The Feldman Protocol

In this episode of The Feldman Protocol, can the principles of metabolic flexibility reframe how athletes — and everyday people — think about fueling exercise? Dave Feldman sits down with Bronson Dant (metabolic performance coach and doctoral candidate in health science), who makes the case that food is function, not fuel. Bronson discusses his Army nutrition research experience, his carnivore die...

In this episode of The Feldman Protocol, what does emerging research actually reveal about cardiovascular risk in people who develop extreme LDL elevations on ketogenic diets — and how much remains genuinely unresolved? Zachary DiMattia (nutritional scientist, Penn State) joins Dave to discuss his published review on ketogenic diet–induced LDL elevations in normal-weight adults, presents prelimina...

In this episode of The Feldman Protocol, can what we eat meaningfully influence the course of serious mental illness? Dave sits down with Lauren Kennedy West (mental health advocate and YouTuber living with schizoaffective disorder) to explore her personal journey from multiple hospitalizations and misdiagnoses to adopting therapeutic ketosis. Lauren makes the case for metabolic psychiatry as a co...

In this episode of The Feldman Protocol, how does metabolic health shape cardiovascular risk — and does the conventional focus on individual biomarkers miss the bigger picture? Dave Feldman sits down with cardiologist Arthur Agatston (MD), creator of the South Beach Diet and the coronary calcium score, to explore blood pressure guideline debates, insulin resistance and preeclampsia, the origins of...

In this episode of The Feldman Protocol, how does metabolic health shape cardiovascular risk — and what does that mean for interpreting cholesterol markers in lean, low-carb individuals? Arthur Agatston (MD) makes the case for a functional model of atherosclerosis progression, discusses AI-driven advances in cardiac imaging, argues for revisiting how blood pressure is measured and treated, and exp...

In this episode of The Feldman Protocol, how well do conventional cardiovascular risk metrics actually identify who is truly at risk for a heart attack decades before it happens? Cardiologist Arthur Agatston (MD) makes the case for coronary calcium scoring as an early detection tool, discusses the natural history of atherosclerotic plaque, revisits key moments in lipid science history, explores wh...

In this episode of The Feldman Protocol, how does insulin influence cancer cell behavior — and what does that mean for metabolic approaches to the disease? Dave sits down with Isabella Cooper (PhD) to explore the glucose-ketone index and its practical limits, the role of glutamine alongside glucose in cancer metabolism, how mitochondrial dysfunction and cardiolipin loss may relate to tumor progres...

In this episode of The Feldman Protocol, what does beta-hydroxybutyrate between meals actually reveal about a person's insulin state — and why might that matter for understanding chronic disease risk? Dave sits down with Isabella Cooper (PhD), a biochemistry and pathophysiology scientist whose research spans assay quality control, hyperinsulinemia detection, ketone thresholds, mitochondrial fu...

In this episode of The Feldman Protocol, how much does metabolic health shape cardiovascular risk beyond what standard lipid markers can reveal? Dave Feldman sits down with Scott Murray (MD), a UK-based interventional cardiologist, to explore plaque imaging and its limitations, the role of visceral and perivascular fat in heart disease, the lipid energy model and lean mass hyper-responders, cardia...

In this episode of The Feldman Protocol, what actually drives cardiovascular disease in a metabolically healthy, lean individual — and is elevated LDL the most important variable to consider? Darius Sharpe (ER nurse and lean mass hypersponder community member) discusses his unexpected CAC score at age 38, his theory on postprandial glucose and vascular damage, a personal episode of atrial fibrilla...

In this episode of The Feldman Protocol, how well does the prevailing understanding of LDL and cardiovascular disease hold up under close scrutiny? Dave sits down with Malcolm Kendrick (MD) — author, researcher, and longtime cardiovascular disease skeptic — who challenges key assumptions across trial methodology, observational data, Mendelian randomization, clinical trial blinding, nitric oxide&#3...

In this episode of The Feldman Protocol, what does it take to recognize and address a compulsive relationship with food — and why does that recognition matter so much? Jen Unwin (clinical and health psychologist) joins Dave to explore the psychology of hope in medical settings, her personal history with carbohydrate-driven food behaviors, the evidence behind ultra-processed food addiction as a pro...

