MedEvidence! Truth Behind the Data

Send us Fan Mail Dr. Michael Hafran joins Dr. Michael Koren to discuss new investigational gene editing therapies. They talk about what genes and gene editing are, the history of gene editing, and some of the FDA-approved therapies on the market today. They also address fears people have about gene editing and clinical trials, explain the long and intensive safety measures in place, and reveal tha...

Send us Fan Mail Leslie Byatt joins Dr. Michael Koren to talk about leadership in the clinical research space. The two research professionals discuss the importance of qualified researchers in a research trial and the qualities that make for a good clinical research leader. They also talk about research as a treatment option and the benefits observed in research patients (even those in the placebo...

Send us Fan Mail A Cardiologist & Nephrologist Go Head-to-Head, er... "Heart-to-Kidney" Nephrologist Dr. Ali Rawabdeh joins Cardiologist Dr. Michael Koren to debate which is the bigger contributor (and problem) with high blood pressure: the heart or the kidneys. The two doctors discuss this extremely prevalent condition from their competing perspectives and give information on how di...

Send us Fan Mail Cardiologists Dr. Seth Baum and Dr. Michael Koren discuss the newly released top-line results from a big Lp(a) study investigating the effects of the drug pelacarsen. They talk about what Lp(a) is, why it matters, happened in the study, and what this means for other pelacarsen and Lp(a) studies worldwide. They take a deep dive into some of the factors that can reduce the effective...

Send us Fan Mail Dr. Mitchell Rothstein explains that GLPs have been with us for thousands of years. He gives a brief overview of how these medications work, some of the side effects they can cause, and to mitigate things like muscle loss and GI issues through exercise and dose management. Be a part of advancing science by participating in clinical research . Have a question for Dr. Koren? Email h...

Send us Fan Mail Dr. Mitchell Rothstein joins Dr. Michael Koren to discuss a current trend in unapproved medicine: peptides. They investigate what peptides are, why they have become so popular, and the very real problems with getting off-market medicines through the "grey market." They also talk about the history of peptides, including why they were banned from compounding pharmacies and...

Send us Fan Mail Dr. Steve Dorman joins Dr. Michael Koren to talk about vaccines, vaccine hesitancy, and the impact of politics on one of our most effective tools against disease. The doctoral duo, recorded in front of a live audience, talk about the big impacts of vaccines, including wiping out entire diseases like smallpox. They continue by cataloging success stories of vaccines, vaccine efficac...

Send us Fan Mail Dr. John Shufeldt joins Dr. Mitchell Rothstein to discuss his life and the need for change in the US healthcare system. Dr. Shufeldt talks about the changes he has made in the healthcare space, from starting urgent care clinics in the 1990s to his healthcare venture capitol to his focus on indigenous populations and training the new generation of doctors. The two discuss the need...

Send us Fan Mail In this MedEvidence rebroadcast, Dr. Albert Lopez explains lipoprotein(a), a genetically determined heart disease risk factor which still strikes people with “good” cholesterol. He also explains that plaque behaves like an inflammatory volcano that can rupture without warning. Dr. Lopez goes into how lipoprotein(a) increases the risk of heart attack, stroke, and aortic valve disea...

Send us Fan Mail Cardiologist and Clinical Researcher Dr. Michael Koren joins Eric Ross from " What the Health Just Happened " to talk about a wide range of topics. They discuss the history of clinical research in healthcare, the changing landscape of research in America and around the world, what's healthy (and what's not) in popular culture, and the emerging field of gene edi...

Send us Fan Mail Dr. Michel Koren and Dr. Mitchell Rothstein host a presentation in front of a live audience to discuss the current state of gene editing. The doctoral duo discuss developments including new-to-market medical therapies, clinical trials, and the legal issues surrounding gene therapy patents. They also explain the difference between gene silencing techniques, which temporarily stop g...

Send us Fan Mail Dr. Robin Blackstone joins Dr. Mitchell Rothstein to talk about the intersection of technology, empathy, and the healthcare system. The doctoral duo discuss the emerging role of AI in healthcare and how specialized, individualized, non-chatbot systems may be able to sift through the masses of health data that plague doctors to provide individualized, patient-specific recommendatio...

Send us Fan Mail Join internist and cholesterol expert Albert Lopez, DO, FACP, FASPC, as he reviews the new 2026 Cholesterol Guidelines. In this segment, he focuses on new risk assessment guidelines, including the genetic risk factor Lipoprotein(a) and a sign of damage, the CAC score, and the recommendation that risk assessment starts much younger, around 30 years old. He discusses treatment optio...

