” Ari explains that 5.4 millio...

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… …  Steven Gundry, M.D. , explains that ketones aren’t the fat-burning molecules you think they are. Ketones actually work to enhance health, weight loss, and longevity by acting as signaling molecules that stimulate your mitochondria. A cellular process known as “mitochondrial uncoupling” happens.  He debunks common myt...

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™ … natural vision expert  Claudia Muehlenweg  explains how you can take better care of your eyes and improve your vision.  Her work is based in the  Bates Method . She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually can make eyesigh...

In this Episode of The Human Upgrade™ … Dave talks with Rachelle Copeland about putting her energy into healing facial injuries and building new tissues—starting with the central nervous system. Rachelle experienced an accident that injured her face, teeth, nerves and jaw. She wants to heal quickly and avoid scarring and long-term damage while also managing the accompanying emotional trauma. This...

Viome  sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™…  entrepreneur and philanthropist Naveen Jain joins the show in person at the Beverly Hilton to talk about new developments in the human biome—particularly the oral microbiome. Turns out, there may be more  density  in your gut microbiome, but there’s more  diversity  in your oral microbiome. Naveen’...

Pendulum sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™ …molecular biologist and biochemist Colleen Cutcliffe, Ph. D., returns to the show with brand new science about your gut. She’s a regular guest because she and her team at  Pendulum  continue to uncover innovative ways to improve your gut health, your metabolism, your immune system, how your brain works and how long y...

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll find out that kids are killing themselves more often and at younger ages. Suicide prevention expert Dr. Mark Goulston joins the show to discuss the very real and very urgent topics of youth mental health and suicide—from pre-teens to teens to young adults. These issues concern  everyone , not only families, educators or professionals who con...

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll learn about a new holistic framework for self-healing and how to heal yourself with prompts, tools and actionable tips. Using the tenants of holistic psychology, Nicole LePera, Ph. D., created a different way to reach people and equip them with the tools necessary to heal themselves. Holistic psychology focuses on the mind, body, and soul in...

IN THIS EPISODE OF THE HUMAN UPGRADE ™…  Dan Buettner  joins the show to talk about the origins and food foundations of Blue Zones. He discusses how they were discovered, what makes them different, and what’s changed for people living there over the past few decades. And the big question—is it still possible to live to 100? Dan, an explorer, National Geographic Fellow, award-winning jour...

( ZBiotics sponsored this episode.) IN THIS EPISODE OF THE HUMAN UPGRADE ™… you'll find out how to counter the sometimes rough morning after you have alcohol. The key is a new genetically engineered pre-alcohol probiotic drink. Great timing as you head into the holiday season of celebrations. Zack Abbott, CEO & co-founder of  ZBiotics , joins this 1,000th episode of the podcast...

In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Sperm that swim together increase their chances of fertilization Late-night eating is worse than you thought Metabolic markers can be measured through your sweat Eye movements during REM sleep co...

Timeline Nutrition  sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… immunologist Anurag Singh, M.D., Ph. D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria.  Urolithin A activates mitophagy and renews your mitochondria.  “It takes all the cellular garbage that...

IN THIS EPISODE OF THE HUMAN UPGRADE ™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. You’ll learn: how your microbiome continually evolves and why that matters to the state of your gut and body functions. how to strengthen the antiviral defenses located in your gut. why your body...

Eight Sleep  sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’ll learn about the intimate relationship between performance and sleep and how you can hack both with a combination of tech and lifestyle.  Matteo Franceschetti joins the show to talk about high performance—something he experienced in athletics, business and life. He was a competitive athlete in his nat...

BiOptimizers  sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… you're going to get into bed with the topic of sleep. Pretty much everyone’s favorite.  In this conversation, veteran biohacker and BiOptimers co-founder Matt Gallant returns to the show with some straight talk about how to get more and better sleep. He’s spent the big bucks—about $50K he estimates—explori...

Alitura Naturals  sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™…… you’ll learn about skincare ingredients that can either nourish or harm your skin. You’ll find out about standards in skin care products, what “clean beauty” means, and what to look for on product labels. Andy Hnilo, founder of Alitura Naturals, joins the show to talk about skin fitness from the inside out...

Analemma sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’re listening to a new Upgrade Spotlight series. Once a month, these shorter episodes feature guests who get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful ...

IN THIS EPISODE OF THE HUMAN UPGRADE ™… You’ll learn about the ways using a sauna can charge your energy, help you heal physical and mental health conditions—and science that backs that up.  Sunlighten  sponsored this episode. Connie Zack joins the show to talk about the far-reaching benefits of sauna use and what’s new in the field of infrared light. For more than 22 years, Connie...

IN THIS EPISODE OF THE HUMAN UPGRADE ™… Joe Polish , considered “the most connected person on the planet,” shares networking strategies that help you get what  you  want by giving people what  they  want. Dave Asprey recently connected with Joe in person to talk about Joe’s new book so you can use nine genius principles to turn your business—and your personal relationships—arou...

In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. • How (and why) brain cells transfer mitochondria to one another • How a newly discovered molecule stimulates hair growth • How a tired brain drives poor decision-making EPISODE SPONSOR:  Th...

IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’ll learn how a yoga practice can be a vehicle for inner transformation. This conversation looks past the popularity of yoga as a fitness trend and into its deeper potential for human development. You’ll also learn how yoga can be a way for you to explore your whole being—from physicality to emotions to thinking. “A yoga practice often can be the missing...