LEVELS – A Whole New Level

Biosensing offers people real-time insight into their health status. Regular insight, rather than one-time results at an annual checkup, helps people assess how lifestyle factors are impacting their health, whether they need to make adjustments, and which adjustments might have the most impact. Michael Dubrovsky and Josh Clemente discuss the value of biosensing and how it has the potential to disr...

We often think that arthritis, musculoskeletal pain, and degenerative joint issues are an inevitable result of aging—but this is far from the truth. Good metabolic health can have significant positive effects on bones, muscles, and joints, and can improve longevity. Conversely, poor metabolic health accelerates the degeneration of joints and tissues for many reasons, like the impact of high uric a...

Fructose and its byproduct uric acid may play a role in the development of Alzheimer’s, thanks to an evolutionary adaptation hijacked by the modern diet. Fructose can be directly consumed, or the body can convert high-glycemic carbohydrates and other foods to fructose. Fructose suppresses some cognitive functions. Dr. Richard Johnson and Dr. Rob Lustig discuss a new study, of which Johnson was an...

The elevation of uric acid in the body is a causative mechanism in the development of metabolic diseases and contributes to weight gain and fat production. Uric acid is one of the key links between obesity, diabetes, heart disease, neurologic diseases like dementia, ADHD, non-alcoholic fatty liver disease, and more. Dr. David Perlmutter talks with Dr. Casey Means about why we have excess uric acid...

Receiving a diagnosis of a chronic condition, such as Type 1 diabetes, can be life-changing. A diagnosis is helpful for understanding the cause of symptoms and how to treat, but managing a chronic condition can take a toll on mental health. Tools like a continuous glucose monitor can help empower people and ease the burden of constant care. Jesse Lavine and Ben Grynol discuss the challenges of man...

A metabolic blood test and cholesterol panel can be confusing, so in this ultimate guide, our Chief Medical Officer and Co-Founder Dr. Casey Means talks with Levels advisor and author of Metabolical to give you advice on how to interpret your panels to better understand the status of your metabolic health. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversati...

How does pregnancy affect your metabolic health at each trimester, from conception to postpartum lactation? Levels Research Design Lead Dr. Azure Grant talks with Ben Grynol about the different phases of pregnancy and how it affects hormones and things you can do to reduce the risk of gestational diabetes. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversati...

Insulin resistance is when cells stop responding to insulin’s signal to uptake glucose. It’s a hallmark of prediabetes, Type 2 diabetes, and other forms of metabolic dysfunction, and it manifests as several chronic disease, ranging from Alzheimer’s to polycystic ovarian syndrome. Dr. Rob Lustig and Dr. Dominic D’Agostino discuss the importance of monitoring insulin levels, why a high or increasing...

High-carbohydrate diets and carbohydrate loading have been long-standing tenets of athletic training and competition, but newer research indicates a low-carbohydrate diet may be more beneficial for performance and overall health. Professor Tim Noakes and Josh Clemente discuss how a fat-adapted body can rely on fat as a fuel source at all exercise intensity levels, rather than burning mostly carboh...

Society champions multitasking, but we can’t truly multitask. Multitasking in fact impedes our focus and productivity. And 12 main factors tend to steal our attention. Johann Hari and Ben Grynol discuss why flow states are important for goal achievement, the things that distract us, and how we can reclaim our focus. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels...

Regenerative farming harnesses a farm’s entire ecosystem to grow and raise food via natural processes. In turn, foods raised on regenerative farms benefit our bodies more so than those raised conventionally. Molly Chester of Apricot Lane Farms and Dr. Casey Means discuss the philosophies of regenerative farming, how the practice has parallels with functional medicine, and how regenerative farming...

Gastrointestinal health, metabolic health, and fertility are all linked. The gut microbiome impacts other microbiomes in the body, which can then impact the ability to conceive. Our gut microbiomes are becoming less diverse through modern farming practices and the consumption of processed foods. Dr. Robin Rose and Ben Grynol discuss how gut microbiome testing can determine underlying factors of ga...

