Good Medicine Podcast

What happens when a young heart is transplanted into an older body? And what happens when an older heart is placed into a younger one? In this episode of the Good Medicine Podcast, Dr. David Bearss and his brother Jeremiah discuss fascinating research using heart transplants to explore how our organs age. They look at evidence suggesting that when a younger heart is placed into an older biological...

Living longer sounds great. But what if those additional years are spent dealing with chronic disease, limited mobility, and declining health? In this episode of the Good Medicine Podcast, Dr. David Bearss and his brother Jeremiah discuss why the conversation around longevity is shifting away from simply extending lifespan and toward something potentially much more valuable: extending healthspan....

Could having a strong sense of purpose actually influence how long you live? In this episode of the Good Medicine Podcast, Dr. David Bearss and his brother Jeremiah discuss research connecting a strong sense of purpose with longevity and better health. They explore why having something meaningful to work toward may affect more than just how we feel. Purpose could influence our psychology, our dail...

Forgetting names, losing your train of thought, or feeling like your memory isn't as sharp as it used to be is often written off as a normal part of getting older. But how do you know when memory loss is normal and when it could signal something more serious? In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss explore what happens to memory as we age and how...

Energy drinks have a bad reputation. But are they actually bad for you? In this episode of the Good Medicine Podcast, Dr. Jeremiah Bearss sits down with internal medicine physician Dr. Brian Parker to separate what we know about energy drinks and caffeine from what gets repeated online. They discuss how the shift toward sugar-free energy drinks has changed the conversation, what caffeine actually...

Moderna and Merck just announced major Phase 3 results for their personalized mRNA cancer vaccine. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss break down the newly announced results from the Phase 3 INTerpath-001 trial in patients with high-risk melanoma. The trial met both of its primary endpoints, showing improvement in recurrence-free survival and dist...

The supplement industry is worth billions of dollars, but are supplements really the key to better health? In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss the science behind supplements, vitamins, protein, creatine, BPC-157, and the importance of building a strong health foundation before looking for shortcuts. They explain why nutrition, exercise, sl...

For decades, diseases have been classified by where they occur in the body. But that may not be the best way to treat them. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss biomarkers and why they are changing the future of medicine. They explore how two patients with the same diagnosis may have completely different underlying biology, why treatments s...

Drug discovery has changed dramatically over the past few decades. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss sit down with longtime colleague Dr. Hari Vankayalapati to discuss how the field has evolved and where it's headed next. Together, they reflect on lessons learned throughout their careers, including a philosophy that has shaped their approach...

Every year, promising therapies fail in clinical trials. But failure doesn't always mean the drug didn't work. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss explain how clinical trials work, why so many therapies never make it to patients, and the complexity behind bringing a new medicine to market. They discuss the different reasons a clinical tria...

The anti-aging industry promises longer life, but is that really the goal? In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss separate science from hype as they discuss what actually matters when it comes to aging. They explore why many age-related diseases are closely tied to the biology that helps us reproduce, why curing a single disease like cancer would add...

Gene editing has long felt like science fiction. Today, it is becoming a clinical reality. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss explore the rapid progress of gene editing and the opportunities and ethical questions that come with it. They discuss new evidence suggesting that a single treatment may be able to permanently edit genes in the liver to l...

Artificial intelligence is transforming medicine, but there is one major challenge that doesn't get enough attention. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss how AI models are trained, why scientific literature isn't always perfect, and what that means for the future of drug discovery. They explore how inaccurate or noisy data can infl...

Many of the medicines we rely on today came from unexpected places. In this episode of the Good Medicine Podcast, Dr. Jeremiah Bearss sits down with Nathan Chow to explore the origins of modern pharmacology and the surprising discoveries that shaped medicine as we know it. They discuss how the synthetic dye industry played a major role in the development of modern drug discovery, why curiosity has...

Modern medicine can do incredible things. But sometimes the best care is knowing when not to intervene. In this episode of the Good Medicine Podcast, Dr. Jeremiah Bearss sits down with Dr. Amogh Havanur to discuss hospital practices, patient care, and the importance of focusing on the person rather than simply chasing numbers. They explore why unnecessary overnight interruptions may not always ben...

For years, people have been told to avoid the sun whenever possible. But is completely avoiding sunlight actually healthy? In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss the role sunlight plays in overall health and why some exposure may be beneficial. They explore research showing higher all-cause mortality in individuals who avoided sunlight, the c...

Sleep impacts nearly every aspect of human health. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss why sleep may be one of the most important and overlooked pillars of long-term health. They explore how poor sleep affects mood, metabolism, cardiovascular risk, obesity, and overall lifespan, as well as the biological consequences of even a single night...

GLP-1 drugs have changed the conversation around weight loss, but are they the complete solution? In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss the benefits and downsides of GLP-1 medications, including how they impact exercise, muscle mass, and long-term weight management. They explore why many people feel poorly while taking these medications, why...

Drug development takes an average of 15 years, costs billions of dollars, and most therapies still fail before reaching patients. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss one of the biggest problems in modern drug development: animal models that may not accurately predict what happens in humans. They explore why only a small percentage of thera...

Cancer is being diagnosed in younger people more than ever before. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss the growing trend of cancer diagnoses in individuals under the age of 50 and why this shift is raising concern. They explore data showing increased risk in younger generations, including a significant rise in colon cancer diagnoses compar...

The global landscape of drug development is changing rapidly. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss the rise of China as a major force in biotech and pharmaceutical innovation. Over the past several years, China has moved from a relatively small player to one of the most active regions for drug development and major deal-making. By changing...

A recent study is raising important questions about the relationship between anemia and cancer. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss new findings from the Karolinska Institute in Sweden that suggest a significant increase in cancer diagnoses shortly after the onset of anemia. They explore what “incident anemia” means, why iron deficiency is...

Brain injury is often misunderstood as damage to neurons alone. The reality is far more complex. In this episode of the Good Medicine Podcast, Dr. David Bearss sits down with Dr. Donna Cross to discuss her journey into building a company focused on treating brain-related diseases and the science behind her work. Dr. Cross shares how a personal connection to Alzheimer’s through a donor to her lab r...

Pelvic floor disorders affect millions of women, yet many struggle to find effective treatment. In this episode of the Good Medicine Podcast, Dr. David Bearss sits down with Dr. Gabi Niederauer, founder of Freyya, to discuss her journey and the work her team is doing to improve women’s health. Freyya has developed a device designed to help women perform pelvic floor therapy exercises correctly by...

Peptides are becoming increasingly popular, but how should we actually think about them? In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss how peptides fit into the broader landscape of supplements, drugs, and regulation. They explore why peptides are often treated more like supplements than pharmaceuticals, what that means for safety and effectiveness,...