LEVITY

Tom Ough tells us about the Big Things that may end humanity - and what we can do and in some cases have done to prevent these. Did you know that if all the risks, the one that is most likely to end you is aging? What are we doing to stop aging? Tom is a journalist and writer who is currently Senior Editor at UnHerd, a London‑based online magazine of culture and opinion. After several years workin...

Today we’re diving into one of the strangest and most ambitious ideas in longevity: using crypto trading to fund real-time lifespan experiments. Benji Leibowitz, founder of pump.science, joins us to explain how decentralized science works, why tokens can finance studies in worms, flies and mice, and what happens when a single post on X suddenly turns Metformin into a viral experiment. That interve...

Valuable time is being lost because there is not enough funding for science with real life-extending potential. No major political party is promising to address aging, even though aging harms and kills more people than anything else. Most people—and most leaders—still do not understand that aging is both a problem and something that can be solved through science. We need a political movement that...

Sara Hägg, PhD is an associate professor at Karolinska Institutet, where she leads the Molecular Epidemiology of Aging Group. Her work focuses on human biomarkers of aging - especially biological age “clocks” built from epigenetic, proteomic, and metabolomic data - and on turning Nordic registry resources into clinically useful aging measures. In this episode: * What biological/epigenetic age cloc...

We are always excited about the next technological solution. But what if it does not come? Or what if it comes only for the few, or with terrible side-effects? And while we are waiting for the easy tech fix, are we neglecting what we can do now to better our lives? Many of our previous guests have been excited about the prospect of radically extending our lives, and some have been optimistic about...

One idea I’ve had lately is to put together a list of people to trust in geroscience and the longevity field more broadly. (And I might do it - keep an eye on reachlevity.com - and subscribe while you’re at it!) Matt Kaeberlein would not only make that list - he’d likely be right at the top. He’s rigorous, precise in his wording, and always puts integrity ahead of hype. But, and this is important,...

When you give a child a pet, you also expose them to death—since most pets pass away long before their owners. But what if we could cryopreserve Buddy or Tiger, and bring them back from suspended animation once we have a cure for what ended their lives? Kai Micah Mills is a pioneering figure in radical life extension and biostasis. As the founder of Cryopets, he is leading efforts to make cryopres...

As you may have heard, AI-designed medicines have crossed a historic line. In this episode, Alex Zhavoronkov - CEO of Insilico Medicine and founder of ARDD walks us through how Insilico’s rentosertib became the first AI-generated small molecule with peer-reviewed clinical efficacy, while arguing against AI hype and reminding us that biology still moves at “the speed of traffic.” That duality runs...

Anyone who is interesed in emerging science and futurism will come across the name Natasha Vita-More; a suggestive name for a charismatic and important philosopher and artist envisioning human possibilities. She wrote the Transhuman Manifesto in 1983. But did you know that she has also made a scientific discovery with big implications for cryopreservation? Natasha Vita-More is a trailblazing futur...

Even though it’s undeniably...aesthetic-challenged, the naked mole-rat is the envy of the longevity world. Its risk of death barely changes with time; it shrugs off cancer, stays fertile for decades and seems to skip every hallmark of aging that hobbles the rest of us. But why? What evolutionary forces gave a mouse-sized, subterranean rodent near-immunity to aging - and what can its biology teach...

🎁 Our giveaway is live! 10 winners will receive FMD kits from Prolon. It’s free to enter – just follow the link below 👇 https://gleam.io/NaVa0/prolon-fasting-mimicking-diet-giveaway 🔬 Can food rejuvenate you from within? In this special episode of LEVITY, Peter talks with Andrea Ghirardi, CEO of L-Nutra Europe — the company behind Prolon, the fasting-mimicking diet (FMD) developed from Dr. Valt...

When is someone really dead? What does it mean to survive? Is mind-uploading really a possible future way of surviving? These are some of the questions we are discussing with Dr Ariel Zeleznikow-Johnston. Dr Ariel Zeleznikow‑Johnston is a neuroscientist and Research Fellow at Monash University in Melbourne, Australia, whose work delves into the neural basis of consciousness - from understanding ho...

