Medical News Podcast

Anisha B. Dua, MD, MPH and Duvuru Geetha, MD discuss evolving strategies in maintenance therapy for ANCA-associated vasculitis. In keeping with the goal of achieving sustained remission and minimizing relapse, they provide insight into the duration and dosing of maintenance therapy, as well as treatment options and monitoring.

Anisha B. Dua, MD, MPH and Duvuru Geetha, MD share their insights into the nuances of steroid reduction and steroid-sparing approaches in ANCA-associated vasculitis treatment protocols, including the clinical benefits of steroid reduction, options available, and which patients might be the best candidates for steroid reduction.

Drs. Diab and Patil discuss recent advances in treating HER2+ lung cancer that were presented at World Lung 2024 and ESMO 2024. They highlight the role of newer treatments and discuss treatment sequencing and response rates.

Drs. Dua and Geetha share their insights into the renal manifestations of ANCA-associated vasculitis, detailing how kidney function is affected. They also delve into the recent guideline updates on the diagnosis and management of ANCA-associated vasculitis.

Drs. Bilezikian and Cosman examine goal-directed strategies and treatment targets for the long-term management of fracture risk in patients with osteoporosis, including how they choose treatment goals for their patients within differing risk groups. They also discuss the importance of T-scores in assessing patient risk.

Drs. Cosman and Bilezikian continue their discussion by sharing how they determine whether treatment targets for their patients have been met and how that differs from treatment response. They explore how they evaluate patients with osteoporosis, how they utilize surrogate markers in their practices, and what their personal strategies are for achieving treatment goals.

Drs. Benjamin Schlechter and Harshabad Singh discuss HER2-low and ultralow in GI cancers, newer therapies targeting HER2, and testing methods for HER in GI cancers.

Drs. Benjamin Schlechter and Harshabad Singh discuss toxicities in gastroesophageal cancer treatment; explore HER2+ in biliary tract tumors; and touch on the challenges of developing therapies targeting HER2+.

A study links poor sleep quality with accelerated neurodegenerative changes, suggesting that persistent sleep disturbances may expedite brain atrophy, warranting early therapeutic interventions to support cognitive health. Concurrently, data from JAMA Network Open Psychiatry reveal that social media use has complex effects on youth mental health, with excessive screen time and cyberbullying increa...

Drs. Benjamin Schlechter and Harshabad Singh explore the role and function of HER2 in gastrointestinal cancers, with a focus on gastroesophageal and colorectal cancers.

Drs. Bilezikian and Cosman discuss the use of anabolic agents in patients with postmenopausal osteoporosis, including the benefits and challenges of utilizing anabolic agents as well as the need for careful patient selection, education. and monitoring. They also review the mechanisms of action, clinical trial data, and rationale of treatment sequencing.

Drs. Cosman and Bilezikian discuss the optimal use of denosumab in patients with postmenopausal osteoporosis and examine how RANK ligand inhibitors differ from bisphosphonate medications. They also share insight into how they personalize therapy with denosumab in patients with postmenopausal osteoporosis.

Drs. Dietrich and Holloway continue sharing their insights into the pivotal role of HER2 positivity in gynecologic cancers. They discuss how HER2, a well-known biomarker in breast cancer, is increasingly recognized for its significance in other gynecologic malignancies, including ovarian and endometrial cancers.

Drs. Dietrich and Holloway share their insights into the pivotal role of HER2 positivity in gynecologic cancers. They discuss how HER2, a well-known biomarker in breast cancer, is increasingly recognized for its significance in other gynecologic malignancies, including ovarian and endometrial cancers.

Martin Dietrich, MD, PhD and Robert Holloway, MD continue their conversation about the biological and clinical significance of HER2+ receptors in these diverse malignancies, collectively referred to as pan-tumors, as well as the implications of HER2 that are crucial for advancing approaches to diagnosis, treatment, and patient care across various cancer types.

Drs. Holloway and Dietrich discuss the biological and clinical significance of HER2+ receptors in these diverse malignancies, collectively referred to as pan-tumors, as well as the implications of HER2 that are crucial for advancing approaches to diagnosis, treatment, and patient care across various cancer types.

Dupilimab received FDA approval as the first biologic treatment for adults with uncontrolled COPD, reducing exacerbations significantly in clinical trials. A study in JAMA Internal Medicine demonstrated that improper arm positioning during blood pressure measurements can lead to overestimated readings, potentially causing misdiagnosis. Another study in Atherosclerosis, Thrombosis, and Vascular Bio...

Dr. Daniel Daneshvar discusses the long-term consequences of traumatic brain injuries (TBI), particularly focusing on athletes and military veterans. Brain injuries like concussions often go unreported, and the cumulative impact of multiple hits, even non-concussive ones, can lead to neurodegenerative diseases such as Chronic Traumatic Encephalopathy (CTE). We discuss preventive measures, such as...

In a cross-sectional analysis from the CONSTANCES cohort study, hearing loss in middle-aged French adults was linked to increased odds of cognitive impairment. Although hearing aid use did not significantly lower the odds of cognitive decline overall, it did show benefits for those with depression. The World Health Organization recommends vaccinating pregnant women in their third trimester to prot...

Dr. Wright discusses key studies regarding medical outcomes in cardiac arrest, surgical patient care, and advanced lung cancer treatment. A GEMMA Network Open study highlights that anterior-posterior defibrillator pad placement improves return to spontaneous circulation in out-of-hospital cardiac arrests compared to anterior-lateral placement, although it did not affect survival rates to hospital...

Drs. Cooper and Ailani conclude their discussion from the 2024 AAN annual meeting in Denver, Colorado. In this final episode, they share their thoughts on results of research into vaporized cannabis for acute migraine, as well as a headache and suicide study from Denmark.

Drs. Cooper and Ailani continue their discussion from the 2024 AAN annual meeting in Denver, Colorado. In this second episode, they cover the results of the OVERCOME and TANDEM trials; understanding patients’ journeys prior to initiating CGRP inhibitors; and the prevalence and characteristics of menstrual migraines.

Join Wade Cooper, DO and Jessica Ailani, MD as they share highlights from the 2024 American Academy of Neurology (AAN) annual meeting in Denver, Colorado. In this first episode of a three‑part series, they discuss acute medication overuse in people with migraine, strategies to help patients to avoid overuse, and layering migraine therapies, among other topics.

Eric J. Eross, DO and Amaal J. Starling, MD, FAHS, FAAN discuss preventive strategies in migraine management, especially for individuals experiencing frequent and severe episodes that impair their functionality or quality of life. They also explore when to consider prevention (rather than just treatment) of acute episodes and preventive strategies.

The latest FDA approval of FluMist, a nasal spray influenza vaccine that can now be self-administered or given by caregivers for individuals aged 2 to 49 years. A systematic review found that while skeletal muscle relaxants (SMRs) like baclofen and cyclobenzaprine offer short-term relief for certain pain conditions, their long-term effectiveness remains questionable. Another study evaluated 24-hou...