What's Your Problem?

Sonia Kastner is the founder and CEO of Pano. Sonia’s problem is this: How do you use data and machine learning to mitigate the damage caused by climate change? Pano mounts cameras on remote mountaintop towers, then sends images from the cameras to an AI model trained to spot wildfire smoke. The goal is to alert fire crews early, before the fire spreads. See omnystudio.com/listener for privacy inf...

Amit Sharma is the founder and CEO of Narvar. Narvar works with companies such as Sephora, Lululemon and Home Depot to manage the post-purchase phase of online shopping — tracking, alerts and returns. Around 10 percent of online purchases are returned and every return cuts into retailers’ profits. Amit’s problem is this: consumers have learned to love free returns, but can retailers afford them? S...

Danielle Feinberg is a Visual Effects Supervisor at Pixar Animation Studios. Danielle’s problem is this: How do you optimize technology so that you can spend more time being creative? Danielle Feinberg has worked at Pixar for 26 years. Earlier in her career, she was the director of photography on movies like Coco and Wall-E. She talks about how new software shapes creative work. See omnystudio.com...

Yaron Singer is the founder and CEO of Robust Intelligence. Yaron’s problem is this: How do you reduce AI’s security and reliability risks? Yaron was a computer science professor at Harvard and worked at Google before starting Robust Intelligence. The company’s software tests AI models and datasets for problems with performance and security. See omnystudio.com/listener for privacy information.

Chris Monroe is the co-founder and chief scientist of IonQ. Chris’s problem is this: How do you build a quantum computer that will actually work? Quantum computing has the potential to transform fields from drug development to clean energy to cybersecurity, but so far no one has been able to build a quantum computer that can reliably outperform existing computers. Monroe is also a physics professo...

Seven stocks are powering the market: Alphabet, Amazon, Apple, Meta, Microsoft, Nvidia and Tesla. How will they do in the second half of this year? Ethan Wu hosts as Rob ‘Value This’ Armstrong takes on Elaine ‘The Lex Flex’ Moore. In three rounds they pick their winners for the second half of 2023, and tell us why they chose them. If you enjoyed this preview of the new podcast Unhedged, subscribe...

Charles Fisher is the co-founder and CEO of Unlearn AI. Charles’ problem is this: How do you build an AI model that can predict human health? Charles and his colleagues have built a predictive model of health that is already being used in clinical trials, and might one day be deployed to predict individuals’ health outcomes. See omnystudio.com/listener for privacy information.

Laura Modi is the founder and CEO of Bobbie, a company that makes baby formula and sells it directly to parents. Laura’s problem is this: how do you launch a startup in a highly regulated industry that has pretty much been a duopoly for decades? Part of Laura’s answer is marketing, which raises another question: how do you get people to consider formula despite so much messaging that breastfeeding...

Xiao Wang is the founder of a company called Boundless. Xiao’s problem is this: How do you make it cheaper and easier for people to navigate the U.S. immigration system? Xiao moved to the U.S. from China when he was three years-old. For many years, he took for granted that immigration was slow, complicated, and expensive to navigate. With Boundless, he’s built a platform to help people who try to...

Henrik Stiesdal got his start in wind power back in the 70s. The price of oil had gone way up, and he wanted to help his parents figure out a cheaper source of electricity for their farm. He went on to help create the modern wind industry. Five decades later, he’s still pushing the frontier. See omnystudio.com/listener for privacy information.

One of the most amazing things about ChatGPT and other, similar AI models: Nobody really understands what they can do. Not even the people who build them. On today’s show, we talk with Sam Bowman about some of the mysteries at the heart of so-called large language models. Sam is on the faculty at NYU, he runs a research group at the AI company Anthropic and he is the author of the illuminating pap...

Dan Friedmann is the CEO of Carbon Engineering. The company is at the frontier of a new industry, direct air capture. They just broke ground on a big plant in Texas that will pull carbon dioxide out of the air. Dan’s problem is this: how do you bring the price of direct air capture way down? And how do you convince companies and governments to pay for scrubbing carbon out of the air? See omnystudi...

