Behind the Slides

What if a new therapy could improve overall survival in colon cancer by 8%? How much would the system charge for that breakthrough? The NYTimes recently featured a follow-up to the NEJM study on exercise in colon cancer lead by Dr. Chris Booth - today on Behind the Slides we discuss Exercise-umab, we discuss common sense oncology and common sense medicine and we discuss building an academic medica...

In the words of our previous guest Adam Mastroianni, “incentives are for losers” but what happens when we get to peak under the hood at how deeply incentives influence analysis of clinical trial data? Great discussion with Dr. Mike Putman, practicing rheumatologist, medical educator and thought leader on clinical trials, therapeutic development and medical education. We discuss recent news from rh...

A great discussion with Dr. Louise Aronson on corporatism and medicine.

David Lederer, a former academic clinician scientist and key opinion leader, academic journal editor who left the academy for industry joins us to discuss his career shift. We discuss the reasons behind the move, the successes of failures seen in both realms and the way to chart a meaningful path through it all.

Dr. Joel Topf (@kidney_boy) joins us on Behind The Slides to discuss modern medical education, building community of medical trainees and professionals on social media, and how we know what we know in medicine.

In this episode of Behind the Slides, Scott Matson sits down with Adam Mastroianni to explore the incentives, institutions, and hidden cultures that shape modern science. Using Adam’s widely discussed essays on scientific publishing, peer review, and the replication crisis as a starting point, the conversation expands into a broader discussion about how scientific systems reward productivity, nove...

Episode 003 — Manni Mohyuddin, MD Why does so much clinical research never make it to publication—and what does that mean for the evidence we trust? In this episode of Behind the Slides , we sit down with Manni Mohyuddin to examine how incentives shape the research ecosystem. We discuss the gap between conference abstracts and eventual publication, what gets published (and what doesn’t), and how t...

In this episode of Behind the Slides , we sit down with Lisa Rosenbaum for a wide-ranging conversation about the meaning and practice of medicine today. We explore how much agency physicians really have within the healthcare system, whether the challenges in primary care reflect deeper issues across the field, and how clinicians navigate purpose, responsibility, and constraint in their work. We al...

What does it actually mean to practice evidence-based medicine? In this episode, we sit down with Adam Cifu to unpack the gap between clinical evidence and real-world decision making. We explore how data is interpreted at the bedside, why guidelines don’t always translate cleanly into practice, and what it takes to think clearly in the face of uncertainty. This is a conversation about judgment, tr...