Just about the hottest thing in longevity science right now is partial reprogramming - using Yamanaka factors to rewind the biological clock in our cells. Billion-dollar giants like Altos, Retro and New Limit are betting on it. But in this episode a far smaller player, Shift Bioscience, argues that the field may be looking in the wrong place. CEO Daniel Ives explains how his team used AI-powered v...

We think that death is bad, but why exactly is it bad? We cannot suffer when we do not exist, so why would it be bad? In this episode we have a long, deep conversation with Professor Travis Timmerman, whose philosophical work delves deeply into the nature and ethics of death. An Associate Professor at Seton Hall University, Professor Timmerman has become a prominent voice in contemporary discussio...

There were two reasons why Dr. Valter Longo was featured so prominently in my longevity book Evigt Ung (2022). First, if you had to name a single scientific thread running through the history of longevity research, calorie restriction is hard to beat. And few have done more to modernize and translate that insight into real-world practice than Longo. Second, I hold Valter Longo in the highest regar...

This is our first — and probably our last — episode where the guest has brought with him an actual punch card and proceeds to explain why it is, in fact, caca (which is Spanish for 💩, by the way). Welcome to the wild world of José Cordeiro. Stick around and you might hear anecdotes about Robert Kennedy Jr. in Memphis 🎸, late-night karaoke sessions 🎤, and a man shouting “immortality!” to anyone...

Lately, there's been growing pushback against the idea that AI will transform geroscience in the short term. When Nobel laureate Demis Hassabis told 60 Minutes that AI could help cure every disease within 5–10 years, many in the longevity and biotech communities scoffed. Leading aging biologists called it wishful thinking - or outright fantasy. They argue that we still lack crucial biological data...

Peter Fedichev is a visionary scientist, biotech entrepreneur, and physicist at the forefront of longevity research. With a background in theoretical physics, he has seamlessly merged cutting-edge science with real-world applications, making groundbreaking contributions to the fields of aging, biotechnology, and artificial intelligence in healthcare. As the co-founder and CEO of Gero, a pioneering...

In this episode of LEVITY, we speak with Laurence Ion, a tech entrepreneur whose experience with a rare genetic disease led him to tackle one of humanity's greatest challenges: aging. Starting as a shy coder who 'couldn't talk to strangers,' Laurence has become a movement leader pioneering a bold new approach: creating specialized cities where extending human lifespan isn't just a goal - it's the...

We have another amazing guest for this episode: Anders Sandberg is a visionary philosopher, futurist, and transhumanist thinker whose work pushes the boundaries of human potential and the future of intelligence. As a senior research fellow at Oxford University’s Future of Humanity Institute until its closing in 2024 Sandberg explores everything from cognitive enhancement and artificial intelligenc...

In this in-depth conversation, Dr. Aubrey de Grey discusses his Robust Mouse Rejuvenation (RMR) studies at the LEV Foundation and why he believes we're close to achieving the crucial RMR milestone within just three years - a breakthrough that could transform aging research forever. You'll also hear about: His predictions for reaching Longevity Escape Velocity by the late 2030s What he would change...

Jamie Justice takes us inside the $101M XPRIZE Healthspan competition - one of the world's largest efforts to develop therapeutics that could reverse aging. As Executive Vice President of XPRIZE Healthspan, Jamie reveals how teams must demonstrate they can restore muscle, cognitive, and immune function in older adults within just one year. The stakes? $81M for achieving a 20-year reversal of aging...

A pediatric cardiac surgeon turned longevity pioneer, Dr. David Luu shares his journey from humanitarian medical missions to building a global network of physicians focused on prevention. Learn about critical health markers your doctor might be missing, how AI is transforming healthcare, the truth about longevity interventions, and why the future belongs to prevention rather than treatment. Plus,...

🚀 Special offer for our LEVITY audience: Join Vitalism today and receive a 30% discount on your membership using the code LEVITY at checkout. https://www.vitalism.io/membership 🚀 Show notes for this episode will be available soon after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: https://peterottsjo.beehiiv.com/ Meet one of the true legends of the longevity sp...

🚀 Special offer for our LEVITY audience: Join Vitalism today and receive a 30% discount on your membership using the code LEVITY at checkout. https://www.vitalism.io/membership 🚀 Show notes for this episode will be available soon after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: https://peterottsjo.beehiiv.com/ -- IN THIS EPISODE -- Nora Cavani, CEO of Alba H...