In this episode of The Feldman Protocol, how does one family doctor's decades-long frustration with a "progressive, incurable" disease lead to a fundamentally different approach to patient care? Dave Feldman and David Unwin (MD) explore the pivotal 2012 patient encounter that reshaped Unwin's practice, the psychology of behavior change and food addiction, real-world data from a 1...

Part 1 of 2In this episode of The Feldman Protocol, what can a quarter-century of emergency medicine experience reveal about the everyday habits quietly shaping metabolic health outcomes? Darius Sharpe (ER nurse and former paramedic with 24 years in emergency medicine) makes the case that postprandial glucose excursions deserve far more clinical attention, discusses his personal glucose experiment...

In this episode of The Feldman Protocol, can a practicing family physician's personal health crisis reshape the dietary advice he gives to thousands of patients? Ken Berry (MD) makes the case for low-carbohydrate approaches in managing metabolic conditions, shares his path from rural Tennessee to family medicine, discusses founding the American Diabetes Society as an alternative institution, explo...

In this episode of The Feldman Protocol, can elite athletes truly thrive on fat alone — with zero carbs? Dave sits down with Casey Ruff (personal trainer, nutrition coach, and host of Boundless Body Radio) to explore his journey from gym kid to keto rebel, high-intensity training principles, a rogue low-carb experiment inside a corporate fitness company that produced 732 lbs of fat loss, the LMHR...

In this episode of The Feldman Protocol, can a for-profit assisted living home actually send residents back home healthier than when they arrived? Hal Cranmer (assisted living owner and metabolic health advocate) makes the case that ketogenic and carnivore nutrition, resistance training, hyperbaric oxygen therapy, and disciplined deprescribing can reverse diabetes, restore cognition, and rebuild i...

In this episode of The Feldman Protocol, how does a physician's personal and professional crucible shape an unconventional approach to metabolic medicine? Annette Bosworth (MD) joins Dave to discuss her legal battles and U.S. Senate campaign, her mother's experience with a ketogenic dietary intervention, the behavioral psychology behind lasting dietary change, her structured 21-day intensi...

In this episode of The Feldman Protocol, what does a physician's journey through rural medicine, corporate bureaucracy, and scientific controversy reveal about how the healthcare system handles innovation? Dave Feldman sits down with Annette Bosworth (MD), an internal medicine physician and author, who discusses her origin story in small-town South Dakota, the role of lifestyle factors in pati...

In this episode of The Feldman Protocol, how much does mitochondrial energy metabolism shape long-term health outcomes — and what does that mean for how we interpret cardiovascular, immune, and metabolic research? Dave sits down with Chris Masterjohn (PhD) to explore his mitochondrial testing company and what enzyme-complex patterns may reveal about individual nutritional needs, his longstanding m...

In this episode of The Feldman Protocol, Dave Feldman sits down with Peter Ballerstedt (PhD) — forage agronomist and founder of Grass Based Health.🔥 This episode is sponsored by us --Own Your Labs 👉 `https://ownyourlabs.com/sp/34` Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own compan...

In this episode of The Feldman Protocol, can the environment you go home to matter more than the brain injury itself? Tommy Wood (MD PhD) makes the case that how you use your brain is the primary driver of how it functions — then digs into CTE mechanics, the myth of the brain "sloshing" in the skull, why animal models of concussion may fundamentally miss the point, ketogenic diets and me...

In this episode of The Feldman Protocol, can a diet of almost exclusively meat actually support world-record athletic performance while raising serious questions about conventional cardiovascular risk? Shawn Baker (MD) traces his path from professional rugby and military trauma surgery to pioneering the carnivore movement, makes the case for carnivore as a powerful elimination diet for autoimmune...

In this episode of The Feldman Protocol, can a ketogenic diet actually build a championship physique — or does elite bodybuilding demand carbs? Robert Sikes (natural pro bodybuilder and founder of Keto Brick) makes the case that fat adaptation outperforms conventional prep, sharing his journey through eating disorders, the origins of Keto Brick, his seven-phase protocol, reverse dieting, and the d...

In this episode of The Feldman Protocol, can living with an LDL of 700 for seven years actually leave your arteries plaque-free? Nick Norwitz (MD PhD) makes the case that the conventional cholesterol narrative is far more complicated than mainstream medicine admits, while Dave and Nick also cover the paternalistic medical system, statin side effects in women, Nick's surprising decision to take...