Does flying have to be bad for the environment? Val Miftakhov, the founder and CEO of ZeroAvia, doesn’t think so. His company built a plane that’s powered by hydrogen fuel, which produces zero carbon emissions. It had a successful test flight earlier this year and Miftakhov hopes it will be ready for commercial use by 2025.  See omnystudio.com/listener for privacy information.

Andrew Mason is the founder and CEO of Descript. Descript's software has made editing audio and video much simpler.  The company recently received a large investment from OpenAI, the company behind ChatGPT. It's a sign that Descript is moving toward using generative AI to generate words and pictures. What will that mean for the people who currently do that work? See omnystudio.com/listener for pri...

Andrew Ponec is co-founder and CEO of the energy storage company Antora Energy.  Andrew's problem is this: How can you store renewable energy in a way that is cheap enough and reliable enough for industrial use? He thinks the solution may be storing that energy as heat, in big blocks of graphite. See omnystudio.com/listener for privacy information.

Tammy Hsu and Michelle Zhu are the cofounders of Huue.  Their problem is this: how do you get bacteria to produce indigo dye? And how do you do it cheaply and reliably enough to replace the toxic petrochemical process that's currently used to dye billions of pairs of jeans a year? They're working with denim brands to commercialize their bacteria-produced dye.  See omnystudio.com/listener for priva...

Today's show is about a problem people have been trying to solve for a hundred years: how can we mass produce houses, like we do cars? Listen for a house that looks like a UFO, a giant mobile home boom, and a visit to a 21st-century construction site where workers are putting up a factory-built house. This episode's a co-production with our friends at Planet Money, and a follow-up to last week's i...

Alexis Rivas is the co-founder and CEO of Cover. His problem is: How do you build houses in a factory, the way you build cars? And how do you do it so they're cheaper and better than a traditionally built house? Cover is following the Tesla model: starting with a high-end product but aiming for the mass market. "Nail it and scale it," he says. See omnystudio.com/listener for privacy information.

Nina Tandon is the co-founder and CEO of a tissue engineering company called EpiBone. Her problem is this: How do you grow custom bone from patients' stem cells, at a price that makes sense? See omnystudio.com/listener for privacy information.

Microchips are the most important driver of technological progress in the modern world, and governments are fighting over who gets to make them. Right now, most cutting-edge chips are made in Taiwan, a country that China claims as part of its territory. The U.S. government is fighting to keep semiconductor technology out of China, and spending tens of billions of dollars to get companies to build...

It's our first anniversary and—almost 50 episodes in—Jacob Goldstein checks in with three past guests.  Drone delivery guy Keenan Wyrobek thinks he has solved a big problem holding back commercial drone delivery in America. Fruit-ripening maven Katherine Sizov is figuring out bananas. And Glenn Kelman of Redfin has some deep insights from a tough year in the real estate business. *The problems in...

Alice Zhang is the co-founder and CEO of Verge Genomics. Alice's problem is this: How do you use artificial intelligence to drive down the price of developing new drugs? The company is using AI to find new disease mechanisms to target, and to speed up drug development. If using AI can help experimental drugs succeed even a little more often than they do now, it'll be a big win.  See omnystudio.com...

When Austin Russell was 17 years old, he founded Luminar Technologies to work on a remote sensing technology called Lidar.  Today, Austin is one of the world's youngest self-made billionaires, and Luminar may be on the verge of solving Austin's problem: How do you make Lidar cheap enough and good enough to use in millions of cars? See omnystudio.com/listener for privacy information.

Chace Barber is the co-founder of Edison Motors. Chace's problem is this: How do you build electric logging trucks in rural Canada, with money you raised from people who follow you on TikTok? Chace started his career driving logging trucks. He loved the idea of Tesla's electric semi, but when it never arrived, he decided to build his own. If you’d like to keep up with the most recent news from thi...

Here's a bonus episode of a new show from Pushkin, Other People's Pockets. Have you ever wondered how your friend bought that vacation home or why that colleague of yours makes everyone meticulously split the tab down to the last Diet Coke? Other People's Pockets is a show about other people’s money. Host Maya Lau asks people from all walks of life to get radically transparent about their personal...