Concierge medicine can help personalize healthcare and disrupt the traditional primary care model. Traditional primary care isn’t positioned to handle the frequent check ins and actionable steps that empower patients to optimize their health and wellness. Chloe Harrouche and Mike Haney discuss The Lanby, which Harrouche co-founded. The Lanby’s primary care membership provides patients with a three...

The ketogenic diet, intermittent fasting, and other nutritional strategies for metabolic health are unique when it comes to the female body. Hormonal changes over the menstrual cycle trajectory matter. Dr. Stephanie Estima and Dr. Lauren Kelley-Chew discuss women’s metabolic health, how to time nutritional strategies with the menstrual cycle, and why strength training is key. Sign Up to Get Your F...

The hallmarks of aging are various biomarkers that indicate advancing biological age, which leads to a decline in health and eventually to death. But we can boost longevity by understanding aging biomarkers and then taking actionable steps with nutrition, physical activity, and environment. Dr. Mark Hyman and Dr. Casey Means discuss the hallmarks of aging and the factors that are within our contro...

According to Peter Diamandis, MD, we’ll make more technological progress and breakthroughs in the next 10 years than in the past 100, including current developments in fusion, humanoid robots, avatars, and ChatGPT. Listen as Levels Founder Josh Clemente talks with Peter Diamandis about technological breakthroughs and what they mean for the future of medicine, and how to shift your mindset as an en...

We can think of our energy capacity as like the currency in our bank accounts that helps support us. Low energy capacity is an indicator of mitochondrial dysfunction—the decline in in how well our cells produce and use energy. It can lead to chronic disease. Dr. Molly Maloof and Dr. Lauren Kelley-Chew discuss how to optimize mitochondrial functioning for better overall health and well-being to pre...

Jeff Krasno, CEO and founder of Commune, experienced chronic fatigue and brain fog earlier this year and discovered he had prediabetes. He used Levels to learn more about his blood glucose and metabolic health and now enjoys metabolic flexibility. Sonja Manning chatted with Jeff about his health journey, his dietary changes, intermittent fasting, and his other learnings from the metabolic health w...

How is functional medicine different from traditional healthcare? Functional medicine focuses on patient-facing time and individual biomarkers for forming a comprehensive, individualized plan to empower people in matters of their health and well-being. The Western medicine model often leaves much to be desired when it comes to building a long-term relationship with a patient that helps foster thei...

Branding isn’t just about the visual identity of a company. In this episode, Ben Grynol talks with Nik Sharma, “The DTC Guy” who runs Sharma Brands and HOOX, about what it means to build a good brand in the direct-to-consumer marketing space. Nik points out the crucial thing to remember is that no one remembers your brand unless you’re one of the top global brands, so it’s best not to get overly i...

Team members at a company want honesty, transparency, and a clear progression path to know how to get to the next level in their careers. It’s reasonable for people to want to see progress and want more money and recognition, and so here at Levels we want to make career paths explicit to encourage growth and limit staff turnover. This chat between Nicole Miller and Sam Corcos is about high trust b...

Cleo Abram found her passion for content creation and independent journalism when she started her YouTube channel Huge If True, a journalistically rigorous show with optimistic explainers about tech that could change our future. Listen as Cleo and Ben Grynol talk about the tension between the quality of work you publish versus the velocity, a bottom-up versus top-down content creation approach, an...

Over the lifespan of Levels, the company and the CEO role evolved drastically. Sam Corcos went from coding the initial product to CEO, and he experienced a lot of personal challenges and growth along the way. Listen as Sam chats with Ben Grynol about time management, strategy versus people ops, requirements at each startup stage, and taking time to reflect through quarterly Think Weeks. Sign Up to...

We often think that arthritis, musculoskeletal pain, and degenerative joint issues are an inevitable result of aging—but this is far from the truth. Good metabolic health can have significant positive effects on bones, muscles, and joints, and can improve longevity. Conversely, poor metabolic health accelerates the degeneration of joints and tissues for many reasons, like the impact of high uric a...

When doing a big push for hiring in engineering and software development, it can help to enlist the help of international recruiting agencies who can help source top talent from around the world. In this episode, Sam Corcos gets advice from Sudeep Sidhu from Neo Financial about some best practices for hiring engineers and how highly rated agencies and hack days can help assess talent. Sign Up to G...