Send us Fan Mail Allergist and immunologist Dr. Steve Dorman joins Dr. Michael Koren to discuss the causes, complications, and carousel of chronic cough. Dr. Dorman reviews what chronic cough is and how it may be due to anatomical changes, acid reflux, allergies, and so on. Because of this, the doctor explains, sufferers of cough may end up going around the "carousel" of chronic cough, w...

Send us Fan Mail OBGYN Dr. Richard Myers joins Dr. Erich Schramm to discuss the name change from Polycystic Ovarian Syndrome (PCOS) to Polyendocrine Metabolic Ovarian Syndrome (PMOS). This syndrome is the combination of three parts: increased polyendocrine hormones (like insulin and androgens), changing metabolism, and differences in ovarian function Dr. Myers explains that the name change to PMOS...

Send us Fan Mail Dermatologist Dr. Michael Bernhardt joins Dr. Mitchell Rothstein to discuss the rapidly changing and improving world of chronic skin condition. The two doctors discuss the correlation between chronic skin conditions and allergies, and the role that inflammation play in both. The docs then dive deep into our inflammation system. This informs the next section of the podcast, where t...

Send us Fan Mail Nearly a decade after the last major cholesterol guidelines were released, the new 2026 Multi-Specialty Lipid Guidelines introduce significant changes in how cardiovascular risk is assessed and managed. In this episode, Albert Lopez, DO, FACP, FASPC, explains why LDL cholesterol treatment goals have returned, how newer markers such as ApoB and Lipoprotein(a) are reshaping risk ass...

Send us Fan Mail In this episode of MedEvidence, host Dr. Michael Koren speaks with epidemiologist Dr. Hannah Gardener about how everyday exposures may influence long-term health outcomes. Dr. Gardener shares her journey from neuroscience and epidemiology training at Harvard to her current work studying stroke, dementia, and environmental risk factors. She explains how personal life experiences sp...

Send us Fan Mail What do island-hopping physicians, aviation safety, sleep medicine, and nasal polyps have in common? Dr. Adam Shapiro. In this episode of the MedEvidence Podcast, Dr. Michael Koren sits down with ENT specialist and sleep medicine expert Dr. Adam Shapiro to discuss his remarkable career practicing medicine in the U.S. Virgin Islands, commuting between islands as a pilot, and helpin...

Send us Fan Mail What happens when a Harvard-trained psychiatrist follows the evidence beyond traditional medicine? In this episode of MedEvidence, Dr. Michael Koren sits down with Dr. Carol Locke, physician entrepreneur and Chief Science Officer of OmegaBrite, to explore her remarkable journey from psychiatry and academic research at Harvard’s McLean Hospital to pioneering evidence-based omega-3...

Send us Fan Mail When T.J. Sharpe was diagnosed with stage 4 melanoma at just 37 years old, the statistics were devastating. With a newborn son, a two-year-old daughter, and limited treatment options available at the time, he faced a life-changing decision: pursue standard chemotherapy or take a chance on early immunotherapy clinical trials. In this powerful episode of the MedEvidence Podcast, car...

Send us Fan Mail Watch the recorded presentation of “The Liver Fats Domino Effect” featuring Dr. Mitchell Rothstein and Dr. Michael Koren. In this educational luncheon event, the speakers discuss how fatty liver disease can progressively worsen over time, from early fat accumulation in the liver to inflammation, fibrosis, cirrhosis, and, in severe cases, liver transplant. This presentation also ex...

Send us Fan Mail Snoring might be the sound you notice, but the real danger of obstructive sleep apnea is what you don’t hear: your brain repeatedly yanking you out of deep sleep to keep you breathing, over and over, all night long. Dr. Mitchell Rothstein, a board-certified pulmonary and sleep medicine physician, joins us to give a clear update on what modern sleep medicine understands about sleep...

Send us Fan Mail Javonte Maynor joins family doctor and medical marijuana expert Dr. Erich Schramm to discuss the changing space of marijuana research and medical marijuana in the United States. The duo discuss the frustration with politics entering the medical space when it comes to marijuana, and how changing administrations can delay research. The two get into the nuts and bolts of marijuana re...

Send us Fan Mail Welcome to the MedEvidence Monday Morning Radio Show, hosted by Kevin Geddings of WSOS and Augustine Radio, and powered by ENCORE Research Group. Each Monday morning, Dr. Michael Koren calls in to bring you the latest medical updates with a insightful discussions. MedEvidence is where we help you navigate the real truth behind medical research, both a clinical and research perspec...