Nucleate Singapore Pulse

In part two of this episode, Dr. Elia Stupka explains why Angelini Ventures established a Singapore office: high-conviction “boots on the ground” in a rapidly transforming Asia, Singapore’s role as a multilingual, legally strong APAC base, and a maturing local ecosystem with A*STAR science and clinical excellence. He describes EspressoLab, created with Enterprise Singapore as a hands-on, transpare...

In this episode, Dr. Elia Stupka, Managing Director of Angelini Ventures, traces his path from early computational biology to venture capital. He describes pioneering days on the Human Genome Project in Cambridge, the startup-like pace of building genome annotation tools and infrastructure, and helping launch Singapore’s fugu genome project with Sydney Brenner. He also contrasts academia’s grant-a...

Jie Sun, Co-founder and CEO of ChemT Biotechnology, joins the show to discuss how artificial intelligence, virtual cell models, and small-molecule interventions could reshape biologics manufacturing. Drawing on a career spanning healthcare consulting, pharmaceutical project management, regulated healthcare AI, and entrepreneurship, Jie shares how her experience across Southeast Asia and the United...

Dr. Damien Keogh, Founder and CEO of BluMaiden Biosciences, joins the show to discuss how artificial intelligence, computational biology, and entrepreneurship are transforming drug discovery. Drawing on a career that spans molecular microbiology, academia, venture capital, and biotech company building, Damien shares his journey from studying microbial biology in Ireland to founding a Singapore-bas...

Dr. Katherine Wang, Deputy Director of the Biomedical Research Council and lead of the Singapore Therapeutics Development Review (STDR), joins the show to unpack what it really takes to move a scientific discovery from the lab bench to a viable biotech company. Drawing on a career that spans a PhD at NYU, tech transfer, program building at Duke-NUS, and now national drug-discovery strategy at A*ST...

Dr. Peter Fedichev is the co-founder and CEO of GERO , a Singapore-based biotech startup that uses physics-informed AI and massive human health datasets to discover drugs aimed at slowing down aging and treating age-related diseases. In the 2nd part of this episode, Peter explains how Gero builds generative models of human health to predict disease trajectories and identify shared biological drive...

Dr. Peter Fedichev is the co-founder and CEO of GERO , a Singapore-based biotech startup that uses physics-informed AI and massive human health datasets to discover drugs aimed at slowing down aging and treating age-related diseases. In this episode, explains his transition from a decade in theoretical physics to longevity biotech, motivated by applying physics tools to complex living systems and...

Dr. Boon Chong Goh is the co-founder and CTO of ArrowBiome , a Singapore-based biotech startup developing precision microbiome solutions through its lysin engineering platform. Spun out from the Singapore-MIT Alliance for Research and Technology and NTU Lee Kong Chian School of Medicine, ArrowBiome develops proprietary and patented platform technologies that enable highly selective bacterial targe...

Mr. Kit Yong is the co-founder of Forte Biotech , a Singapore-based agritech startup developing rapid, point-of-care molecular diagnostics for aquaculture. Forte Biotech was founded in 2021. The concept behind RAPID was inspired by the founders’ experiences working with farmers in Vietnam, as well as insights from their own family businesses. Having witnessed firsthand the challenges faced by farm...

Dr. Edison Liu is a medical doctor turned cancer geneticist, whose work focuses on cancer genomics, breast cancer biology, and translational medicine. He has held senior leadership roles in biomedical research institutions in the United States and Asia, as the founding executive director of the Genome Institute of Singapore (GIS), and later the president and CEO of the Jackson Laboratory, one of t...

Dr. Edison Liu is a medical doctor turned cancer geneticist, whose work focuses on cancer genomics, breast cancer biology, and translational medicine. He has held senior leadership roles in biomedical research institutions in the United States and Asia, as the founding executive director of the Genome Institute of Singapore (GIS), and later the president and CEO of the Jackson Laboratory, one of t...

Dr. Lewis Hong is the Vice President of Paratus Sciences, a biotech company uncovering novel therapeutics by studying the extreme biology of bats. With a background spanning genomics research, pigmentation genetics at Stanford, and leadership roles in translational sciences at MSD, Lewis brings deep scientific and industry expertise to this pioneering field.   In this episode, Lewis shares how Par...

Dr. Goh Wei Jiang is the Co-founder and CEO of CraftHealth , a pioneering Singapore-based startup revolutionizing personalized medicine through 3D printing. With a background in pharmacy and a PhD-MBA from NUS, Dr. Goh brings both scientific expertise and commercial insight to the forefront of MedTech innovation. Drawing on his clinical experience and translational research, he co-founded CraftHea...

Dr. Abbas Sahili is the CTO of Singzyme, a biotechnology company pioneering next-generation bioconjugation technologies. With a strong background in biochemistry and structural biology, Abbas brings deep scientific expertise and entrepreneurial vision to the field of precision medicine. His transition from academia to biotech leadership is marked by a commitment to developing antibody-drug conjuga...

Dr. Hoa Giang is the Co-founder and Data Science Lead of Gene Solutions. His background boasts a broad range of experience in the global therapeutics industry. His technical background includes computational biology, bioinformatics analysis and understanding genetic interactions and how they affect the cellular functions. This experience and immense knowledge inform his mindful and robust approach...

Dr. Ivan Horak is currently the CEO and founder of Tikva Allocell, a biotech company whose mission is to develop safe, effective, readily available and affordable “off-the-shelf” T cell therapies by leveraging excellent safety profile of proprietary technologies that enhance the T cell's performance to treat cancer. In this episode, Ivan shares his journey from having an interest in becoming a med...

Dr. Joshua Wang is currently the CEO and founder of VerImmune, a biotech company focused on developing novel virus inspired particle technology platform that can be used as a delivery system to target cancers. In this episode, Josh shares his journey from having an interest in infectious diseases to leading a biotech startup that spans across the US and Singapore. VerImmune specializes in developi...

Ritika Khetawat is the founder of MissionBridge, a fundraising advisory firm that empowers Singapore’s biotech and medtech ventures to secure the capital they need. In this episode, Ritika discusses her transition from investment banking at Goldman Sachs and Morgan Stanley to supporting healthcare startups through MissionBridge. She shares her insights into the unique challenges of biotech fundrai...

Dr David M. Epstein is the co-founder and president of PairX Bio, a company that specializes in the next generation of cancer selective biologics. In this episode, David shares his experience and journey from working in various biotech companies and big pharma institutions to eventually building his own companies. One of these is Pairx Bio, a company specializing in the next generation of cancer b...

Dr. Alessandro Falcone is the Head of JLABS Singapore. In this episode, Alessandro talks about his transition from clinical medicine to business consulting, eventually landing in leadership roles at major pharmaceutical companies. He explains the mission of JLABS Singapore, a collaboration between Johnson & Johnson and Singapore’s Economic Development Board, which aims to nurture early-stage b...

Loong Wang is the CEO and Co-Founder of QDX, a company specializing in computational drug discovery using quantum mechanics and supercomputing. In this episode, Loong discusses his journey from supercomputing at the Australian National University to founding multiple startups in distributed computing and blockchain—before making a significant pivot to biotechnology. His deep dive into quantum chem...

Fengru Lin is the Founder and CEO of TurtleTree, a pioneering biotechnology company that has successfully developed the world’s first sustainably produced lactoferrin “LF+” using precision fermentation technology. In this episode, Fengru Lin shares her journey from a tech career at Google and Salesforce to leading biotech innovations at TurtleTree. Inspired by challenges in replicating traditional...

Dr. Lisa Ooi is the Senior Vice President of Strategy at Hummingbird Bioscience, a leading biotech company in Singapore focused on antibody therapeutics. In this episode, Dr. Ooi discusses her journey from her PhD at Stanford to her current role, highlighting her experience in biomedical research and corporate strategy. She delves into Hummingbird Bioscience's innovative platform for developin...

Dr. Adam Gregory is a Partner and Patent Attorney at Mewburn Ellis LLP. He works with biotech companies to build and manage their patent portfolios, drafting patent applications and co-ordinating prosecution worldwide. In this episode, he highlights success stories from Singapore’s vibrant biotech scene, including Enleofen Bio and Hummingbird Bioscience, and discusses the evolving nature of patent...

Dr. Robert Ang is the CEO of Vor Bio, a clinical-stage cell and genome engineering therapy company. In this episode, Dr. Ang discusses the challenges of treating cancer, particularly acute myeloid leukemia (AML), and the need for new and innovative approaches. The conversation delves into the challenges of navigating clinical trials during the pandemic and securing funding for research and develop...